Browsing by Author "Jacob, Daniela"

Now showing items 21-30 of 30

2020-10-23Zeitschriftenartikel

Outbreak of Tularemia in a Group of Hunters in Germany in 2018 - Kinetics of Antibody and Cytokine Responses

Jacob, Daniela; Barduhn, Anne; Tappe, Dennis; Rauch, Jessica; Heuner, Klaus; Hierhammer, Daniela; vom Berge, Katharina; Riehm, Julia M.; Hanczaruk, Matthias; Böhm, Stefanie; Böhmer, Merle M.; Konrad, Regina; Bouschery, Berit; Dauer, Marc; Schichtl, Elisabeth; Hossain, Hamid; Grunow, Roland

In November 2018, an outbreak of tularemia occurred among hare hunters in Bavaria, Germany. At least one infected hare was confirmed as the source of infection. A number of hunting dogs showed elevated antibody titers to ...
2010-04-30Zeitschriftenartikel

Pentaplexed quantitative real-time PCR assay for the simultaneous detection and quantification of botulinum neurotoxin-producing clostridia in food and clinical samples

Kirchner, Sebastian; Krämer, Melanie; Schulze, Martin; Pauly, Diana; Jacob, Daniela; Gessler, Frank; Nitsche, Andreas; Dorner, Brigitte; Dorner, Martin

Botulinum neurotoxins are produced by the anaerobic bacterium Clostridium botulinum and are divided into seven distinct serotypes (A to G) known to cause botulism in animals and humans. In this study, a multiplexed ...
2018-03-22Zeitschriftenartikel

Population Genomics of Francisella tularensis subsp. holarctica and its Implication on the Eco-Epidemiology of Tularemia in Switzerland

Wittwer, Matthias; Altpeter, Ekkehard; Pilo, Paola; Gygli, Sebastian M.; Beuret, Christian; Foucault, Frederic; Ackermann-Gäumann, Rahel; Karrer, Urs; Jacob, Daniela; Grunow, Roland; Schürch, Nadia

Whole genome sequencing (WGS) methods provide new possibilities in the field of molecular epidemiology. This is particularly true for monomorphic organisms where the discriminatory power of traditional methods (e.g., ...
2012-06-29Zeitschriftenartikel

Rapid and high-throughput detection of highly pathogenic bacteria by Ibis PLEX-ID technology

Jacob, Daniela; Sauer, Ursula; Housley, Roberta; Washington, Cicely; Sannes-Lowery, Kristin; Ecker, David J.; Sampath, Rangarajan; Grunow, Roland

In this manuscript, we describe the identification of highly pathogenic bacteria using an assay coupling biothreat group-specific PCR with electrospray ionization mass spectrometry (PCR/ESI-MS) run on an Ibis PLEX-ID ...
2020-05-27Zeitschriftenartikel

The Burkholderia thailandensis Phages ΦE058 and ΦE067 Represent Distinct Prototypes of a New Subgroup of Temperate Burkholderia Myoviruses

Hammerl, Jens A.; Volkmar, Sven; Jacob, Daniela; Klein, Iris; Jäckel, Claudia; Hertwig, Stefan

Burkholderia mallei and B. pseudomallei are highly pathogenic species which are closely related, but diverse regarding their prophage content. While temperate phages have not yet been isolated from B. mallei, several phages ...
2018-02-16Zeitschriftenartikel

Tularemia in Germany—A Re-emerging Zoonosis

Faber, Mirko; Heuner, Klaus; Jacob, Daniela; Grunow, Roland

Tularemia, also known as “rabbit fever,” is a zoonosis caused by the facultative intracellular, gram-negative bacterium Francisella tularensis. Infection occurs through contact with infected animals (often hares), arthropod ...
2022-08-17Zeitschriftenartikel

Ulceroglandular form of tularemia after squirrel bite: a case report

Borgschulte, Hannah Sopia; Jacob, Daniela; Zeeh, Jörg; Scholz, Holger C.; Heuner, Klaus

Background The diagnosis of tularemia is not often considered in Germany as the disease is still rare in this country. Nonetheless, Francisella tularensis, the causative agent of tularemia, can infect numerous animal ...
2025-07-03Zeitschriftenartikel

Vibrionen in Gewässern Deutschlands

Dupke, Susann; Walther, Birgit; Hammerl, Jens-Andre; Jacob, Daniela

Bakterien der Gattung Vibrio (Vibrionen) sind weltweit natürlicher Bestandteil mikrobieller Meer- und Süßwassergemeinschaften. Sie kommen freischwimmend in der Wassersäule vor oder sind an biotische oder abiotische Oberflächen ...
2005-06-20Zeitschriftenartikel

Viral promoters can initiate expression of toxin genes introduced into Escherichia coli

Lewin, Astrid; Mayer, Martin; Chusainow, Janet; Jacob, Daniela; Appel, Bernd

Background: The expression of recombinant proteins in eukaryotic cells requires the fusion of the coding region to a promoter functional in the eukaryotic cell line. Viral promoters are very often used for this purpose. ...
2011-12-01Zeitschriftenartikel

Wirksame Desinfektionsmittel gegen bakterielle Erreger der Risikogruppe 3

Appel, Bernd; Becker, Silke; Grunow, Roland; Jacob, Daniela; Klee, Silke; Nattermann, Herbert

Mit Suspensions- und Keimträgerversuchen wurde die sporizide Wirkung von unterschiedlichen Konzentrationen von Formaldehyd- sowie wässriger und alkoholischer Peressigsäure- (PES-) Lösungen auf Milzbrandsporen untersucht. ...