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Auflistung nach Autor "Walther, Birgit"
Anzeige der Publikationen 1-18 von 18
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2016-01-22ZeitschriftenartikelA Look into the Melting Pot: The mecC-Harboring Region Is a Recombination Hot Spot in Staphylococcus stepanovicii Semmler, Torsten; Harrison, Ewan M.; Lübke-Becker, Antina; Ulrich, Rainer G.; Wieler, Lothar H.; Guenther, Sebastian; Stamm, Ivonne; Hanssen, Anne-Merethe; Holmes, Mark A.; Vincze, Szilvia; Walther, BirgitIntroduction: Horizontal gene transfer (HGT) is an important driver for resistance- and virulence factor accumulation in pathogenic bacteria such as Staphylococcus aureus. Methods: Here, we have investigated the ...
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2021-05-16ZeitschriftenartikelA Pilot Randomised Clinical Trial Comparing a Short-Term Perioperative Prophylaxis Regimen to a Long-Term Standard Protocol in Equine Colic Surgery Stöckle, Sabita Diana; Kannapin, Dania A.; Kauter, Anne M. L.; Lübke-Becker, Antina; Walther, Birgit; Merle, Roswitha; Gehlen, HeidrunFor surgical interventions classified as clean or clean-contaminated, including laparotomy, guidelines in human and veterinary medicine recommend a short-term perioperative antibiotic prophylaxis (PAP). In equine colic ...
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2014-01-20ZeitschriftenartikelAlarming Proportions of Methicillin-Resistant Staphylococcus aureus (MRSA) in Wound Samples from Companion Animals, Germany 2010–2012 Vincze, Szilvia; Stamm, Ivonne; Kopp, Peter A.; Hermes, Julia; Adlhoch, Cornelia; Semmler, Torsten; Wieler, Lothar H.; Lübke-Becker, Antina; Walther, BirgitStaphylococcus (S.) aureus is an important cause of wound infections in companion animals, and infections with methicillin-resistant S. aureus (MRSA) are of particular concern due to limited treatment options and their ...
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2018-10-22ZeitschriftenartikelBringing together what belongs together: Optimizing murine infection models by using mouse-adapted Staphylococcus aureus strains Trübe, Patricia; Hertlein, Tobias; Mrochen, Daniel M.; Schulz, Daniel; Jorde, Ilka; Krause, Bettina; Zeun, Julia; Fischer, Stefan; Wolf, Silver A.; Walther, Birgit; Semmler, Torsten; Bröker, Barbara M.; Ulrich, Rainer G.; Ohlsen, Knut; Holtfreter, SilvaStaphylococcus (S.) aureus is a leading cause of bacterial infection world-wide, and currently no vaccine is available for humans. Vaccine development relies heavily on clinically relevant infection models. However, the ...
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2018-09-10ZeitschriftenartikelComparative Secretome Analyses of Human and Zoonotic Staphylococcus aureus Isolates CC8, CC22, and CC398 Busche, Tobias; Hillion, Mélanie; Van Loi, Vu; Berg, David; Walther, Birgit; Semmler, Torsten; Strommenger, Birgit; Witte, Wolfgang; Cuny, Christiane; Mellmann, Alexander; Holmes, Mark A.; Kalinowski, Jörn; Adrian, Lorenz; Bernhardt, Jörg; Antelmann, HaikeThe spread of methicillin-resistant Staphylococcus aureus (MRSA) in the community, hospitals and in livestock is mediated by highly diverse virulence factors that include secreted toxins, superantigens, enzymes and ...
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2019-11-28ZeitschriftenartikelEffects of a Four-Week High-Dosage Zinc Oxide Supplemented Diet on Commensal Escherichia coli of Weaned Pigs Johanns, Vanessa C.; Ghazisaeedi, Fereshteh; Epping, Lennard; Semmler, Torsten; Lübke-Becker, Antina; Pfeifer, Yvonne; Bethe, Astrid; Eichhorn, Inga; Merle, Roswitha; Walther, Birgit; Wieler, Lothar H.Strategies to reduce economic losses associated with post-weaning diarrhea in pig farming include high-level dietary zinc oxide supplementation. However, excessive usage of zinc oxide in the pig production sector was found ...
