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2015-07-28Zeitschriftenartikel

The PadR-like transcriptional regulator LftR ensures efficient invasion of Listeria monocytogenes into human host cells

Kaval, Karan G.; Hahn, Birgitt; Tusamda, Nayana; Albrecht, Dirk; Halbedel, Sven

Invasion of the bacterial pathogen Listeria monocytogenes into human host cells requires specialized surface molecules for attachment and induction of phagocytosis. However, efficient invasion is also dependent on factors ...

2014-03-21Zeitschriftenartikel

The type IV secretion protein TraK from the Enterococcus conjugative plasmid pIP501 exhibits a novel fold

Goessweiner-Mohr, Nikolaus; Fercher, Christian; Arends, Karsten; Gruenberger, Ruth Birner-; Gomez, Diana Laverde-; Huebner, Johannes; Grohmann, Elisabeth; Keller, Walter

Conjugative plasmid transfer presents a serious threat to human health as the most important means of spreading antibiotic resistance and virulence genes among bacteria. The required direct cell-cell contact is established ...

2014-05-10Zeitschriftenartikel

Recommendations for Promoting Physical Activity for Children and Adolescents in Germany. A Consensus Statement

Graf, Christine; Beneke, Ralph; Bloch, Wilhelm; Bucksch, Jens; Dordel, Sigrid; Eiser, Stefanie; Ferrari, Nina; Koch, Benjamin; Krug, Susanne; Lawrenz, Wolfgang; Manz, Kristin; Naul, Roland; Oberhoffer, Renate; Quilling, Eike; Schulz, Henry; Stemper, Theo; Stibbe, Günter; Tokarski, Walter; Völker, Klaus; Woll, Alexander

Increasing physical activity and reduction of sedentary behaviour play important roles in health promotion and prevention of lifestyle-related diseases in children and adolescents. However, the question of how much physical ...

2014-12-13Zeitschriftenartikel

Accidental exposure to gas emissions from transit goods treated for pest control

Kloth, Stefan; Baur, Xaver; Göen, Thomas; Budnik, Lygia Therese

Background: International phytosanitary standards ISPM 15 require (since 2007) fumigation or heat treatment for shipping and storage. Those dealing with fumigated freight might be accidentally exposed. In this paper we ...

2015-08-13Zeitschriftenartikel

Age-related prevalence of cross-reactive antibodies against influenza A(H3N2) variant virus, Germany, 2003 to 2010

Blümel, Benjamin; Schweiger, Brunhilde; Dehnert, Manuel; Buda, Silke; Reuss, Annicka; Czogiel, Irina; Kamtsiuris, Panagiotis; Schlaud, Martin; Poethko-Müller, Christina; Thamm, Michael; Haas, Walter

To estimate susceptibility to the swine-origin influenza A(H3N2) variant virus (A(H3N2)v) in the German population, we investigated cross-reactive antibodies against this virus and factors associated with seroprotective ...

2014-12-05Zeitschriftenartikel

Self-assembly of a cholesteryl-modified nucleoside into tubular structures from giant unilamellar vesicles

Losensky, Luisa; Chiantia, Salvatore; Holland, Gudrun; Laue, Michael; Petran, Anca; Liebscher, Jürgen; Arbuzova, Anna

We recently reported the formation of micro- and nanometer thick tubules in a binary system of cholesteryl-modified aminouridine and a phosphatidylcholine in aqueous solution upon cooling from 70 °C to room temperature ...

2015-01-29Zeitschriftenartikel

Development and Validation of Correction Formulas for Self-Reported Height and Weight to Estimate BMI in Adolescents. Results from the KiGGS Study

Brettschneider, Anna-Kristin; Rosario, Angelika Schaffrath; Wiegand, Susanna; Kollock, M.; Ellert, Ute

Objective: The use of reported instead of measured height and weight induces a bias in prevalence rates for overweight and obesity. Therefore, correction formulas are necessary. Methods: Self-reported and measured height ...

2014-09-05Zeitschriftenartikel

Rapid and simultaneous detection of ricin, staphylococcal enterotoxin B and saxitoxin by chemiluminescence-based microarray immunoassay

Szkola, A.; Linares, E. M.; Worbs, Sylvia; Dorner, Brigitte; Dietrich, R.; Märtlbauer, E.; Niessner, R.; Seidel, Michael

Simultaneous detection of small and large molecules on microarray immunoassays is a challenge that limits some applications in multiplex analysis. This is the case for biosecurity, where fast, cheap and reliable simultaneous ...

2015-12-08Zeitschriftenartikel

Two Cytoplasmic Acylation Sites and an Adjacent Hydrophobic Residue, but No Other Conserved Amino Acids in the Cytoplasmic Tail of HA from Influenza A Virus Are Crucial for Virus Replication

Siche, Stefanie; Brett, Katharina; Möller, Lars; Kordyukova, Larisa V.; Mintaev, Ramil R.; Alexeevski, Andrei V.; Veit, Michael

Recruitment of the matrix protein M1 to the assembly site of the influenza virus is thought to be mediated by interactions with the cytoplasmic tail of hemagglutinin (HA). Based on a comprehensive sequence comparison of ...

2012-12-28Zeitschriftenartikel

Epidemiology and cost of herpes zoster and postherpetic neuralgia in Germany

Ultsch, Bernhard; Köster, Ingrid; Reinhold, Thomas; Siedler, Anette; Krause, Gérard; Icks, Andrea; Schubert, Ingrid; Wichmann, Ole

After acquiring a varicella virus infection, the virus can reactivate and cause herpes zoster (HZ)—a painful skin rash. A complication of HZ is long-term persistence of pain after the rash has resolved (so-called postherpetic ...

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