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Now showing items 7434-7453 of 12057
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2017-07-13ZeitschriftenartikelProjekt zur Schließung von Impflücken bei Schülern der 6. Klassenstufe und Lehrern im Landkreis Görlitz (Sachsen) Seit dem Jahr 2013 werden im Landkreis Görlitz bei Kindern der 6. Klassenstufe die Impfpässe jährlich kontrolliert.1,2,3 Im Jahr 2016 erfolgte dies vom 23. Mai 2016 – 27. Mai 2016 am Gesundheitsamt (GA) des Landkreises ...
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2020-04-19ZeitschriftenartikelPromoter activity of Merkel cell Polyomavirus variants in human dermal fibroblasts and a Merkel cell carcinoma cell line Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts believed to be the natural host cell. However, this virus is the major ...
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2021-08-20ZeitschriftenartikelPropagation of CJD Prions in Primary Murine Glia Cells Expressing Human PrPc There are various existing cell models for the propagation of animal prions. However, in vitro propagation of human prions has been a long-standing challenge. This study presents the establishment of a long-term primary ...
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2006-09-01ZeitschriftenartikelPropagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters As is known from various animal models, the spread of agents causing transmissible spongiform encephalopathies (TSE) after peripheral infection affects peripheral nerves before reaching the central nervous system (CNS) ...
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2006-12-21ZeitschriftenartikelPropagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters As is known from various animal models, the spread of agents causing transmissible spongiform encephalopathies (TSE) after peripheral infection affects peripheral nerves before reaching the central nervous system (CNS) and ...
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2021-04-30ZeitschriftenartikelProphylaxis and treatment of influenza: options, antiviral susceptibility, and existing recommendations Influenza viruses of types A and B attack 5–10% of adults and 20–30% of children, thereby causing millions of acute respiratory infections in Germany annually. A significant number of these infections are associated with ...
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2011-07-20ZeitschriftenartikelProspective genomic characterization of the German enterohemorrhagic escherichia coli O104:H4 outbreak by rapid next generation sequencing technology. An ongoing outbreak of exceptionally virulent Shiga toxin (Stx)-producing Escherichia coli O104:H4 centered in Germany, has caused over 830 cases of hemolytic uremic syndrome (HUS) and 46 deaths since May 2011. Serotype ...
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2012-05-31ZeitschriftenartikelProspective hospital-based case–control study to assess the effectiveness of pandemic influenza A(H1N1)pdm09 vaccination and risk factors for hospitalization in 2009–2010 using matched hospital and test-negative controls Background: We performed a case–control study to estimate vaccine effectiveness (VE) for prevention of hospitalization due to pandemic influenza A(H1N1)pdm09 (pH1N1) and to identify risk factors for pH1N1 and acute ...
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2017-02-08ZeitschriftenartikelProspective multicenter German study on pulmonary colonization with Scedosporium /Lomentospora species in cystic fibrosis: Epidemiology and new association factors Background: An increasing rate of respiratory colonization and infection in cystic fibrosis (CF) is caused by fungi of the Scedosporium apiospermum species complex or Lomentospora prolificans (Sac-Lp). These fungi rank ...
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2024-08StudienarbeitProspektive Erhebung zur Veränderung der bevorzugten Therapieform beim low risk und favourable intermediate risk Prostatakarzinom in Deutschland (67a-Studie) Die vorliegende Studie soll als epidemiologische Aufarbeitung die tatsächliche Veränderung der bevorzugten Therapieform beim low risk Prostatakarzinom dienen. Um das komplette Bild der Situation in Deutschland zu analysieren, ...
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2022-09-04ZeitschriftenartikelProtecting great apes from disease: Compliance with measures to reduce anthroponotic disease transmission Das Auftreten von Infektionskrankheiten wie COVID-19 hat Auswirkungen auf Lebensunterhaltstrategien und auf Naturschutzmaßnahmen, die von der Interaktion zwischen Mensch und Wildtieren abhängen, wie z. B. Wildtiertourismus ...
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2016-05-24Berichte und sonstige TexteProtecting Health – Assessing Risks Who we are? What we look back on? What we do and will do?
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2012-12-11ZeitschriftenartikelProtecting society: Biological security and dual-use dilemma in the life sciences-status quo and options for the future Life science research is a main pillar of health care; major discoveries have considerably improved life expectancy and quality of life. However, research, technologies and materials that can be used for good can also be ...
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2017-07-12ZeitschriftenartikelProtection of farm goats by combinations of recombinant peptides and formalin inactivated spores from a lethal Bacillus anthracis challenge under field conditions Background: Bacillus (B.) anthracis, the causal agent of anthrax, is effectively controlled by the Sterne live spore vaccine (34F2) in animals. However, live spore vaccines are not suitable for simultaneous vaccination ...
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2009-10-18ZeitschriftenartikelProtective measures and H5N1-seroprevalence among personnel tasked with bird collection during an outbreak of avian influenza A/H5N1 in wild birds, Ruegen, Germany, 2006 Background: In Germany, the first outbreak of highly pathogenic avian influenza A/H5N1 occurred among wild birds on the island of Ruegen between February and April 2006. The aim of this study was to investigate the ...
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2013-02-28ZeitschriftenartikelProtein function prediction using domain families Here we assessed the use of domain families for predicting the functions of whole proteins. These 'functional families' (FunFams) were derived using a protocol that combines sequence clustering with supervised cluster ...
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2012-12-21ZeitschriftenartikelProtein-Protein Interaction Domains of Bacillus subtilis DivIVA DivIVA proteins are curvature-sensitive membrane binding proteins that recruit other proteins to the poles and the division septum. They consist of a conserved N-terminal lipid binding domain fused to a less conserved ...
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2011-08-01ZeitschriftenartikelProteome analysis of vaccinia virus IHD-W-infected HEK 293 cells with 2-dimensional gel electrophoresis and MALDI-PSD-TOF MS of on solid phase support N-terminally sulfonated peptides Background: Despite the successful eradication of smallpox by the WHO-led vaccination programme, pox virus infections remain a considerable health threat. The possible use of smallpox as a bioterrorism agent as well as ...
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2015-11-02ZeitschriftenartikelProteomic analysis of protein carbonylation: a useful tool to unravel nanoparticle toxicity mechanisms Background: Oxidative stress, a commonly used paradigm to explain nanoparticle (NP)-induced toxicity, results from an imbalance between reactive oxygen species (ROS) generation and detoxification. As one consequence, ...
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2014-12-15ZeitschriftenartikelProtocol for Metagenomic Virus Detection in Clinical Specimens Sixty percent of emerging viruses have a zoonotic origin, making transmission from animals a major threat to public health. Prompt identification and analysis of these pathogens are indispensable to taking action toward ...