2018-01-29Zeitschriftenartikel
Global ubiquitination analysis reveals extensive modification and proteasomal degradation of cowpox virus proteins, but preservation of viral cores
Grossegesse, Marica; Doellinger, Joerg; Fritsch, Annemarie; Laue, Michael; Piesker, Janett; Schaade, Lars; Nitsche, Andreas
The emergence of Variola virus-like viruses by natural evolution of zoonotic Orthopoxviruses, like Cowpox virus (CPXV), is a global health threat. The proteasome is essential for poxvirus replication, making the viral ...