TY - GEN T1 - Symptomatic Illness and Low CD4 Cell Count at HIV Seroconversion as Markers of Severe Primary HIV Infection AU - Lodi, Sara AU - Fisher, Martin AU - Phillips, Andrew AU - Luca, Andrea de AU - Ghosn, Jade AU - Malyuta, Ruslan AU - Zangerle, Robert AU - Moreno, Santiago AU - Vanhems, Philippe AU - Boufassa, Faroudy AU - Guiguet, Marguerite AU - Porter, Kholoud AB - Background: The risk/benefit of initiating ART in primary HIV infection (PHI) is unclear. The benefits are more likely to outweigh the risks in patients with severe PHI. An accepted definition of severe PHI is, however, lacking. Methods: CASCADE patients with HIV test interval KW - Humans KW - HIV-1 KW - Female KW - Male KW - CD4 Lymphocyte Count KW - Biological Markers/blood KW - Disease-Free Survival KW - HIV Seropositivity/blood KW - HIV Seropositivity/drug therapy KW - HIV Seropositivity/immunology KW - HIV Seropositivity/mortality KW - HIV Seropositivity/pathology KW - Models Biological KW - Severity of Illness Index KW - Survival Rate KW - 610 Medizin PY - 2013 LA - eng PB - Robert Koch-Institut, Infektionsepidemiologie VL - 8 IS - 11 DO - 10.1371/journal.pone.0078642 ER -