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2012-05-14Zeitschriftenartikel
Features of “All LNA” Duplexes Showing a New Type of Nucleic Acid Geometry 
Förster, Charlotte; Eichert, André; Oberthür, Dominik; Betzel, Christian; Geßner, Reinhard; Nitsche, Andreas; Fürste, Jens P.
"Locked nucleic acids" (LNAs) belong to the backbone-modified nucleic acid family. The 2'-O,4'-C-methylene-β-D-ribofuranose nucleotides are used for single or multiple substitutions in RNA molecules and thereby introduce ...
2005-02-01Zeitschriftenartikel
Human immunodeficiency virus, hepatitis C and hepatitis B infections among blood donors in Germany 2000-2002: risk of virus transmission and the impact of nucleic acid amplification testing. 
Offergeld, Ruth; Faensen, Daniel; Ritter, Sabine; Hamouda, Osamah
Blood and plasma donations in Germany are collected by several institutions, namely the German Red Cross, community and hospital-based blood services, private blood centres, commercial plasma donation sites and transfusion ...
2011-07-01Zeitschriftenartikel
Der einheitliche Spenderfragebogen 
Offergeld, Ruth; Heiden, Margarethe; Stötzer, Frank; Northoff, Hinnak
Seit Februar 2011 steht ein einheitlicher Blutspenderfragebogen für Blut- und Plasmaspender in Deutschland zur Verfügung. Dieser wurde im Auftrag des Arbeitskreises Blut von einer Expertengruppe entwickelt. Der Fragebogen ...
2011-01-19Zeitschriftenartikel
rapidSTRIPE H1N1 Test for Detection of the Pandemic Swine Origin Influenza A (H1N1) Virus 
Patel, Pranav; Graser, Elmara; Robst, Stephan; Hillert, Roger; Meye, Axel; Hillebrand, Timo; Niedrig, Matthias
The rapidSTRIPE H1N1 test, based on a nucleic acid lateral-flow assay, has been developed for diagnosis of a swine-origin influenza A (H1N1) virus. This test is simple and cost-effective and allows specific detection of ...
2011-04-06Zeitschriftenartikel
Cytomegalovirus e127 protein interacts with the inhibitory CD200 receptor. 
Foster-Cuevas, Mildred; Westerholt, Tina; Ahmed, Mohamed; Brown, Marion H.; Barclay, A. Neil; Voigt, Sebastian
CD200 is a cell surface glycoprotein that binds an inhibitory receptor (CD200R) on myeloid cells. CD200 orthologues are present in many species of virus, and we show that the rat cytomegalovirus CD200 orthologue (e127) is ...
2012-10-01Zeitschriftenartikel
Kurzfristige Prognosen der Krebsmortalität in Deutschland bis 2015 
German short-term cancer mortality predictions up until 2015
Haberland, Jörg; Wolf, Ute; Barnes, Benjamin; Bertz, Joachim; Dahm, Stefan; Laudi, Antje; Kraywinkel, Klaus
Seit vielen Jahren ist die Krebssterblichkeit (Krebsmortalität) insgesamt bei Männern und Frauen in Deutschland erfreulich rückläufig und wird sich dieser Schätzung zufolge auch in den nächsten Jahren so weiterentwickeln. ...
2013-01-08Zeitschriftenartikel
A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant Staphylococcus aureus pandemic 
Holden, Matthew T.G.; Hsu, Li-Yang; Kurt, Kevin; Weinert, Lucy A.; Mather, Alison E.; Harris, Simon R.; Strommenger, Birgit; Layer, Franziska; Witte, Wolfgang; Lencastre, Herminia de; Skov, Robert; Westh, Henrik; Zemličková, Helena; Coombs, Geoffrey; Kearns, Angela M.; Hill, Robert L.R.; Edgeworth, Jonathan; Gould, Ian; Gant, Vanya; Cooke, Jonathan; Edwards, Giles F.; McAdam, Paul R.; Templeton, Kate E.; McCann, Angela; Nübel, Ulrich
The widespread use of antibiotics in association with high-density clinical care has driven the emergence of drug-resistant bacteria that are adapted to thrive in hospitalized patients. Of particular concern are globally ...
2013-02-12Zeitschriftenartikel
Whole Genome Sequencing versus Traditional Genotyping for Investigation of a Mycobacterium tuberculosis Outbreak: A Longitudinal Molecular Epidemiological Study 
Roetzer, Andreas; Diel, Roland; Kohl, Thomas A.; Rückert, Christian; Nübel, Ulrich; Blom, Jochen; Wirth, Thierry; Jaenicke, Sebastian; Schuback, Sieglinde; Rüsch-Gerdes, Sabine; Supply, Philip; Kalinowski, Jörn; Niemann, Stefan
Background: Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to guide efficient tuberculosis control strategies. Traditional strain typing lacks sufficient discriminatory power to resolve large ...
2012-03-22Zeitschriftenartikel
Prevalence and patterns of morbidity among adults in Germany 
Fuchs, Judith; Busch, Markus; Lange, Cornelia; Scheidt-Nave, Christa
Zur Beschreibung von Krankheitsprävalenzen und -mustern bei Erwachsenen in Deutschland wurden Informationen zu 22 chronischen Gesundheitsproblemen bei 21.262 Personen im Alter von 18 bis 100 Jahren (51,5% Frauen) telefonisch ...
2012-03-10Zeitschriftenartikel
The German Environmental Survey for Children (GerES IV): Reference values and distributions for time-location patterns of German children 
Conrad, André; Seiwert, Margarete; Hünken, Andreas; Quarcoo, David; Schlaud, Martin; Groneberg, David
Children's time-location patterns are important determinants of environmental exposure and other health-relevant factors. Building on data of the German Environmental Survey for Children (GerES IV), our study aimed at ...
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