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Anzeige der Publikationen 3913-3932 von 11403
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2020-12-24ZeitschriftenartikelFirst detection of bat-borne Issyk-Kul virus in Europe Bats have been gaining attention as potential reservoir hosts of numerous viruses pathogenic to animals and man. Issyk-Kul virus, a member of the family Nairoviridae, was first isolated in the 1970s from vespertilionid ...
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2015-09-24ZeitschriftenartikelFirst Draft Genome Sequence of Balamuthia mandrillaris, the Causative Agent of Amoebic Encephalitis The free-living amoeba Balamuthia mandrillaris is a rare but highly lethal agent of amoebic encephalitis in humans and many other mammalian species. Here, we announce the first draft genome sequence of the original 1990 ...
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2013-01-18ZeitschriftenartikelFirst indication for a functional CRISPR/Cas system in Francisella tularensis Francisella tularensis is a zoonotic agent and the subspecies novicida is proposed to be a water-associated bacterium. The intracellular pathogen F. tularensis causes tularemia in humans and is known for its potential to ...
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2007-07-03ZeitschriftenartikelFirst international diagnostic accuracy study for the serological detection of West Nile virus infection Background: The diagnosis of an acute or convalescent West Nile (WN) virus infection can be confirmed by various serological assays such as enzyme immunoassay (EIA), immunofluorescence assay (IFA), or neutralisation test ...
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2012-06-26ZeitschriftenartikelFirst International External Quality Assessment of Molecular Detection of Crimean-Congo Hemorrhagic Fever Virus Crimean-Congo hemorrhagic fever (CCHF) is a zoonosis caused by a Nairovirus of the family Bunyaviridae. Infection is transmitted to humans mostly by Hyalomma ticks and also by direct contact with the blood or tissues of ...
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2015-05-30ZeitschriftenartikelFirst international external quality assessment of molecular diagnostics for Mers-CoV Background: Since the discovery of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, diagnostic protocols were quickly published and deployed globally. Objectives: We set out to assess the quality of ...
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2012-05-03ZeitschriftenartikelFirst International External Quality Assessment Study on Molecular and Serological Methods for Yellow Fever Diagnosis Objective: We describe an external quality assurance (EQA) study designed to assess the efficiency and accurateness of molecular and serological methods used by expert laboratories performing YF diagnosis. Study Design: ...
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2014-05-01ZeitschriftenartikelFirst Line Treatment Response in Patients with Transmitted HIV Drug Resistance and Well Defined Time Point of HIV Infection: Updated Results from the German HIV-1 Seroconverter Study Background: Transmission of drug-resistant HIV-1 (TDR) can impair the virologic response to antiretroviral combination therapy. Aim of the study was to assess the impact of TDR on treatment success of resistance test-guided ...
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2014-06-25ZeitschriftenartikelFirst report of a Chinese strain of coxsackie B3 virus infection in a newborn in Germany in 2011: a case report Introduction: Enteroviruses commonly encounter babies and children and infections present in a wide variety of symptoms ranging from asymptomatic infection, benign illness, and aseptic meningitis, hand-foot-and-mouth ...
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2012-07-05ZeitschriftenartikelFirst report of sandfly fever virus infection imported from Malta into Switzerland, October 2011 We report the first documented cases of sandfly fever virus infection in travellers returning from Malta to Switzerland in autumn 2011. These cases illustrate the importance of considering sandfly-borne viral infection in ...
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2017-07-15ZeitschriftenartikelFirst report of two complete Clostridium chauvoei genome sequences and detailed in silico genome analysis Clostridium (C.) chauvoei is a Gram-positive, spore forming, anaerobic bacterium. It causes black leg in ruminants, a typically fatal histotoxic myonecrosis. High quality circular genome sequences were generated for the ...
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2018-06-20ZeitschriftenartikelFirst results from the study ‘Disease knowledge and information needs - Diabetes mellitus (2017)’ Very little research has been undertaken into what people in Germany know about diabetes, the information they may require about the condition, where they look for such information and how they rate the information ...
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2021-06-18ZeitschriftenartikelFirst Serological Evidence of Crimean-Congo Hemorrhagic Fever Virus and Rift Valley Fever Virus in Ruminants in Tunisia Crimean-Congo hemorrhagic fever virus (CCHFV, Nairoviridae family) and Rift Valley fever virus (RVFV, Phenuiviridae family) are zoonotic vector-borne pathogens with clinical relevance worldwide. Our study aimed to determine ...
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2019-06-12ZeitschriftenartikelFirst-line tuberculosis drug resistance patterns and associated risk factors in Germany, 2008-2017 Background Drug-resistant tuberculosis (TB), especially multidrug-resistant TB (MDR-TB), poses a threat to public health. While standard surveillance focuses on Rifampicin and/or Isoniazid resistance, little is known about ...
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2013-07-01ZeitschriftenartikelFitness costs of various mobile genetic elements in Enterococcus faecium and Enterococcus faecalis Objectives: To determine the fitness effects of various mobile genetic elements (MGEs) in Enterococcus faecium and Enterococcus faecalis when newly acquired. We also tested the hypothesis that the biological cost of ...
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2013-08-28Berichte und sonstige TexteFizzy drinks, juices etc. The consumption of beverages containing sugars in GermanThis issue is about the consumption of beverages containing sugar, like soft drinks and fruit juices in the German population. Martina Rabenberg and Gert Mensink try to answer the following questions: Is there a difference ...
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2010-12-09ZeitschriftenartikelFlagellin genes of Yersinia enterocolitica biotype 1A: playground of evolution towards novel flagellin functions Yersinia enterocolitica strain 8081, representing the high-pathogenic biotype 1B, harbours three flagellin genes arranged in tandem in the order fliC3, fliC, fliC2. The genes are organized monocistronic but coordinately ...
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2018-07-11ZeitschriftenartikelFlexible decision-making in grooming partner choice in sooty mangabeys and chimpanzees Living in permanent social groups forces animals to make decisions about when, how and with whom to interact, requiring decisions to be made that integrate multiple sources of information. Changing social environments can ...
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2020-12-07ZeitschriftenartikelFLEXIQuant-LF to quantify protein modification extent in label-free proteomics data Improvements in LC-MS/MS methods and technology have enabled the identification of thousands of modified peptides in a single experiment. However, protein regulation by post-translational modifications (PTMs) is not binary, ...
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2012-08-05ZeitschriftenartikelFliA expression analysis and influence of the regulatory proteins RpoN, FleQ and FliA on virulence and in vivo fitness in Legionella pneumophila In Legionella pneumophila, the regulation of the flagellum and the expression of virulence traits are linked. FleQ, RpoN and FliA are the major regulators of the flagellar regulon. We demonstrated here that all three ...