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Now showing items 1101-1110 of 11373

2011-03-24Zeitschriftenartikel

Nuclear versus mitochondrial DNA: evidence for hybridization in colobine monkeys

Roos, Christian; Zinner, Dietmar; Kubatko, Laura S.; Schwarz, Christiane; Yang, Mouyu; Meyer, Dirk; Nash, Stephen D.; Xing, Jinchuan; Batzer, Mark A.; Brameier, Markus; Leendertz, Fabian; Ziegler, Thomas; Perwitasari-Farajallah, Dyah; Nadler, Tilo; Walter, Lutz; Osterholz, Martin

Background: Colobine monkeys constitute a diverse group of primates with major radiations in Africa and Asia. However, phylogenetic relationships among genera are under debate, and recent molecular studies with incomplete ...

2011-02-16Zeitschriftenartikel

Highly conserved serine residue 40 in HIV-1 p6 regulates capsid processing and virus core assembly

Votteler, Jörg; Neumann, Liane; Hahn, Sabine; Hahn, Friedrich; Rauch, Pia; Schmidt, Kerstin; Studtrucker, Nicole; Solbak, Sara MØ; Fossen, Torgils; Henklein, Peter; Ott, David E.; Holland, Gudrun; Bannert, Norbert; Schubert, Ulrich

Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...

2010-03-31Zeitschriftenartikel

Morbiditätsprognosen auf Basis von Bevölkerungsprognosen Welchen Beitrag kann ein Gesundheitsmonitoring leisten?

Nowossadeck, Enno

Die Alterung der Gesellschaft, so wird angenommen, wird zu einem Anstieg der Zahl an erkrankten Menschen beziehungsweise der Neuerkrankungen und zu steigenden Belastungen des Gesundheitssystems führen. Morbiditätsprognosen ...

2010-08-04Zeitschriftenartikel

Virulence Determinants of Avian H5N1 Influenza A Virus in Mammalian and Avian Hosts: Role of the C-Terminal ESEV Motif in the Viral NS1 Protein

Zielecki, Florian; Semmler, Ilia; Kalthoff, Donata; Voss, Daniel; Mauel, Susanne; Gruber, Achim D.; Beer, Martin; Wolff, Thorsten

We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses ...

2010-04-02Zeitschriftenartikel

The Case of Botulinum Toxin in Milk: Experimental Data

Weingart, Oliver G.; Schreiber, Tanja; Mascher, Conny; Pauly, Diana; Dorner, Martin; Berger, Thomas F. H.; Egger, Charlotte; Gessler, Frank; Loessner, Martin J.; Avondet, Marc-André; Dorner, Brigitte

Botulinum neurotoxin (BoNT) is the most toxic substance known to man and the causative agent of botulism. Due to its high toxicity and the availability of the producing organism Clostridium botulinum, BoNT is regarded as ...

2011-03-25Zeitschriftenartikel

Untererfassung von Masern: Eine Evaluation basierend auf Daten aus Nordrhein-Westfalen

Mette, Annedore; Reuss, Annicka; Feig, Marcel; Kappelmayer, Lutz; Siedler, Anette; Eckmanns, Tim; Poggensee, Gabriele

Hintergrund: Die Masernelimination in Europa bis 2015 ist ein WHO-Gesundheitsziel. In Deutschland besteht gemäß Infektionsschutzgesetz (IfSG) eine Meldepflicht für Masernerkrankungen, dennoch geht man von einer Untererfassung ...

2010-03-25Zeitschriftenartikel

Impact of a family-oriented rehabilitation programme on behavioural and emotional problems in healthy siblings of chronically ill children

Besier, Tanja; Hölling, Heike; Schlack, Robert; West, C.; Goldbeck, L.

Objective: To evaluate the impact of a family-oriented inpatient rehabilitation programme on behavioural and emotional problems in healthy siblings of chronically ill children and to assess the association between these ...

2010-09-27Zeitschriftenartikel

Improved Detection of Mutated Human Cytomegalovirus UL97 by Pyrosequencing

Schindele, Birgit; Apelt, Luise; Hofmann, Jörg; Nitsche, Andreas; Michel, Detlef; Voigt, Sebastian; Mertens, Thomas; Ehlers, Bernhard

Ganciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ ...

2011-03-24Zeitschriftenartikel

High time to tackle childhood tuberculosis

2011-04-01Zeitschriftenartikel

"Zielgerade" beim RKI-Gesundheitssurvey DEGS

Kurth, Bärbel-Maria

The Robert Koch Institute is currently conducting the "German Health Interview and Examination Survey for Adults (DEGS)". Its aim is to provide comprehensive data on the health situation of Germany‘s resident population. ...

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