TY - JOUR T1 - Burden of non-communicable disease studies in Europe: a systematic review of data sources and methodological choices AU - Charalampous, Periklis AU - Gorasso, Vanessa AU - Plass, Dietrich AU - Pires, Sara M. AU - von der Lippe, Elena AU - Mereke, Alibek AU - Idavain, Jane AU - Kissimova-Skarbek, Katarzyna AU - Morgado, Joana Nazare AU - Ngwa, Che Henry AU - Noguer, Isabel AU - Padron-Monedero, Alicia AU - Santi-Cano, MarĂ­a Jose AU - Sarmiento, Rodrigo AU - Devleesschauwer, Brecht AU - Haagsma, Juanita A. AU - The COST Action CA18218 Participants AB - Background: Assessment of disability-adjusted life years (DALYs) resulting from non-communicable diseases (NCDs) requires specific calculation methods and input data. The aims of this study were to (i) identify existing NCD burden of disease (BoD) activities in Europe; (ii) collate information on data sources for mortality and morbidity; and (iii) provide an overview of NCD-specific methods for calculating NCD DALYs. Methods: NCD BoD studies were systematically searched in international electronic literature databases and in grey literature. We included all BoD studies that used the DALY metric to quantify the health impact of one or more NCDs in countries belonging to the European Region. Results: A total of 163 BoD studies were retained: 96 (59%) were single-country or sub-national studies and 67 (41%) considered more than one country. Of the single-country studies, 29 (30%) consisted of secondary analyses using existing Global Burden of Disease (GBD) results. Mortality data were mainly derived (49%) from vital statistics. Morbidity data were frequently (40%) drawn from routine administrative and survey datasets, including disease registries and hospital discharge databases. The majority (60%) of national BoD studies reported mortality corrections. Multimorbidity adjustments were performed in 18% of national BoD studies. Conclusion: The number of national NCD BoD assessments across Europe increased over time, driven by an increase in BoD studies that consisted of secondary data analysis of GBD study findings. Ambiguity in reporting the use of NCD-specific BoD methods underlines the need for reporting guidelines of BoD studies to enhance the transparency of NCD BoD estimates across Europe. KW - 610 Medizin und Gesundheit PY - 2022 LA - eng PB - Robert Koch-Institut JO - European Journal of Public Health VL - 32 IS - 2 SP - 289 EP - 296 DO - 10.1093/eurpub/ckab218 ER -