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2017-11-24Zeitschriftenartikel

AureoWiki ̵ The repository of the Staphylococcus aureus research and annotation community

Fuchs, Stephan; Mehlan, Henry; Bernhardt, Jörg; Hennig, André; Michalik, Stephan; Surmann, Kristin; Pané-Farré, Jan; Giese, Anne; Weiss, Stefan; Backert, Linus; Herbig, Alexander; Nieselt, Kay; Hecker, Michael; Völker, Uwe; Mäder, Ulrike

In light of continuously accumulating data and knowledge on major human pathogens, comprehensive and up-to-date sources of easily accessible information are urgently required. The AureoWiki database (http://aureowiki.med ...

2018-05-02Zeitschriftenartikel

Genome-based analysis of Carbapenemase-producing Klebsiella pneumoniae isolates from German hospital patients, 2008-2014

Becker, Laura; Kaase, Martin; Pfeifer, Yvonne; Fuchs, Stephan; Reuss, Annicka; von Laer, Anja; Abu Sin, Muna; Korte-Berwanger, Miriam; Gatermann, Sören; Werner, Guido

Background By using whole genome sequence data we aimed at describing a population snapshot of carbapenemase-producing K. pneumoniae isolated from hospitalized patients in Germany between 2008 and 2014. Methods We ...

2018-07-12Zeitschriftenartikel

Absence of IL-10 production by human PBMCs co-cultivated with human cells expressing or secreting retroviral immunosuppressive domains

Ivanusic, Daniel; Pietsch, Heiko; König, Jasper; Denner, Joachim

Immunosuppression by retroviruses including the human immunodeficiency virus—1 (HIV-1) is well known, however the mechanisms how retroviruses induce this immunosuppression is not fully investigated. It was shown that ...

2018-06-05Zeitschriftenartikel

Carbapenem non-susceptibility of Klebsiella pneumoniae isolates in hospitals from 2011 to 2016, data from the German Antimicrobial Resistance Surveillance (ARS)

Koppe, Uwe; von Laer, Anja; Kroll, Lars E.; Noll, Ines; Feig, Marcel; Schneider, Marc; Claus, Hermann; Eckmanns, Tim; Abu Sin, Muna

Background: Carbapenem resistance in Klebsiella pneumoniae is of significant public health concern and recently spread across several countries. We investigated the extent of carbapenem non-susceptibility in K. pneumoniae ...

2018-05-15Zeitschriftenartikel

Immunity levels to poliovirus in Lao children and adults before the vaccine-derived poliovirus outbreak: A retrospective study

Pauly, Maude; Black, Antony P.; Khampanisong, Phonepaseuth; Nouanthong, Phonethipsavanh; Hübschen, Judith M.; Nanthavong, Naphavanh; Sayasinh, Kong; Jutavijittum, Prapan; Samountry, Bounthome; Xeuatvongsa, Anonh; Diedrich, Sabine; Muller, Claude P.

In 2015, several provinces in Lao People's Democratic Republic (Lao PDR) experienced a vaccine-derived poliovirus outbreak. This survey was conducted (i) to evaluate the vaccination coverage in different settings and cohorts ...

2018-02-24Zeitschriftenartikel

The use of high-throughput sequencing to investigate an outbreak of glycopeptide-resistant Enterococcus faecium with a novel quinupristin-dalfopristin resistance mechanism

Shaw, Timothy D.; Fairley, D. J.; Schneiders, T.; Pathiraja, M.; Hill, R. L. R.; Werner, Guido; Elborn, J. S.; McMullan, R.

High-throughput sequencing (HTS) has successfully identified novel resistance genes in enterococci and determined clonal relatedness in outbreak analysis. We report the use of HTS to investigate two concurrent outbreaks ...

2018-05-23Zeitschriftenartikel

HDV infection rates in northern Vietnam

Binh, Mai Thanh; Hoan, Nghiem Xuan; Tong, Hoang Van; Giang, Dao Phuong; Sy, Bui Tien; Toan, Nguyen Linh; Song, Le Huu; Bang, Mai Hong; Wedemeyer, Heiner; Meyer, Christian G.; Kremsner, Peter G.; Bock, Thomas; Velavan, Thirumalaisamy P.

Hepatitis D caused by the hepatitis delta virus (HDV) is a serious health problem in many regions of the world. A total of 546 HBV-infected patients were enrolled from 2013 to 2015 and classified clinically into the subgroups ...

2018-01-24Zeitschriftenartikel

Comparative analysis of Salivette® and paraffin gum preparations for establishment of a metaproteomics analysis pipeline for stimulated human saliva

Rabe, Alexander; Salazar, Manuela Gesell; Fuchs, Stephan; Kocher, Thomas; Völker, Uwe

The value of saliva as a diagnostic tool can be increased by taxonomic and functional analyses of the microbiota as recently demonstrated. In this proof-of-principle study, we compare two collection methods (Salivette® ...

2018-05-10Zeitschriftenartikel

Draft Genome Sequences of Plant-Associated Bacillus Strains Isolated from the Qinghai-Tibetan Plateau

Wu, Huijun; Borriss, Rainer; Xue, Pengqi; Liu, Fang; Qiao, Junqing; Schneider, Andy; Lasch, Peter; Gao, Xuewen

Here, we report the draft genome sequences of 45 plant-associated Bacillus strains isolated from the Qinghai-Tibetan plateau. According to their genome sequences, 28 isolates were assigned to 10 Bacillus species. Seventeen ...

2018-09-12Berichte und sonstige Texte

Nach der schweren Grippewelle und vor der nächsten Grippewelle: Schutzmöglichkeiten besser nutzen!

Robert Koch-Institut

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