Browsing by Title
Now showing items 1211-1230 of 11425
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2017-11-10ZeitschriftenartikelCapturing virus evolution by proteomic bioinformatics: Hunting for characteristic mutations in the hepatitis E virus genome
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2018-06-05ZeitschriftenartikelCarbapenem non-susceptibility of Klebsiella pneumoniae isolates in hospitals from 2011 to 2016, data from the German Antimicrobial Resistance Surveillance (ARS) Background: Carbapenem resistance in Klebsiella pneumoniae is of significant public health concern and recently spread across several countries. We investigated the extent of carbapenem non-susceptibility in K. pneumoniae ...
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2010-11-18ZeitschriftenartikelCarbapenem-non-susceptible Enterobacteriaceae in Europe: conclusions from a meeting of national experts The emergence and global spread of carbapenemase-producing Enterobacteriaceae is of great concern to health services worldwide. These bacteria are often resistant to all beta-lactam antibiotics and frequently co-resistant ...
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2017-02-16ZeitschriftenartikelCarbapenem-resistance and pathogenicity of bovine Acinetobacter indicus-like isolates The objective of this study was to characterize blaOXA-23 harbouring Acinetobacter indicuslike strains from cattle including genomic and phylogenetic analyses, antimicrobial susceptibility testing and evaluation of ...
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2015-11-12ZeitschriftenartikelCarbapenemase-producing Enterobacteriaceae in Europe: assessment by national experts from 38 countries, May 2015 In 2012, the European Centre for Disease Prevention and Control (ECDC) launched the ‘European survey of carbapenemase-producing Enterobacteriaceae (EuSCAPE)’ project to gain insights into the occurrence and epidemiology ...
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2013-05-27ZeitschriftenartikelCardiorespiratory fitness among adults in Germany Results of the German Health Interview and Examination Survey for Adults (DEGS1)A high level of fitness is an indicator for a good health state. Therefore, cardiorespiratory fitness was examined in the cross-sectional German Health Interview Survey for Adults (DEGS1). Data from 3,030 test-qualified ...
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2021-02-17ZeitschriftenartikelCare for the chronically ill in Germany – The challenges during the COVID-19 pandemic The COVID-19 pandemic is posing major challenges to the health care sector. This scoping review compiles evidence concerning changes to health care service availability and utilisation as well as possible impacts on health ...
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2016-03-17ZeitschriftenartikelCarriage of Extended-Spectrum Beta-Lactamase-Plasmids Does Not Reduce Fitness but Enhances Virulence in Some Strains of Pandemic E. coli Lineages Pathogenic ESBL-producing E. coli lineages occur frequently worldwide, not only in a human health context but in animals and the environment, also in settings with low antimicrobial pressures. This study investigated the ...
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2012-11-21ZeitschriftenartikelCarrier prevalence, secondary household transmission and long-term shedding in two districts during the Escherichia coli O104:H4 outbreak in Germany, 2011 Background: From May-July 2011, Germany experienced a large Shiga toxin-producing E. coli (STEC) O104:H4 outbreak. Our objective was to identify the prevalence of STEC O104:H4 carriers in households in highly affected ...
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2020-06-08ZeitschriftenartikelCartography of opportunistic pathogens and antibiotic resistance genes in a tertiary hospital environment Although disinfection is key to infection control, the colonization patterns and resistomes of hospital-environment microbes remain underexplored. We report the first extensive genomic characterization of microbiomes, ...
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2018-10-23ZeitschriftenartikelCase report: A fatal case of cryptococcosis in an immunocompetent patient due to Cryptococcus deuterogattii (AFLP6/VGII) Introduction. Cryptococcosis in immunocompetent adults is a rare disease in Europe, mostly induced by members of the Cryptococcus gattii species complex. The diagnosis can be challenging due to its rarity, unspecific ...
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2018-05-10ZeitschriftenartikelCase-control study on risk factors for acute hepatitis E in Germany, 2012 to 2014 Background Notified cases of hepatitis E have increased 40-fold in the past 10 years in Germany. Food safety is a major concern as hepatitis E virus (HEV) RNA has been detected in ready-to-eat retail-level food products. ...
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2016-09-28ZeitschriftenartikelCases of alcohol poisoning involving in-patient treatment Alcohol poisonings represent the direct consequences of excess alcohol consumption. In 2014, in Germany 115,967 persons aged 10 to 79 years were treated as in-patients with the diagnosis “acute alcohol intoxication”. In ...
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2011-01-27ZeitschriftenartikelCases of community-acquired meticillin-resistant Staphylococcus aureus in an asylum seekers centre in Germany, November 2010 In an asylum seeker centre in Schleswig-Holstein, a resident was diagnosed with furuncle caused by a Panton-Valentine leukocidine (PVL)-positive community- acquired meticillin-resistant Staphylococcus aureus (CA-MRSA). ...
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2016-03-14ZeitschriftenartikelCausal or not: applying the Bradford Hill aspects of evidence to the association between Zika virus and microcephaly
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2008-07-23ZeitschriftenartikelCCR5Delta32 genotypes in a German HIV-1 seroconverter cohort and report of HIV-1 infection in a CCR5Delta32 homozygous individual Background: Homozygosity (Δ32/Δ32) for the 32 bp deletion in the chemokine receptor 5 (CCR5) gene is associated with strong resistance against HIV infection. Heterozygosity is associated with protection of HIV-1 disease ...
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2016-12-07ZeitschriftenartikelCD4-cell counts and presence of AIDS in HIV-positive patients entering specialized care—a comparison of migrant groups in the German ClinSurv HIV Cohort Study, 1999–2013 Background: Although early presentation to HIV-care is essential to ensure timely initiation of antiretroviral therapy, recent studies have shown that especially migrants present to HIV-care at a later stage of ...
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2019-08-06ZeitschriftenartikelCell Shape and Antibiotic Resistance Are Maintained by the Activity of Multiple FtsW and RodA Enzymes in Listeria monocytogenes Rod-shaped bacteria have two modes of peptidoglycan synthesis: lateral synthesis and synthesis at the cell division site. These two processes are controlled by two macromolecular protein complexes, the elongasome and ...
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2013-03-21ZeitschriftenartikelChallenges in diagnosing extrapulmonary tuberculosis in the European Union, 2011 In the European Union (EU) 72,334 tuberculosis (TB) cases were notified in 2011, of which 16,116 (22%) had extrapulmonary tuberculosis (EPTB). The percentage of TB cases with EPTB ranged from 4% to 48% in the reporting ...
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2021-02-17ZeitschriftenartikelChallenges in interpreting SARS-CoV-2 serological results in African countries A diagnosis of COVID-19 is based on a positive PCR test for SARS-CoV-2. Over the past year, PCR testing capacity has varied globally due to the availability of tests, and testing strategies have targeted mainly symptomatic ...