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2009-05-14Zeitschriftenartikel
Detection of hepatitis E virus in wild boars of rural and urban regions in Germany and whole genome characterization of an endemic strain 
Schielke, Anika; Sachs, Katja; Lierz, Michael; Appel, Bernd; Jansen, Andreas; Johne, Reimar
Background: Hepatitis E is an increasingly diagnosed human disease in Central Europe. Besides domestic pigs, in which hepatitis E virus (HEV) infection is highly prevalent, wild boars have been identified as a possible ...
2003-05-02Zeitschriftenartikel
Comparison of two DNA targets for the diagnosis of Toxoplasmosis by real-time PCR using fluorescence resonance energy transfer hybridization probes 
Reischl, Udo; Bretagne, Stéphane; Krüger, Dominique; Ernault, Pauline; Costa, Jean-Marc
Background: Toxoplasmosis is an infectious disease caused by the parasitic protozoan Toxoplasma gondii. It is endemic worldwide and, depending on the geographic location, 15 to 85% of the human population are asymptomatically ...
2006-04-10Zeitschriftenartikel
Detection of Norovirus genogroup I and II by multiplex real-time RT- PCR using a 3'-minor groove binder-DNA probe 
Hoehne, Marina; Schreier, Eckart
Background: Due to an increasing number of norovirus infections in the last years rapid, specific, and sensitive diagnostic tools are needed. Reverse transcriptase-polymerase chain reactions (RT-PCR) have become the methods ...
2007-07-03Zeitschriftenartikel
First international diagnostic accuracy study for the serological detection of West Nile virus infection 
Niedrig, Matthias; Mantke, Oliver Donoso; Altmann, Doris; Zeller, Hervé
Background: The diagnosis of an acute or convalescent West Nile (WN) virus infection can be confirmed by various serological assays such as enzyme immunoassay (EIA), immunofluorescence assay (IFA), or neutralisation test ...
2009-11-12Zeitschriftenartikel
Clostridium difficile ribotypes 001, 017, and 027 are associated with lethal C. difficile infection in Hesse, Germany 
Arvand, M.; Hauri, Anja M.; Zaiß, Henning; Witte, Wolfgang; Bettge-Weller, G.
From January 2008 to April 2009, 72 cases of severe Clostridium difficile infection were reported from 18 different districts in the state of Hesse, Germany. A total of 41 C. difficile isolates from 41 patients were subjected ...
2007-11-15Zeitschriftenartikel
A case of Clostridium difficile-associated disease due to the highly virulent clone of Clostridium difficile PCR ribotype 027, March 2007 in Germany 
Zaiß, Henning; Weile, J.; Ackermann, G.; Kuijper, Ed J.; Witte, Wolfgang; Nübel, Ulrich
2009-02-26Zeitschriftenartikel
Capability of the viral NS1 proteins to bind to the cellular adaptor proteins Crk and CrkL determines sensitivity of influenza viruses to Crk/CrkL expression 
Hrincius, Eike R.; Wolff, Thorsten; Ludwig, Stephan; Ehrhardt, Christina
2009-02-12Zeitschriftenartikel
Wie groß sind die Differenzen zwischen den europäischen Pandemieplänen, sind sie relevant und woher stammen sie? 
Differences in European influenza pandemic preparedness plans, how important are they and what are the underlying reasons?
Haas, Walter; Straetemans, Masja; Pfaff, Günter; Nicoll, A.
Die Koordination der Influenzapandemieplanung innerhalb Europas ist für Deutschland von besonderer Bedeutung, da 10 von 16 Bundesländern an Nachbarstaaten angrenzen. Hierbei müssen nicht nur sprachliche Barrieren überwunden ...
2007-04-05Zeitschriftenartikel
Verlauf der HIV-Epidemie in Deutschland 
Epidemiology of HIV infections in Germany
Hamouda, Osamah; Marcus, Ulrich; Voß, Lieselotte; Kollan, Christian
Zwischen dem Zeitpunkt der Infektion und dem Zeitpunkt der Diagnose der HIV-Infektion vergeht in aller Regel ein individuell unterschiedlich langer Zeitraum von oftmals mehreren Jahren. Die Meldedaten über HIV-Neudiagnosen ...
2010-01-15Zeitschriftenartikel
Human Coronavirus NL63 Open Reading Frame 3 encodes a virion-incorporated N-glycosylated membrane protein 
Müller, Marcel A.; Hoek, Lia van der; Voss, Daniel; Bader, Oliver; Lehmann, Dörte; Schulz, Axel R.; Kallies, Stephan; Suliman, Tasnim; Fielding, Burtram C; Drosten, Christian; Niedrig, Matthias
Background: Human pathogenic coronavirus NL63 (hCoV-NL63) is a group 1 (alpha) coronavirus commonly associated with respiratory tract infections. In addition to known non-structural and structural proteins all coronaviruses ...
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