TY - JOUR T1 - Excellent performance of CHROMagarTM LIN-R to selectively screen for linezolid-resistant enterococci and staphylococci AU - Layer, Franziska AU - Weber, Robert E. AU - Fleige, Carola AU - Strommenger, Birgit AU - Cuny, Christiane AU - Werner, Guido AB - The increasing number of nosocomial pathogens with resistances against last resort antibiotics like linezolid leads to a pressing need for the reliable detection of these drug-resistant bacteria. National guidelines on infection prevention, e.g., in Germany, have already recommend screening for linezolid-resistant bacteria, although a corresponding screening agar medium has not been provided. In this study we analyzed the performance and reliability of a commercial, chromogenic linezolid screening agar. The medium was capable to predict more than a hundred linezolid-resistant isolates of E. faecium, E. faecalis, S. aureus, S. epidermidis, and S. hominis with excellent sensitivity and specificity. All isolates were collected at the National Reference Centre between 2010 and 2020. KW - cfr KW - optrA KW - poxtA KW - Enterococcus KW - Staphylococcus KW - 610 Medizin und Gesundheit PY - 2020 LA - eng PB - Robert Koch-Institut JO - Diagnostic Microbiology and Infectious Disease VL - 99 IS - 4 DO - 10.1016/j.diagmicrobio.2020.115301 ER -