TY - GEN T1 - Pandemic influenza A(H1N1) 2009 breakthrough infections and estimates of vaccine effectiveness in Germany 2009-2010. AU - Wichmann, Ole AU - Stöcker, Petra AU - Poggensee, Gabriele AU - Altmann, Doris AU - Walter, Dietmar AU - Hellenbrand, Wiebke AU - Krause, Gérard AU - Eckmanns, Tim AB - During the 2009 influenza pandemic, a monovalent AS03-adjuvanted vaccine was almost exclusively used in Germany for immunisation against the 2009 pandemic influenza A(H1N1) virus. One-dose vaccination was recommended for all age groups. We applied the screening method for the rapid assessment of vaccine effectiveness (VE) based on reported data of vaccinated and unvaccinated pandemic influenza cases and vaccination coverage estimates. Preliminary results demonstrate excellent VE in persons aged 14-59 years (96.8%; 95% confidence interval (CI): 95.2-97.9) and moderately high VE in those 60 years or older (83.3%; 95% CI: 71.0-90.5). KW - Adolescent KW - Human/epidemiology KW - Human/prevention & control KW - Humans KW - Disease Outbreaks KW - Germany/epidemiology KW - Middle Aged KW - Adult KW - Interviews as Topic KW - Influenza A Virus KW - Influenza KW - Treatment Outcome KW - Young Adult KW - H1N1 Subtype/isolation & purification KW - Influenza Vaccines KW - 610 Medizin PY - 2010 LA - eng PB - Robert Koch-Institut VL - 15 IS - 18 DO - http://dx.doi.org/10.25646/566 ER -