Auflistung nach Titel
Anzeige der Publikationen 3846-3865 von 11433
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2010-08-23BachelorarbeitExpression and purification of the primate foamy virus transmembrane envelope protein Seit dem Nachweis breit neutralisierender Antikörper (bNAb), welche von HIV-infizierten Menschen gebildet werden können, konzentrieren sich viele Ansätze auf die Induktion solcher Antikörper zur Entwicklung eines HIV ...
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2003-01-01ZeitschriftenartikelExpression of ICOS In Vivo Defines CD4+ Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10 The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did not yield information on the nature and function of ICOS-expressing T cells in vivo. We ...
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2020-10-06ZeitschriftenartikelExpression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has ...
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2012-07-18ZeitschriftenartikelExpression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
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2009-06-01DiplomarbeitExpression rekombinanter, von HIV-1 gp41 abgeleiteter Proteine für die Analyse der Immunpathogenese Zur Etablierung eines Endotoxin-freien Bacillus megaterium Produktionssystems wurden zehn mittels PCR amplifizierte, von HIV-1 g41 abgeleitete Fragmente hergestellt und in transformations-kompetente B. megaterium Protoplasten ...
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2018-08-09BachelorarbeitExpression und Analyse retroviraler immunsuppressiver Doma nen auf humanen Zellen Eine Vielzahl von Retroviren sind in der Lage, das Immunsystem des Wirtes durch verschiedene Mechanismen zu beeinflussen. Die isu-Domäne als ein Teil der retroviralen TM-Proteine p15E (PERV, MuLV), sowie gp41 (HIV-1) ...
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2006-09-01DissertationExpression und biologische Funktion von humanen endogenen Retroviren (HERVs), insbesondere von HERV-K Daten des humanen Genomprojektes zeigen, dass ca. 8% des gesamten humanen Genoms aus retroviralen Sequenzen besteht. Der überwiegende Teil dieser Proviren ist aufgrund verschiedener Mutationen defekt. Im Gegensatz zu ...
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2005-09-01DiplomarbeitExpression von porzinen endogenen Retroviren in metastasierenden Melanomen und Melanomzelllinien von Troll Schweinen Porzine endogene Retroviren (PERVs) sind im Genom aller Schweine integriert. Ihre Expression in normalen porzinen Geweben sowie in Tumoren und ihre biologische Rolle ist bisher nicht ausführlich untersucht worden. Im ...
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2014-03-19ZeitschriftenartikelExpression-analysis of the human endogenous retrovirus HERV-K in human astrocytic tumors Background: The human endogenous retrovirus K (HERV-K) has been acquired by the genome of human ancestors million years ago. It is the most complete of the HERVs with transcriptionally active gag, pol and env genes. ...
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2015-10-14ZeitschriftenartikelExtended Microbiological Characterization of Göttingen Minipigs in the Context of Xenotransplantation: Detection and Vertical Transmission of Hepatitis E Virus Xenotransplantation has been proposed as a solution to the shortage of suitable human donors. Pigs are currently favoured as donor animals for xenotransplantation of cells, including islet cells, or organs. To reduce the ...
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2018-01-30ZeitschriftenartikelExtended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Acinetobacter baumannii among horses entering a veterinary teaching hospital: The contemporary "Trojan Horse" Pathogens frequently associated with multi-drug resistant (MDR) phenotypes, including extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) and Acinetobacter baumannii isolated from horses admitted ...
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2019-04-30ZeitschriftenartikelExtended-Spectrum Beta-Lactamase (ESBL)-Producing Escherichia coli Isolated from Flies in the Urban Center of Berlin, Germany Background: The monitoring of antimicrobial resistance (AMR) in microorganisms that circulate in the environment is an important topic of scientific research and contributes to the development of action plans to combat the ...
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2019-12-12ZeitschriftenartikelExtensively drug-resistant Klebsiella pneumoniae ST307 outbreak, north-eastern Germany, June to October 2019 From June to October 2019, 17 patients (six infected, 11 colonised) with an extensively drug-resistant (XDR) Klebsiella pneumoniae strain were notified from four Western Pomerania medical facilities. The XDR K. pneumoniae ...
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2018-09-13ZeitschriftenartikelExternal Quality Assessment (EQA) for Molecular Diagnostics of Zika Virus: Experiences from an International EQA Programme, 2016–2018 Quality Control for Molecular Diagnostics (QCMD), an international provider for External Quality Assessment (EQA) programmes, has introduced a programme for molecular diagnostics of Zika virus (ZIKV) in 2016, which has ...
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2018-05-17ZeitschriftenartikelExternal Quality Assessment for Zika Virus Molecular Diagnostic Testing, Brazil We conducted an external quality assessment of Zika virus molecular diagnostic tests in Brazil using a new Zika virus standard. Of 15 laboratories, 73% showed limited sensitivity and specificity. Viral load estimates varied ...
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2023-10-05ZeitschriftenartikelExternal quality assessment of orthohantavirus and lymphocytic choriomeningitis virus molecular detection and serology in Europe, 2021 Background Rodent-borne viruses such as orthohantaviruses and arenaviruses cause considerable disease burden with regional and temporal differences in incidence and clinical awareness. Therefore, it is important to ...
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2016-01-12ZeitschriftenartikelExternal quality assessment studies for laboratory performance of molecular and serological diagnosis of Chikungunya virus infection Background: Since the re-emergence of Chikungunya virus (CHIKV) in Reunion in 2005 and the recent outbreak in the Caribbean islands with an expansion to the Americas the CHIK diagnostic became very important. Objectives: ...
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2017-05-01ZeitschriftenartikelExternal quality assessment study for ebolavirus PCR-diagnostic promotes international preparedness during the 2014 – 2016 Ebola outbreak in West Africa During the recent Ebola outbreak in West Africa several international mobile laboratories were deployed to the mainly affected countries Guinea, Sierra Leone and Liberia to provide ebolavirus diagnostic capacity. Additionally, ...
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2016-12-01Berichte und sonstige TexteExternal Quality Assurance (EQA) in Diagnostic Electron Microscopy (DEM) of Infectious Diseases: Aims and Roots, Results and Perspectives During the 1970s–80s, besides virus culture diagnostic electron microscopy (DEM)1 became a prime technique in clinical virology and laboratory diagnosis of infectious diseases. Today DEM appears on the retreat for several ...
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2013-05-27ZeitschriftenartikelExternal quality assurance of the first wave of the German Health Interview and Examination Survey for Adults (DEGS1) The quality management concept for the first wave of the German Health Interview and Examination Survey for Adults (DEGS1) included in addition to conducting internal quality assurance (QS) also the supervision by an ...