Browsing by Title
Now showing items 4512-4531 of 13217
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2010-03-29Teil eines BuchesExperimentelle Studien über die künstliche Abschwächung der Milzbrandbazillen und Milzbrandinfektion durch Fütterung
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2018-05-29ZeitschriftenartikelExpertise des Robert Koch-Instituts für den ersten Präventions- bericht: Hintergrund, Ziele und Herangehensweise
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2018-05-29ZeitschriftenartikelExpertise of the Robert Koch Institute for the first prevention report: background, aims and approach
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2022-08-10ZeitschriftenartikelExploratory study of the underutilization of CTSA module services Background/Objective: The Clinical and Translational Science Award (CTSA) program aims to enhance the quality, efficiency, and impact of translation from discovery to interventions that improve human health. CTSA program ...
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2021-02-02ZeitschriftenartikelExploring how Syrian women manage their health after migration to Germany: results of a qualitative study Background In the recent years, the number of Syrians living in Germany increased drastically due to the massive displacement caused by the Syrian conflict. Syrian migrant women in Germany are challenged by both the ...
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2023-09-22ZeitschriftenartikelExploring HPV vaccine knowledge, attitudes, barriers and information sources among parents, health professionals and teachers in Kazakhstan: a mixed-methods study protocol Introduction: Human papillomavirus (HPV) is a prevalent sexually transmitted infection linked to certain types of malignant neoplasms, notably cervical cancer (CC). In Kazakhstan, a high prevalence of high oncogenic HPV ...
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2022-08-05ZeitschriftenartikelExploring pandemic-related health literacy among adolescents in Germany: a focus group study Background Health literacy enables people to cope efficiently with health threats, such as the COVID-19 pandemic. However, little is known about health literacy among adolescents in general and especially in the context ...
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2024-05-03ZeitschriftenartikelExploring the effect of clinical case definitions on influenza vaccine effectiveness estimation at primary care level: Results from the end-of-season 2022–23 VEBIS multicentre study in Europe Background: Within influenza vaccine effectiveness (VE) studies at primary care level with a laboratory-confirmed outcome, clinical case definitions for recruitment of patients can vary. We used the 2022–23 VEBIS primary ...
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2018-04-16ZeitschriftenartikelExploring the effect of previous inactivated influenza vaccination on seasonal influenza vaccine effectiveness against medically attended influenza: Results of the European I‐MOVE multicentre test‐negative case‐control study, 2011/2012‐2016/2017 Background Results of previous influenza vaccination effects on current season influenza vaccine effectiveness (VE) are inconsistent. Objectives To explore previous influenza vaccination effects on current season VE ...
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2009-04-24ZeitschriftenartikelExploring the functional interaction between POSH and ALIX and the relevance to HIV-1 release Background: The ALG2-interacting protein X (ALIX)/AIP1 is an adaptor protein with multiple functions in intracellular protein trafficking that plays a central role in the biogenesis of enveloped viruses. The ubiquitin ...
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2016-11-15ZeitschriftenartikelExposure Patterns Driving Ebola Transmission in West Africa: A Retrospective Observational Study Background: The ongoing West African Ebola epidemic began in December 2013 in Guinea, probably from a single zoonotic introduction. As a result of ineffective initial control efforts, an Ebola outbreak of unprecedented ...
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2010-08-23BachelorarbeitExpression and purification of the primate foamy virus transmembrane envelope protein Seit dem Nachweis breit neutralisierender Antikörper (bNAb), welche von HIV-infizierten Menschen gebildet werden können, konzentrieren sich viele Ansätze auf die Induktion solcher Antikörper zur Entwicklung eines HIV ...
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2003-01-01ZeitschriftenartikelExpression of ICOS In Vivo Defines CD4+ Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10 The studies performed to date analyzed the overall participation of the inducible costimulator (ICOS) in model diseases, but did not yield information on the nature and function of ICOS-expressing T cells in vivo. We ...
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2020-10-06ZeitschriftenartikelExpression of in vivo biotinylated recombinant antigens SAG1 and SAG2A from Toxoplasma gondii for improved seroepidemiological bead-based multiplex assays Background Few bead-based multiplex assays have been described that detect antibodies against the protozoan parasite Toxoplasma gondii in large-scale seroepidemiological surveys. Moreover, each multiplex assay has ...
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2023-01-06ZeitschriftenartikelExpression of virulence and antimicrobial related proteins in Burkholderia mallei and Burkholderia pseudomallei Background: Burkholderia mallei and Burkholderia pseudomallei are both potential biological threat agents. Melioidosis caused by B. pseudomallei is endemic in Southeast Asia and Northern Australia, while glanders caused ...
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2012-07-18ZeitschriftenartikelExpression of XCR1 characterizes the Batf3-dependent lineage of dendritic cells capable of antigen cross-presentation Cross-presentation of antigen by dendritic cells (DCs) to CD8+ T cells is a fundamentally important mechanism in the defense against pathogens and tumors. Due to the lack of an appropriate lineage marker, cross-presenting ...
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2009-06-01DiplomarbeitExpression rekombinanter, von HIV-1 gp41 abgeleiteter Proteine für die Analyse der Immunpathogenese Zur Etablierung eines Endotoxin-freien Bacillus megaterium Produktionssystems wurden zehn mittels PCR amplifizierte, von HIV-1 g41 abgeleitete Fragmente hergestellt und in transformations-kompetente B. megaterium Protoplasten ...
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2018-08-09BachelorarbeitExpression und Analyse retroviraler immunsuppressiver Doma nen auf humanen Zellen Eine Vielzahl von Retroviren sind in der Lage, das Immunsystem des Wirtes durch verschiedene Mechanismen zu beeinflussen. Die isu-Domäne als ein Teil der retroviralen TM-Proteine p15E (PERV, MuLV), sowie gp41 (HIV-1) ...
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2006-09-01DissertationExpression und biologische Funktion von humanen endogenen Retroviren (HERVs), insbesondere von HERV-K Daten des humanen Genomprojektes zeigen, dass ca. 8% des gesamten humanen Genoms aus retroviralen Sequenzen besteht. Der überwiegende Teil dieser Proviren ist aufgrund verschiedener Mutationen defekt. Im Gegensatz zu ...
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2005-09-01DiplomarbeitExpression von porzinen endogenen Retroviren in metastasierenden Melanomen und Melanomzelllinien von Troll Schweinen Porzine endogene Retroviren (PERVs) sind im Genom aller Schweine integriert. Ihre Expression in normalen porzinen Geweben sowie in Tumoren und ihre biologische Rolle ist bisher nicht ausführlich untersucht worden. Im ...