TY - JOUR T1 - Real-time monitoring shows substantial excess all-cause mortality during second wave of COVID-19 in Europe, October to December 2020 AU - Nørgaard, Sarah K. AU - Vestergaard, Lasse S. AU - Nielsen, Jens AU - Richter, Lukas AU - Schmid, Daniela AU - Bustos, Natalia AU - Braye, Toon AU - Athanasiadou, Maria AU - Lytras, Theodore AU - Denissov, Gleb AU - Veideman, Tatjana AU - Luomala, Oskari AU - Möttönen, Teemu AU - Fouillet, Anne AU - Caserio-Schönemann, Céline AU - an der Heiden, Matthias AU - Uphoff, Helmut AU - Gkolfinopoulou, Kassiani AU - Bobvos, Janos AU - Paldy, Anna AU - Rotem, Naama AU - Kornilenko, Irene AU - Domegan, Lisa AU - O’Donnell, Joan AU - De Donato, Francesca AU - Scortichini, Matteo AU - Hoffmann, Patrick AU - Velez, Telma AU - England, Kathleen AU - Calleja, Neville AU - van Asten, Liselotte AU - Stoeldraijer, Lenny AU - White, Richard A. AU - Paulsen, Trine H. AU - da Silva, Susana P. AU - Rodrigues, Ana P. AU - Klepac, Petra AU - Zaletel, Metka AU - Fafangel, Mario AU - Larrauri, Amparo AU - León, Inmaculada AU - Farah, Ahmed AU - Galanis, Ilias AU - Junker, Christoph AU - Perisa, Damir AU - Sinnathamby, Mary AU - Andrews, Nick AU - O'Doherty, Mark G. AU - Irwin, David AU - Kennedy, Sharon AU - McMenamin, Jim AU - Adlhoch, Cornelia AU - Bundle, Nick AU - Penttinen, Pasi AU - Pukkila, Jukka AU - Pebody, Richard AU - Krause, Tyra G. AU - Mølbak, Kåre AB - The coronavirus disease (COVID-19) global pandemic is ongoing, with Europe and the Americas the current epicentres of transmission. As at 1 January, 2021, over 82 million cases and 1.8 million deaths have been reported globally [1,2]. In Europe alone, the number of cases reported has now passed 26 million, with over 580,000 laboratory-confirmed COVID-19 deaths [3,4]. As many COVID-19 cases and deaths may not be confirmed by virological testing, and as the pandemic causes a range of indirect and collateral harms, the officially reported figures of laboratory-confirmed COVID-19 cases and deaths represent only a part of the total disease, mortality and overall public health burden associated with the pandemic. Here we report some noteworthy estimates of a marked increase in excess all-cause mortality in Europe coinciding with a steep second wave of COVID-19 in many countries since September 2020. KW - 610 Medizin und Gesundheit PY - 2021 LA - eng PB - Robert Koch-Institut JO - Eurosurveillance VL - 26 IS - 2 SP - 1 EP - 5 DO - https://doi.org/10.2807/1560-7917.ES.2021.26.1.2002023 ER -