TY - JOUR T1 - Impact of sex and gender on COVID-19 outcomes in Europe AU - Gebhard, Catherine AU - Regitz-Zagrosek, Vera AU - Neuhauser, Hannelore K. AU - Morgan, Rosemary AU - Klein, Sabra L. AB - Emerging evidence from China suggests that coronavirus disease 2019 (COVID-19) is deadlier forinfected men than women with a 2.8% fatality rate being reported in Chinese men versus 1.7% in women. Further,sex-disaggregated data for COVID-19 in several European countries show a similar number of cases between thesexes, but more severe outcomes in aged men. Case fatality is highest in men with pre-existing cardiovascularconditions. The mechanisms accounting for the reduced case fatality rate in women are currently unclear but mayoffer potential to develop novel risk stratification tools and therapeutic options for women and men. KW - Gender KW - Sex KW - COVID-19 KW - Renin angiotensin aldosterone system KW - Immune system KW - 610 Medizin und Gesundheit PY - 2020 LA - eng PB - Robert Koch-Institut JO - Biology of Sex Differences IS - 11 DO - 10.1186/s13293-020-00304-9 ER -