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Auflistung nach Autor "Wang, Bo"
Anzeige der Publikationen 1-15 von 15
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2018-10-23ZeitschriftenartikelA new hepatitis E virus genotype 2 strain identified from an outbreak in Nigeria, 2017 Wang, Bo; Akanbi, Olusola Anuoluwapo; Harms, Dominik; Adesina, Olufisayo; Osundare, Folakemi Abiodun; Naidoo, Dhamari; Deveaux, Isabel; Ogundiran, Opeayo; Ugochukwu, Uzoma; Mba, Nwando; Ihekweazu, Chikwe; Bock, ThomasBackground: In 2017 the Nigerian Ministry of Health notified the World Health Organization (WHO) of an outbreak of hepatitis E located in the north-east region of the country with 146 cases with 2 deaths. The analysis ...
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2022-02-02ZeitschriftenartikelAdvanced sequencing approaches detected insertions of viral and human origin in the viral genome of chronic hepatitis E virus patients Papp, C.‑Patrick; Biedermann, Paula; Harms, Dominik; Wang, Bo; Kebelmann, Marianne; Choi, Mira; Helmuth, Johannes; Corman, Victor M.; Thürmer, Andrea; Altmann, Britta; Klink, Patrycja; Hofmann, Jörg; Bock, C.‑ThomasThe awareness of hepatitis E virus (HEV) increased significantly in the last decade due to its unexpectedly high prevalence in high-income countries. There, infections with HEV-genotype 3 (HEV-3) are predominant which can ...
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2017-11-10ZeitschriftenartikelCapturing virus evolution by proteomic bioinformatics: Hunting for characteristic mutations in the hepatitis E virus genome Harms, Dominik; Wang, Bo; Papp, C. Patrick; Bock, Thomas
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2019-03-04ZeitschriftenartikelCharacterization of a hepatitis C virus genotype 1 divergent isolate from an HIV-1 coinfected individual in Germany assigned to a new subtype 1o Wang, Bo; Krüger, Luise; Machnowska, Patrycja; Eshetu, Amare; Gunsenheimer-Bartmeyer, Barbara; Bremer, Viviane; Hauser, Andrea; Bannert, Norbert; Bock, C. ThomasBackground HCV exhibits a high genetic diversity and is classified into 7 genotypes which are further divided into 86 confirmed subtypes. However, there are multiple isolates with unassigned subtypes. We aimed to amplify ...
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2019-01-03ZeitschriftenartikelComplete Genome Sequence of a Hepatitis E Virus Genotype 1e Strain from an Outbreak in Nigeria, 2017 Akanbi, Olusola Anuoluwapo; Harms, Dominik; Wang, Bo; Opaleye, Oluyinka Oladele; Adesina, Olufisayo; Osundare, Folakemi Abiodun; Ogunniyi, Abiodun; Naidoo, Dhamari; Devaux, Isabelle; Wondimagegnehu, Alemu; Peter, Clement; Ifeanyi, Okudo; Ogundiran, Opeayo; Ugochukwu, Uzoma; Mba, Nwando; Omilabu, Sunday A.; Ihekweazu, Chikwe; Bock, C. ThomasHepatitis E virus genotype 1 (HEV-1) is associated with large epidemics. Notably, HEV subtype 1e (HEV-1e) has caused HEV outbreaks in sub-Saharan Africa. We report here the second full-length genome sequence of an HEV-1e ...
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2017-02-22ZeitschriftenartikelDetection and genome characterization of four novel bat hepadnaviruses and a hepevirus in China Wang, Bo; Yang, Xing-Lou; Li, Wen; Zhu, Yan; Ge, Xing-Yi; Zhang, Li-Biao; Zhang, Yun-Zhi; Bock, Claus-Thomas; Shi, Zheng-LiBackground: In recent years, novel hepadnaviruses, hepeviruses, hepatoviruses, and hepaciviruses have been discovered in various species of bat around the world, indicating that bats may act as natural reservoirs for ...
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2021-06-29ZeitschriftenartikelDetection of Q129H Immune Escape Mutation in Apparently Healthy Hepatitis B Virus Carriers in Southwestern Nigeria Adesina, Olufisayo Adeyemi; Akanbi, Olusola Anuoluwapo; Opaleye, Oluyinka Oladele; Japhet, Margaret Oluwatoyin; Wang, Bo; Oluyege, Adekemi Olubukunola; Klink, Patrycja; Bock, C.-ThomasAs the global effort to eradicate hepatitis B continues, immune escape mutations (IEMs) and drug resistance mutations (DRMs) affecting its diagnosis, treatment, and prevention are compromising this goal. However, knowledge ...
