Browsing by Title
Now showing items 2251-2270 of 12440
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2012-10-03ZeitschriftenartikelDirect Detection and Genotyping of KPC Carbapenemases from Urine using a new DNA Microarray Test Klebsiella pneumoniae carbapenemases (KPC) are considered a serious threat to antibiotic therapy as they confer resistance to carbapenems, which are used to treat Extended-spectrum beta-lactamase (ESBL) producing bacteria. ...
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2013-11-05ZeitschriftenartikelDirect RNA-Based Detection and Differentiation of CTX-M-Type Extended-Spectrum β-Lactamases (ESBL) The current global spread of multi-resistant Gram-negatives, particularly extended spectrum β-lactamases expressing bacteria, increases the likelihood of inappropriate empiric treatment of critically ill patients with ...
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2010-10-31ZeitschriftenartikelDirect Visualization of Peptide/MHC Complexes at the Surface and in the Intracellular Compartments of Cells Infected In Vivo by Leishmania major Protozoa and bacteria infect various types of phagocytic cells including macrophages, monocytes, dendritic cells and eosinophils. However, it is not clear which of these cells process and present microbial antigens in vivo ...
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2025-03-31Berichte und sonstige TexteDirekte Krankheitskosten - Alle Altersgruppen Ergebnisse der Diabetes-Surveilance 2015-2024Der hier dargestellte Indikator (Kennzahl) ist Teil des Indikatorensets der Diabetes-Surveillance (Forschungsprojekt am Robert Koch-Institut 2015-2024) mit insgesamt 40 definierten Indikatoren beziehungsweise Indikatorgruppen. ...
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2025-03-31Berichte und sonstige TexteDisability-adjusted life years (DALY) – Alle Altersgruppen Ergebnisse der Diabetes-Surveillance 2015 – 2024Der hier dargestellte Indikator (Kennzahl) ist Teil des Indikatorensets der Diabetes-Surveillance (Forschungsprojekt am Robert Koch-Institut 2015-2024) mit insgesamt 40 definierten Indikatoren beziehungsweise Indikatorgruppen. ...
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2025-03-31Berichte und sonstige TexteDisability-adjusted life years – All age groups Results of the Diabetes Surveillance 2015 – 2024The indicator (key figure) presented here is part of the Diabetes Surveillance indicator set (research project at the Robert Koch Institute 2015 – 2024) with a total of 40 defined indicators or indicator groups. In addition ...
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2014-04-01ZeitschriftenartikelDisagreement of the two oscillometric blood pressure measurement devices, Datascope Accutorr Plus and Omron HEM-705CP II, and bidirectional conversion of blood pressure values. Objective(s): Oscillometric blood pressure (BP) measurement devices frequently replace the standard mercury sphygmomanometer. Comparisons of oscillometric devices are rare, but their agreement is important to ensure ...
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2007-09-06ZeitschriftenartikelDiscovery of herpesviruses in multi-infected primates using locked nucleic acids (LNA) and a bigenic PCR approach Targeting the highly conserved herpes DNA polymerase (DPOL) gene with PCR using panherpes degenerate primers is a powerful tool to universally detect unknown herpesviruses. However, vertebrate hosts are often infected with ...
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2021-03-15ZeitschriftenartikelDiscovery of Novel Herpes Simplexviruses in Wild Gorillas, Bonobos, and Chimpanzees Supports Zoonotic Origin of HSV-2 Viruses closely related to human pathogens can reveal the origins of human infectious diseases. Human herpes simplexvirus type 1 (HSV-1) and type 2 (HSV-2) are hypothesized to have arisen via host-virus codivergence and ...
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2014-12-19ZeitschriftenartikelDiscrete and overlapping functions of peptidoglycan synthases in growth, cell division and virulence of Listeria monocytogenes Upon ingestion of contaminated food, Listeria monocytogenes can cause serious infections in humans that are normally treated with β-lactam antibiotics. These target Listeria's five high molecular weight penicillin-binding ...
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2021-04-20ZeitschriftenartikelDiscrete choice experiment to determine preferences of decision-makers in healthcare for different formats of rapid reviews Background Time-saving formats of evidence syntheses have been developed to fulfill healthcare policymakers’ demands for timely evidence-based information. A discrete choice experiment (DCE) with decision-makers and ...
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2020-05-22ZeitschriftenartikelDiscrete populations of isotype-switched memory B lymphocytes are maintained in murine spleen and bone marrow At present, it is not clear how memory B lymphocytes are maintained over time, and whetheronly as circulating cells or also residing in particular tissues. Here we describe distinctpopulations of isotype-switched memory B ...
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2021-11-18ZeitschriftenartikelDiscrimination of SARS-CoV-2 Infections From Other Viral Respiratory Infections by Scent Detection Dogs Background: Testing of possibly infected individuals remains cornerstone of containing the spread of SARS-CoV-2. Detection dogs could contribute to mass screening. Previous research demonstrated canines' ability to detect ...
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2018-04-10ZeitschriftenartikelDisease detection, epidemiology and outbreak response: the digital future of public health practice Inequalities persist when it comes to the attention, resource allocation and political prioritization, and provision of appropriate, adequate, and timely health interventions to populations in need. Set against a complex ...
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2023-02-10ZeitschriftenartikelDisease severity in hospitalized COVID-19 patients: comparing routine surveillance with cohort data from the LEOSS study in 2020 in Germany Introduction Studies investigating risk factors for severe COVID-19 often lack information on the representativeness of the study population. Here, we investigate factors associated with severe COVID-19 and compare the ...
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2021-11-12Berichte und sonstige TexteDisease severity of the first COVID-19 wave in Germany using reporting data from the national notification system As of December 31, 2019, initial reports circulated internationally of an unusual cluster of pneumonia of unknown cause in China. By the end of January 2020, the virus affected Germany with the first case confirmed on ...
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2021-05-14ZeitschriftenartikelDisease surveillance for the COVID-19 era: time for bold changes The COVID-19 pandemic has exposed weaknesses in disease surveillance in nearly all countries. Early identification of COVID-19 cases and clusters for rapid containment was hampered by inadequate diagnostic capacity, ...
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2016-01-04ZeitschriftenartikelDisease Transmission by Misfolded Prion-Protein Isoforms, Prion-Like Amyloids, Functional Amyloids and the Central Dogma In 1982, the term “prions” (proteinaceous infectious particles) was coined to specify a new principle of infection. A misfolded isoform of a cellular protein has been described as the causative agent of a fatal neurodegenerative ...
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2011-12-28ZeitschriftenartikelDiseases and causes of death in European bats: dynamics in disease susceptibility and infection rates. Background: Bats receive increasing attention in infectious disease studies, because of their well recognized status as reservoir species for various infectious agents. This is even more important, as bats with their ...
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2020-02-05ZeitschriftenartikelDisentangling outbreaks using whole-genome sequencing: concurrent multistate outbreaks of Salmonella Kottbus in Germany, 2017 In June 2017, an outbreak of Salmonella Kottbus infection was suspected in Germany. We investigated the outbreak with whole-genome sequencing (WGS) and a case–control study. Forty-six isolates from 69 cases were subtyped. ...