TY - JOUR T1 - Large variation in ESBL-producing Escherichia coli carriers in six European countries including Russia AU - Ny, Sofia AU - Kozlov, Roman AU - Dumpis, Uga AU - Edquist, Petra AU - Gröndahl-Yli-Hannuksela, Kirsi AU - Kling, Anna-Maria AU - Lis, Danuta O. AU - Lübbert, Christoph AU - Pomorska-Wesołowska, Monika AU - Palagin, Ivan AU - Vilde, Aija AU - Vuopio, Jaana AU - Walter, Jan AU - Tegmark Wisell, Karin AU - NoDARS ESBL-carrier working group AB - We investigated the faecal carriage prevalence of extended-spectrum β-lactamase production in Escherichia coli (EP-EC) and/or Klebsiella pneumoniae (EP-KP) and risk factors associated with carriage among adult study subjects in Finland, Germany, Latvia, Poland, Russia and Sweden (partner countries). The aim was to get indicative data on the prevalence of ESBL-carriage in specific populations in the region. Faecal samples were collected from four study populations and screened on ChromID-ESBL and ChromID-OXA-48 plates. Positive isolates were further characterised phenotypically. Our results show a large variation in carrier prevalence ranging from 1.6% in Latvia to 23.2% in Russia for EP-EC. For the other partner countries, the prevalence of EP-EC were in increasing numbers, 2.3% for Germany, 4.7% for Finland, 6.6% for Sweden, 8.0% for Poland and 8.1% for all partner countries in total. Carriers of EP-KP were identified only in Finland, Russia and Sweden, and the prevalence was < 2% in each of these countries. No carriers of carbapenemase-producing isolates were identified. This is the first study reporting prevalence of carriers (excluding traveller studies) for Finland, Latvia, Poland and Russia. It contributes with important information regarding the prevalence of EP-EC and EP-KP carriage in regions where studies on carriers are limited. KW - ESBL KW - Asymptomatic carriage KW - Antibiotic resistance KW - E. coli KW - K. pneumoniae Europe and Russia KW - 610 Medizin und Gesundheit PY - 2018 LA - eng PB - Robert Koch-Institut JO - European Journal of Clinical Microbiology & Infectious Diseases VL - 37 IS - 12 SP - 2347 EP - 2354 DO - 10.1007/s10096-018-3382-8 ER -