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2018-10-24ZeitschriftenartikelEquine Methicillin-Resistant Sequence Type 398 Staphylococcus aureus (MRSA) Harbor Mobile Genetic Elements Promoting Host Adaptation Walther, Birgit; Klein, Katja-Sophia; Barton, Ann-Kristin; Semmler, Torsten; Huber, Charlotte; Merle, Roswitha; Tedin, Karsten; Mitrach, Franziska; Lübke-Becker, Antina; Gehlen, HeidrunContinuing introduction of multi-drug resistant, zoonotic pathogens such as methicillin-resistant Staphylococcus aureus (MRSA) in horse clinics challenges the biosafety of employees and animal patients. This study was aimed ...
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2018-01-30ZeitschriftenartikelExtended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Acinetobacter baumannii among horses entering a veterinary teaching hospital: The contemporary "Trojan Horse" Walther, Birgit; Klein, Katja-Sophia; Barton, Ann-Kristin; Semmler, Torsten; Huber, Charlotte; Wolf, Silver Anthony; Tedin, Karsten; Merle, Roswitha; Mitrach, Franziska; Guenther, Sebastian; Lübke-Becker, Antina; Gehlen, HeidrunPathogens frequently associated with multi-drug resistant (MDR) phenotypes, including extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae (ESBL-E) and Acinetobacter baumannii isolated from horses admitted ...
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2021-04-16ZeitschriftenartikelFrequency, Local Dynamics, and Genomic Characteristics of ESBL-Producing Escherichia coli Isolated From Specimens of Hospitalized Horses Kauter, Anne; Epping, Lennard; Ghazisaeed, Fereshteh; Lübke-Becker, Antina; Wolf, Silver A.; Kannapin, Dania; Stoeckle, Sabita D.; Semmler, Torsten; Günther, Sebastian; Gehlen, Heidrun; Walther, BirgitPrevious research identified veterinary clinics as hotspots with respect to accumulation and spread of multidrug resistant extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (EC). Therefore, promoting the ...
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2021-05-14ZeitschriftenartikelGenome‑wide insights into population structure and host specifcity of Campylobacter jejuni Epping, Lennard; Walther, Birgit; Piro, Rosario M.; Knüver, Marie‑Theres; Huber, Charlotte; Thürmer, Andrea; Flieger, Antje; Fruth, Angelika; Janecko, Nicol; Wieler, Lothar H.; Stingl, Kerstin; Semmler, TorstenThe zoonotic pathogen Campylobacter jejuni is among the leading causes of foodborne diseases worldwide. While C. jejuni colonises many wild animals and livestock, persistence mechanisms enabling the bacterium to adapt to ...
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2019-09-13ZeitschriftenartikelMolecular Characterization of Equine Staphylococcus aureus Isolates Exhibiting Reduced Oxacillin Susceptibility Scholtzek, Anissa D.; Hanke, Dennis; Walther, Birgit; Eichhorn, Inga; Stöckle, Sabita D.; Klein, Katja-Sophia; Gehlen, Heidrun; Lübke-Becker, Antina; Schwarz, Stefan; Feßler, Andrea T.The detection of borderline oxacillin-resistant Staphylococcus aureus (BORSA) represents a challenge to both, veterinary and human laboratories. Between 2015 and 2017, 19 equine S. aureus with elevated minimal inhibitory ...
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2013-08-01ZeitschriftenartikelMRSA bei Haustieren: Bedeutung für den Menschen Köck, Robin; Cuny, Christiane; Walther, BirgitMethicillin-resistente Staphylococcus aureus (MRSA) sind wichtige Infektionserreger bei Haustieren und bei Menschen. Untersuchungen zur zoonotischen Bedeutung des Erregers haben gezeigt, dass MRSA zwischen Mensch und ...
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2014-02-04ZeitschriftenartikelPhylogenetic Analysis of Staphylococcus aureus CC398 Reveals a Sub-Lineage Epidemiologically Associated with Infections in Horses Abdelbary, Mohamed M. H.; Wittenberg, Anne; Cuny, Christiane; Layer, Franziska; Kurt, Kevin; Wieler, Lothar H.; Walther, Birgit; Skov, Robert; Larsen, Jesper; Hasman, Henrik; Fitzgerald, J. Ross; Smith, Tara C.; Wagenaar, J. A.; Pantosti, Annalisa; Hallin, Marie; Struelens, Marc J.; Edwards, Giles; Böse, R.; Nübel, Ulrich; Witte, WolfgangIn the early 2000s, a particular MRSA clonal complex (CC398) was found mainly in pigs and pig farmers in Europe. Since then, CC398 has been detected among a wide variety of animal species worldwide. We investigated the ...
