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2015-10-17Zeitschriftenartikel

Methods for Health Economic Evaluation of Vaccines and Immunization Decision Frameworks: A Consensus Framework from a European Vaccine Economics Community

Ultsch, Bernhard; Damm, Oliver; Beutels, Philippe; Bilcke, Joke; Brüggenjürgen, Bernd; Gerber-Grote, Andreas; Greiner, Wolfgang; Hanquet, Germaine; Hutubessy, Raymond; Jit, Mark; Knol, Mirjam; Kries, Rüdiger von; Kuhlmann, Alexander; Levy-Bruhl, Daniel; Perleth, Matthias; Postma, Maarten; Salo, Heini; Siebert, Uwe; Wasem, Jürgen; Wichmann, Ole

Background: Incremental cost-effectiveness and cost-utility analyses [health economic evaluations (HEEs)] of vaccines are routinely considered in decision making on immunization in various industrialized countries. While ...

2015-10-14Zeitschriftenartikel

Extended Microbiological Characterization of Göttingen Minipigs in the Context of Xenotransplantation: Detection and Vertical Transmission of Hepatitis E Virus

Morozov, Vladimir A.; Morozov, Alexey V.; Rotem, Avi; Barkai, Uriel; Bornstein, Stefan; Denner, Joachim

Xenotransplantation has been proposed as a solution to the shortage of suitable human donors. Pigs are currently favoured as donor animals for xenotransplantation of cells, including islet cells, or organs. To reduce the ...

2015-10-17Zeitschriftenartikel

Frequency and impact of confounding by indication and healthy vaccinee bias in observational studies assessing influenza vaccine effectiveness: a systematic review

Remschmidt, Cornelius; Wichmann, Ole; Harder, Thomas

Background: Evidence on influenza vaccine effectiveness (VE) is commonly derived from observational studies. However, these studies are prone to confounding by indication and healthy vaccinee bias. We aimed to systematically ...

2015-10-26Zeitschriftenartikel

Prevalence and temporal trends of physical activity counselling in primary health care in Germany from 1997–1999 to 2008–2011

Gabrys, Lars; Jordan, Susanne; Schlaud, Martin

Background: For patients, usually the first and most preferred contact person on health issues is still the doctor and most persons see their doctor at least once a year. Therefore, physical activity counselling strategies ...

2015-10-16Zeitschriftenartikel

Asylsuchende und Gesundheit in Deutschland: Überblick über epidemiologisch relevante Infektionskrankheiten

Beermann, Sandra; Rexroth, Ute; Kirchner, Markus; Kühne, Anna; Vygen, Sabine; Gilsdorf, Andreas

Das Robert Koch-Institut (RKI) sieht derzeit keine erhöhte Infektionsgefährdung der Allgemeinbevölkerung durch die Asylsuchenden.

2014-10-17Zeitschriftenartikel

Nationale Kohorte – die größte Gesundheitsstudie Deutschlands

Hamouda, Osamah; Krause, Gérard; Pigeot, Iris

2015-10-26Zeitschriftenartikel

Tuberkulose in Deutschland: Ende des rückläufigen Trends?

Robert Koch-Institut

2015-10-26Zeitschriftenartikel

Welt-Poliotag 2015

Noch nie war die globale Situation für die Eradikation so günstig!

Robert Koch-Institut

2015-11-26Zeitschriftenartikel

Qualitative and Quantitative Detection of Botulinum Neurotoxins from Complex Matrices: Results of the First International Proficiency Test

Worbs, Sylvia; Fiebig, Uwe; Zeleny, Reinhard; Schimmel, Heinz; Rummel, Andreas; Luginbühl, Werner; Dorner, Brigitte

In the framework of the EU project EQuATox, a first international proficiency test (PT) on the detection and quantification of botulinum neurotoxins (BoNT) was conducted. Sample materials included BoNT serotypes A, B and ...

2015-11-26Zeitschriftenartikel

Activation of the Mitochondrial Apoptotic Signaling Platform during Rubella Virus Infection

Claus, Claudia; Manssen, Lena; Hübner, Denise; Roßmark, Sarah; Bothe, Viktoria; Petzold, Alice; Große, Claudia; Reins, Mareen; Mankertz, Annette; Frey, Teryl K.; Liebert, Uwe G.

Mitochondria- as well as p53-based signaling pathways are central for the execution of the intrinsic apoptotic cascade. Their contribution to rubella virus (RV)-induced apoptosis was addressed through time-specific evaluation ...

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