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Now showing items 2531-2540 of 11373

2012-05-23Zeitschriftenartikel

Chromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications

Meyer, Stefan; Neitzel, Heidemarie; Tönnies, Holger

Fanconi anaemia (FA) is an inherited disease with congenital and developmental abnormalities, bone marrow failure, and extreme risk of leukemic transformation. Bone marrow surveillance is an important part of the clinical ...

2011-06-21Zeitschriftenartikel

Molecular characterization of blaNDM-1 in an Acinetobacter baumannii strain isolated in Germany in 2007

Pfeifer, Yvonne; Wilharm, Gottfried; Zander, Esther; Wichelhaus, Thomas A.; Göttig, Stefan; Hunfeld, Klaus-Peter; Seifert, Harald; Witte, Wolfgang; Higgins, Paul G.

Objectives: To investigate the genetic environment of the metallo-β-lactamase gene blaNDM-1 in an Acinetobacter baumannii isolated in 2007 in a German hospital. Methods: Antimicrobial susceptibility testing was performed ...

2011-05-30Zeitschriftenartikel

Application of a split luciferase complementation assay for the detection of viral protein–protein interactions

Deng, Qiji; Wang, Dan; Xiang, Xiaoxiao; Gao, Xiaofei; Hardwidge, Philip R.; Kaushik, Radhey S.; Wolff, Thorsten; Chakravarty, Suvobrata; Li, Feng

Intraviral protein-protein interactions are critical for virus survival in the host. Discovery of such interactions is important to understand molecular mechanisms of viral replication and pathogenesis. The development of ...

2011-05-25Zeitschriftenartikel

Population-wide use of behavioural prevention and counselling programmes for lifestyle-related cardiovascular risk factors in Germany

Schmitz, Roma; Jordan, Susanne; Müters, Stephan; Neuhauser, Hannelore

Background: Behavioural prevention and counselling programmes for lifestyle-related cardiovascular risk factors are widely offered. However, their population-wide use is largely unexplored, particularly in high-risk persons ...

2012-09-01Zeitschriftenartikel

Henipavirus-related Sequences in Fruit Bat Bushmeat, Republic of Congo

Weiss, Sabrina; Nowak, Kathrin; Fahr, Jakob; Wibbelt, Gudrun; Mombouli, Jean-Vivien; Parra, Henri- Joseph; Wolfe, Nathan D.; Schneider, Bradley S.; Leendertz, Fabian

TO THE EDITOR: Bats are hosts for various emerging viruses, including the zoonotic paramyxoviruses Hendra virus and Nipah virus, which occur in Australia and Southeast Asia, respectively, and cause severe disease outbreaks ...

2012-06-19Zeitschriftenartikel

Hautkrebs – Epidemiologie und Früherkennung

Kraywinkel, Klaus; Wolf, Ute; Katalinic, Alexander

2012-04-19Zeitschriftenartikel

Real-time cytotoxicity assay for rapid and sensitive detection of ricin from complex matrices.

Pauly, Diana; Worbs, Sylvia; Kirchner, Sebastian; Shatohina, Olena; Dorner, Martin; Dorner, Brigitte

Background: In the context of a potential bioterrorist attack sensitive and fast detection of functionally active toxins such as ricin from complex matrices is necessary to be able to start timely countermeasures. One of ...

2012-03-27Zeitschriftenartikel

Lessons from a one-year hospital-based surveillance of acute respiratory infections in Berlin- comparing case definitions to monitor influenza

Nachtnebel, Matthias; Greutélaers, Benedikt; Falkenhorst, Gerhard; Jorgensen, Pernille; Dehnert, Manuel; Schweiger, Brunhilde; Träder, Christian; Buda, Silke; Eckmanns, Tim; Wichmann, Ole; Hellenbrand, Wiebke

Background: Surveillance of severe acute respiratory infections (SARI) in sentinel hospitals is recommended to estimate the burden of severe influenza-cases. Therefore, we monitored patients admitted with respiratory ...

2012-03-09Zeitschriftenartikel

Phylogenetic reconstruction of dengue virus type 2 in Colombia

Méndez, Jairo A.; Usme-Ciro, José A.; Domingo, Cristina; Rey, Gloria J.; Sánchez, Juan A.; Tenorio, Antonio; Gallego-Gomez, Juan C.

Background: Dengue fever is perhaps the most important viral re-emergent disease especially in tropical and subtropical countries, affecting about 50 million people around the world yearly. In Colombia, dengue virus was ...

2011-04-28Zeitschriftenartikel

Generation and characterisation of monoclonal antibodies against influenza virus A, subtype H5N1

Linke, Sonja; Neubauer, Katrin; Dorner, Martin; Dorner, Brigitte; Pauli, Georg; Schweiger, Brunhilde

The emergence of highly pathogenic avian influenza A virus (HPAIV) subtype H5N1 in 1997 has since resulted in large outbreaks in poultry and in transmission from poultry to humans, mostly in southeast Asia, but also in ...

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