2023-04-04Zeitschriftenartikel
Heterozygosity for cervid S138N polymorphism results in subclinical CWD in gene-targeted mice and progressive inhibition of prion conversion
Arifin, Maria I.; Kaczmarczyk, Lech; Zeng, Doris; Hannaoui, Samia; Lee, Chi; Chang, Sheng Chun; Mitchell, Gordon; McKenzie, Debbie; Beekes, Michael; Jackson, Walker; Gilch, Sabine
Prions are proteinaceous infectious particles that replicate by structural conversion of the host-encoded cellular prion protein (PrPC), causing fatal neurodegenerative diseases in mammals. Species-specific amino acid ...
