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2018-01-26Zeitschriftenartikel

High dietary zinc feeding promotes persistence of multi-resistant E. coli in the swine gut

Ciesinski, Lisa; Guenther, Sebastian; Pieper, Robert; Kalisch, Martin; Bednorz, Carmen; Wieler, Lothar H.

High levels of zinc oxide are used frequently as feed additive in pigs to improve gut health and growth performance and are still suggested as an alternative to antimicrobial growth promoters. However, we have recently ...

2018-02-01Zeitschriftenartikel

Hervey virus: Study on co-circulation with Henipaviruses in Pteropid bats within their distribution range from Australia to Africa

Kohl, Claudia; Tachedjian, Mary; Todd, Shawn; Monaghan, Paul; Boyd, Victoria; Marsh, Glenn A.; Crameri, Gary; Field, Hume; Kurth, Andreas; Smith, Ina; Wang, Lin-Fa

In 2011, an unusually large number of independent Hendra virus outbreaks were recorded on horse properties in Queensland and New South Wales, Australia. Urine from bat colonies adjacent to the outbreak sites were sampled ...

2017-11-08Zeitschriftenartikel

Epidemiologie des CUP-Syndroms in Deutschland

Kraywinkel, Klaus; Zeissig, Sylke Ruth

Der Artikel gibt einen Überblick über Inzidenz‑, Mortalitäts- und Überlebensraten des „cancer of unknown primary“ (CUP) in Deutschland, beruhend auf den Daten der epidemiologischen Krebsregister in Deutschland sowie der ...

2016-05-13Zeitschriftenartikel

Bacterial contamination of water samples in Gabon, 2013

Ehrhardt, Jonas; Alabi, Abraham S.; Kremsner, Peter G.; Rabsch, Wolfgang; Becker, Karsten; Foguim, Francis Tsombeng; Kuczius, Thorsten; Esen, Meral; Schaumburg, Frieder

Contamination of water is a major burden in the public health setting of developing countries. We therefore assessed the quality of water samples in Gabon in 2013. The main findings were a contamination rate with coliforms ...

2018-01-11Zeitschriftenartikel

Whole-Genome Draft Sequences of Nine Asymptomatic Escherichia coli Bacteriuria Isolates from Diabetic Patients

Stork, Christoph; Kovács, Beáta; Trost, Eva; Kovács, Tamás; Schneider, György; Rózsai, Barnabás; Kerényi, Monika; Emődy, Levente; Dobrindt, Ulrich

Escherichia coli can colonize the urinary bladder without causing a disease response in the host. This asymptomatic bacteriuria (ABU) can protect against recurrent symptomatic urinary tract infection by virulent bacteria. ...

2018-02-20Zeitschriftenartikel

Strain-dependent effects of clinical echovirus 30 outbreak isolates at the blood-CSF barrier

Dahm, Tobias; Adams, Ortwin; Boettcher, Sindy; Diedrich, Sabine; Morozov, Vasily; Hansman, Grant; Fallier-Becker, Petra; Schädler, Sebastian; Burkhardt, Claus J.; Weiss, Christel; Stump-Guthier, Carolin; Ishikawa, Hiroshi; Schroten, Horst; Schwerk, Christian; Tenenbaum, Tobias; Rudolph, Henriette

Background: Echovirus (E) 30 (E-30) meningitis is characterized by neuroinflammation involving immune cell pleocytosis at the protective barriers of the central nervous system (CNS). In this context, infection of the ...

2018-02-23Zeitschriftenartikel

Whole Genome Sequence Analysis of CTX-M-15 Producing Klebsiella Isolates Allowed Dissecting a Polyclonal Outbreak Scenario

Becker, Laura; Fuchs, Stephan; Pfeifer, Yvonne; Semmler, Torsten; Eckmanns, Tim; Korr, Gerit; Sissolak, Dagmar; Friedrichs, Michael; Zill, Edith; Tung, Mei-Lin; Dohle, Christian; Kaase, Martin; Gatermann, Sören; Rüssmann, Holger; Steglich, Matthias; Haller, Sebastian; Werner, Guido

Extended-spectrum β-lactamase (ESBL) producing Klebsiella pneumoniae pose an important threat of infection with increased morbidity and mortality, especially for immunocompromised patients. Here, we use the rise of ...

2018-02-16Zeitschriftenartikel

Tularemia in Germany—A Re-emerging Zoonosis

Faber, Mirko; Heuner, Klaus; Jacob, Daniela; Grunow, Roland

Tularemia, also known as “rabbit fever,” is a zoonosis caused by the facultative intracellular, gram-negative bacterium Francisella tularensis. Infection occurs through contact with infected animals (often hares), arthropod ...

2018-02-12Zeitschriftenartikel

Recombinant IFN-γ from the bank vole Myodes glareolus: a novel tool for research on rodent reservoirs of zoonotic pathogens

Torelli, Francesca; Zander, Steffen; Ellerbrok, Heinz; Kochs, Georg; Ulrich, Rainer G.; Klotz, Christian; Seeber, Frank

Rodent species like Myodes glareolus and Microtus spp. are natural reservoirs for many zoonotic pathogens causing human diseases and are gaining increasing interest in the field of eco-immunology as candidate animal models. ...

2018-02-13Zeitschriftenartikel

HERVs New Role in Cancer: From Accused Perpetrators to Cheerful Protectors

Bannert, Norbert; Hofmann, Henning; Block, Adriana; Hohn, Oliver

Initial indications that retroviruses are connected to neoplastic transformation were seen more than a century ago. This concept has also been tested for endogenized retroviruses (ERVs) that are abundantly expressed in ...

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