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2021-04-29ZeitschriftenartikelHepatitis E virus infection in high-risk populations in Osun State, Nigeria Osundare, Folakemi Abiodun; Klink, Patrycja; Akanbi, Olusola Aanuoluwapo; Wang, Bo; Harms, Dominik; Ojurongbe, Olusola; Ajayi, Moses Adedapo; Babaranti, Emmanuel Oluwagbenga; Bock, C.-Thomas; Opaleye, Oladele OluyinkaHepatitis E virus (HEV) infection is an emerging infection that is of major public health concern, especially in some vulnerable groups like immunosuppressed individuals, pregnant women and HBV-coinfected individuals. HEV ...
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2016-08-06ZeitschriftenartikelHepatitis E Virus Mutations: Functional and Clinical Relevance Tong, Hoang van; Hoan, Nghiem Xuan; Wang, Bo; Wedemeyer, Heiner; Bock, Thomas; Velavan, Thirumalaisamy P.Hepatitis E virus (HEV) infection is a major cause of acute hepatitis and affects more than 20 million individuals, with three million symptomatic cases and 56,000 recognized HEV-related deaths worldwide. HEV is endemic ...
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2019-06-26ZeitschriftenartikelHigh Hepatitis E virus (HEV) Positivity Among Domestic Pigs and Risk of HEV Infection of Individuals Occupationally Exposed to Pigs and Pork Meat in Hanoi, Vietnam Xuan Hoan, Nghiem; Xuan Huy, Pham; Tien Sy, Bui; Meyer, Christian G.; Van Son, Trinh; Thanh Binh, Mai; Phuong Giang, Dao; Tu Anh, Dam; Bock, Claus-Thomas; Wang, Bo; Van Tong, Hoang; Kremsner, Peter G.; Hu Song, Lee; Linh Toan, Nguyen; Velavan, Thirumalaisamy P.Background Hepatitis E virus (HEV) infection can occur through consumption of undercooked pork meat or exposure to animal feces. Because there are scarce data only in developing countries, we assessed whether pigs might ...
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2017-05-18ZeitschriftenartikelIdentification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland Wang, Bo; Harms, Dominik; Hofmann, Jörg; Ciardo, Diana; Kneubühl, Agnes; Bock, ThomasHepatitis E virus genotype 3 (HEV-3) is the causal pathogen of chronic hepatitis E. We report here the full-length genome sequence of an HEV-3 strain, isolated from a kidney transplant recipient in Switzerland (SW/16-0282). ...
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2016-01-14ZeitschriftenartikelMolecular epidemiology of hepatitis D virus circulating in Southwestern Nigeria Opaleye, Oluyinka Oladele; Japhet, Oluwatoyin Margaret; Adewumi, Olubusuyi Moses; Omoruyi, Ewean Chukwuma; Akanbi, Olusola Anuoluwapo; Oluremi, Adeolu Sunday; Wang, Bo; Tong, Hoang van; Velavan, Thirumalaisamy P.; Bock, ThomasBackground: Hepatitis B virus (HBV) and hepatitis D virus (HDV) infections are major public health problems in sub-Saharan Africa. Whereas it is known that HBV infection is endemic in Nigeria, there is only little data ...
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2020-02-25ZeitschriftenartikelOrthohepevirus C: An Expanding Species of Emerging Hepatitis E Virus Variants Wang, Bo; Harms, Dominik; Yang, Xing-Lou; Bock, Claus-ThomasHepatitis E virus (HEV) is an emerging zoonotic pathogen that has received an increasing amount of attention from virologists, clinicians, veterinarians, and epidemiologists over the past decade. The host range and animal ...
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2021-01-15ZeitschriftenartikelPrevalence and characteristics of hepatitis B and D virus infections among HIV-positive individuals in Southwestern Nigeria Opaleye, Oluyinka Oladele; Akanbi, Olusola Anuoluwapo; Osundare, Folakemi Abiodun; Wang, Bo; Adesina, Olufisayo; Sunday, Sola Thomas; Akindele, Abiodun Akeem; Klink, Patrycja; Bock, C. ThomasBackground Coinfections of HIV-positive individuals with Hepatitis B and D virus (HBV and HDV) are common and can be associated with rapid liver damage. Several antiretroviral drugs for HIV exhibit anti-HBV effect; ...
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2020-03-24ZeitschriftenartikelSpecific circulating microRNAs during hepatitis E infection can serve as indicator for chronic hepatitis E Harms, Dominik; Choi, Mira; Allers, Kristina; Wang, Bo; Pietsch, Heiko; Papp, C.-Patrick; Hanisch, Lina; Kurreck, Jens; Hofmann, Jörg; Bock, C.-ThomasHepatitis E virus (HEV) genotypes 3 and 4 (HEV-3, HEV-4) infections are an emerging public health issue in industrialized countries. HEV-3 and −4 are usually self-limiting but can progress to chronic hepatitis E in ...