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2012-04-18ZeitschriftenartikelSharing more than friendship--nasal colonization with coagulase-positive staphylococci (CPS) and co-habitation aspects of dogs and their owners. Walther, Birgit; Hermes, Julia; Cuny, Christiane; Wieler, Lothar H.; Vincze, Szilvia; Elnaga, Yassmin Abou; Stamm, Ivonne; Kopp, Peter A.; Kohn, Barbara; Witte, Wolfgang; Jansen, Andreas; Conraths, Franz J.; Semmler, Torsten; Eckmanns, Tim; Lübke-Becker, AntinaBackground: Since the relationship between dogs and their owners has changed, and dogs moved from being working dogs to family members in post-industrial countries, we hypothesized that zoonotic transmission of opportunistic ...
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2020-09-08ZeitschriftenartikelSilence as a way of niche adaptation: mecC-MRSA with variations in the accessory gene regulator (agr) functionality express kaleidoscopic phenotypes Huber, Charlotte; Stamm, Ivonne; Ziebuhr, Wilma; Marincola, Gabriella; Bischoff, Markus; Strommenger, Birgit; Jaschkowitz, Greta; Marciniak, Tessa; Cuny, Christiane; Witte, Wolfgang; Doellinger, Joerg; Schaudinn, Christoph; Thürmer, Andrea; Epping, Lennard; Semmler, Torsten; Lübke-Becker, Antina; Wieler, Lothar H.; Walther, BirgitFunctionality of the accessory gene regulator (agr) quorum sensing system is an important factor promoting either acute or chronic infections by the notorious opportunistic human and veterinary pathogen Staphylococcus ...
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2019-11-13ZeitschriftenartikelThe gut microbiome of horses: current research on equine enteral microbiota and future perspectives Kauter, Anne; Epping, Lennard; Semmler, Torsten; Antao, Esther-Maria; Kannapin, Dania; Stoeckle, Sabita D.; Gehlen, Heidrun; Lübke-Becker, Antina; Günther, Sebastian; Wieler, Lothar H.; Walther, BirgitUnderstanding the complex interactions of microbial communities including bacteria, archaea, parasites, viruses and fungi of the gastrointestinal tract (GIT) associated with states of either health or disease is still an ...
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2023-05-15ZeitschriftenartikelTherapierelevante Antibiotikaresistenzen im One-Health-Kontext Werner, Guido; Abu Sin, Muna; Bahrs, Christina; Brogden, Sandra; Feßler, Andrea T.; Hagel, Stefan; Kaspar, Heike; Köck, Robin; Kreienbrock, Lothar; Krüger-Haker, Henrike; Maechler, Frederike; Noll, Ines; Pletz, Matthias W.; Tenhagen, Bernd-Alois; Schwarz, Stefan; Walther, Birgit; Mielke, Martin„One Health“ bezeichnet ein Konzept, das die Gesundheit von Menschen, Tieren und der Umwelt miteinander verbindet. In Deutschland gibt es umfangreiche Daten zur Antibiotikaresistenz (AMR) und multiresistenten Erregern (MRE) ...
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2017-09-22ZeitschriftenartikelWild rodents and shrews are natural hosts of Staphylococcus aureus Mrochen, Daniel M.; Schulz, Daniel; Fischer, Stefan; Jeske, Kathrin; El Gohary, Heba; Reil, Daniela; Imholt, Christian; Trübe, Patricia; Suchomel, Josef; Tricaud, Emilie; Jacob, Jens; Heroldová, Marta; Bröker, Barbara M.; Strommenger, Birgit; Walther, Birgit; Ulrich, Rainer G.; Holtfreter, SilvaLaboratory mice are the most commonly used animal model for Staphylococcus aureus infection studies. We have previously shown that laboratory mice from global vendors are frequently colonized with S. aureus. Laboratory ...