Auflistung nach Schlagwort "Viral Proteins/metabolism"
Anzeige der Publikationen 1-7 von 7
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2011-04-06ZeitschriftenartikelCytomegalovirus e127 protein interacts with the inhibitory CD200 receptor. CD200 is a cell surface glycoprotein that binds an inhibitory receptor (CD200R) on myeloid cells. CD200 orthologues are present in many species of virus, and we show that the rat cytomegalovirus CD200 orthologue (e127) is ...
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2015-05-29ZeitschriftenartikelEvidence for a Novel Mechanism of Influenza Virus-Induced Type I Interferon Expression by a Defective RNA-Encoded Protein Influenza A virus (IAV) defective RNAs are generated as byproducts of error-prone viral RNA replication. They are commonly derived from the larger segments of the viral genome and harbor deletions of various sizes resulting ...
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2009-06-12ZeitschriftenartikelInfluenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR Activation of the latent kinase PKR is a potent innate defense reaction of vertebrate cells towards viral infections, which is triggered by recognition of viral double-stranded (ds) RNA and results in a translational ...
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2010-08-11ZeitschriftenartikelMumps virus small hydrophobic protein targets ataxin-1 ubiquitin-like interacting protein (ubiquilin 4) The small hydrophobic (SH) protein of mumps virus has been reported to interfere with innate immunity by inhibiting tumour necrosis factor alpha-mediated apoptosis. In a yeast two-hybrid screen we have identified the ...
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2011-10-12ZeitschriftenartikelNo Detection of XMRV in Blood Samples and Tissue Sections from Prostate Cancer Patients in Northern Europe. Background: We recently published the rare detection of xenotropic murine leukemia virus-related virus (XMRV) (1/105) in prostate cancer (PCA) tissue of patients in Northern Europe by PCR. The controversial discussion ...
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2013-08-07ZeitschriftenartikelThe Transmembrane Protein of the Human Endogenous Retrovirus - K (HERV-K) Modulates Cytokine Release and Gene Expression Numerous copies of endogenous retroviruses are present in the genome of mammals including man. Although most of them are defective, some, e.g., the human endogenous retroviruses HERV-K, were found to be expressed under ...
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2012-10-03ZeitschriftenartikelTreatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...