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Now showing items 141-160 of 13713
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2019-03-19ZeitschriftenartikelA Novel Orthohepadnavirus Identified in a Dead Maxwell’s Duiker (Philantomba maxwellii) in Taï National Park, Côte d’Ivoire New technologies enable viral discovery in a diversity of hosts, providing insights into viral evolution. We used one such approach, the virome capture sequencing for vertebrate viruses (VirCapSeq-VERT) platform, on 21 ...
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2019-11-04ZeitschriftenartikelA patatin-like phospholipase functions during gametocyte induction in the malaria parasite Plasmodium falciparum Patatin-like phospholipases (PNPLAs) are highly conserved enzymes of prokaryotic and eukaryotic organisms with major roles in lipid homeostasis. The genome of the malaria parasite Plasmodium falciparum encodes four putative ...
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2023-09-09ZeitschriftenartikelA Person-Centered Perspective on Physical Activity-Related Barriers Perceived by Male Fluctuators 50 Plus: A Cross-Sectional Study Men aged 50 or older (50 plus) represent a hard-to-reach target group for health-enhancing physical activity (PA) interventions. However, a considerable percentage of men 50 plus do not entirely fail to achieve the PA ...
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2021-05-16ZeitschriftenartikelA Pilot Randomised Clinical Trial Comparing a Short-Term Perioperative Prophylaxis Regimen to a Long-Term Standard Protocol in Equine Colic Surgery For surgical interventions classified as clean or clean-contaminated, including laparotomy, guidelines in human and veterinary medicine recommend a short-term perioperative antibiotic prophylaxis (PAP). In equine colic ...
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2020-04-06ZeitschriftenartikelA Placenta Derived C-Terminal Fragment of β-Hemoglobin With Combined Antibacterial and Antiviral Activity The placenta acts as physical and immunological barrier against the transmission of viruses and bacteria from mother to fetus. However, the specific mechanisms by which the placenta protects the developing fetus from viral ...
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2022-08-31ZeitschriftenartikelA planetary health perspective on the climate crisis
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2020-09-21ZeitschriftenartikelA Plasmodium cysteine protease required for efficient transition from the liver infection stage The transitions between developmental stages are critical points in the Plasmodium life cycle. The development of Plasmodium in the livers of their mammalian hosts bridges malaria transmission and the onset of clinical ...
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2021-08-27ZeitschriftenartikelA pre-registered short-term forecasting study of COVID-19 in Germany and Poland during the second wave Disease modelling has had considerable policy impact during the ongoing COVID-19 pandemic, and it is increasingly acknowledged that combining multiple models can improve the reliability of outputs. Here we report insights ...
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2019-11-21ZeitschriftenartikelA probable case of tick-borne encephalitis (TBE) acquired in England, July 2019 The United Kingdom (UK) has thus far been considered to be free from tick-borne encephalitis (TBE), yet in July 2019, a German infant developed serologically diagnosed TBE following a tick bite in southern England. This ...
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2011-03-05ZeitschriftenartikelA quantitative approach to analyse linkages between antimicrobial resistance properties in Salmonella Typhimurium isolates This study used statistical methods to investigate linkages in phenotypic resistance profiles in a population sample of 321 Salmonella Typhimurium isolates from sporadic salmonellosis cases in Lower Saxony, Germany, collected ...
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2021-04-14ZeitschriftenartikelA Real-Time Thermal Sensor System for Quantifying the Inhibitory Effect of Antimicrobial Peptides on Bacterial Adhesion and Biofilm Formation The increasing rate of antimicrobial resistance (AMR) in pathogenic bacteria is a global threat to human and veterinary medicine. Beyond antibiotics, antimicrobial peptides (AMPs) might be an alternative to inhibit the ...
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2025-06StudienarbeitA Real-World Evidence Study Using German Cancer Registry Data to Explore the Epidemiology, Treatment Patterns, and Outcomes in Patients with Locally Advanced/Metastatic Urothelial Carcinoma Das Urothelkarzinom (UC) umfasst Blasen-, obere Harntrakt- und Harnröhrenkarzinome und kann sich in folgenden Stadien präsentieren: nicht-muskelinvasiv, muskelinvasiv, lokal fortgeschritten/metastasiert (la/mUC). Das la/mUC ...
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2020-05-27ZeitschriftenartikelA Recent Human Immunodeficiency Virus Outbreak Among People Who Inject Drugs in Munich, Germany, Is Associated With Consumption of Synthetic Cathinones Background. Needle and syringe sharing among people who inject drugs (PWID) can result in a rapid regional spread of a human immunodeficiency virus (HIV) variant. Such outbreaks have been identified recently in several ...
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2026-09StudienarbeitA Resectable GALLbladder and bile duct cancer studY based on real-world data from federal state cancer registries in Germany (ReGALLY) Für zwei thematisch eng verbundene Fragestellungen sollen bevölkerungsbezogene Krebsregisterdaten (epidemiologischer Datensatz, klinischer Datensatz) verwendet werden. Die Analysen sollen für Gesamtgruppe und die Subgruppen ...
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2019-08-16ZeitschriftenartikelA Robust and Universal Metaproteomics Workflow for Research Studies and Routine Diagnostics Within 24 h Using Phenol Extraction, FASP Digest, and the MetaProteomeAnalyzer The investigation of microbial proteins by mass spectrometry (metaproteomics) is a key technology for simultaneously assessing the taxonomic composition and the functionality of microbial communities in medical, environmental, ...
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2017-11-14ZeitschriftenartikelA Role of Sp1 Binding Motifs in Basal and Large T-Antigen-Induced Promoter Activities of Human Polyomavirus HPyV9 and Its Variant UF-1 Human polyomavirus 9 (HPyV9) was originally detected in the serum of a renal transplant patient. Seroepidemiological studies showed that ~20–50% of the human population have antibodies against this virus. HPyV9 has not yet ...
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2021-02-03ZeitschriftenartikelA Sarcina bacterium linked to lethal disease in sanctuary chimpanzees in Sierra Leone Human and animal infections with bacteria of the genus Sarcina (family Clostridiaceae) are associated with gastric dilation and emphysematous gastritis. However, the potential roles of sarcinae as commensals or pathogens ...
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2013-03-21ZeitschriftenartikelA screening tool to prioritize public health risk associated with accidental or deliberate release of chemicals into the atmosphere The Chemical Events Working Group of the Global Health Security Initiative has developed a flexible screening tool for chemicals that present a risk when accidentally or deliberately released into the atmosphere. The tool ...
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2024-10-14ZeitschriftenartikelA seroprevalence study indicates a high proportion of clinically undiagnosed MPXV infections in men who have sex with men in Berlin, Germany Introduction: During the mpox outbreak in 2022, the highest number of cases in Germany were registered in Berlin, almost all of them in men who have sex with men (MSM). However, the frequency of clinically undiagnosed ...
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2018-05-29ZeitschriftenartikelA set of prevention indicators for Bavaria – core data on prevention for Bavaria and its regions