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Now showing items 5191-5200 of 11373

2018-07-16Zeitschriftenartikel

Increasing influenza and pneumococcal vaccine uptake in the elderly: study protocol for the multi-methods prospective intervention study Vaccination60+

Betsch, Cornelia; Rossmann, Constanze; Pletz, Mathias W.; Vollmar, Horst C.; Freytag, Antje; Wichmann, Ole; Hanke, Regina; Hanke, Wolfgang; Heinemeier, Dorothee; Schmid, Philipp; Eitze, Sarah; Weber, Winja; Reinhardt, Anne; Küpke, Nora K.; Forstner, Christina; Fleischmann-Struzek, Carolin; Mikolajetz, Anna; Römhild, Josephine; Neufeind, Julia; Rieck, Thorsten; Suchecka, Kasia; Reinhart, Konrad

Background: Influenza and pneumococcal vaccination can prevent disease and potentially life-threatening complications like sepsis. Elderly people have an increased risk of severe disease and therefore constitute a major ...

2018-05-18Zeitschriftenartikel

Easy and accurate reconstruction of whole HIV genomes from short-read sequence data with shiver

Wymant, Chris; Blanquart, François; Golubchik, Tanya; Gall, Astrid; Bakker, Margreet; Bezemer, Daniela; Croucher, Nicholas J.; Hall, Matthew; Hillebregt, Mariska; Ong, Swee Hoe; Ratmann, Oliver; Albert, Jan; Bannert, Norbert; Fellay, Jacques; Fransen, Katrien; Gourlay, Annabelle; Grabowski, M. Kate; Gunsenheimer-Bartmeyer, Barbara; Günthard, Huldrych F.; Kivelä, Pia; Kouyos, Roger; Laeyendecker, Oliver; Liitsola, Kirsi; Meyer, Laurence; Porter, Kholoud; Ristola, Matti; van Sighem, Ard; Berkhout, Ben; Cornelissen, Marion; Kellam, Paul; Reiss, Peter; Fraser, Christophe

Studying the evolution of viruses and their molecular epidemiology relies on accurate viral sequence data, so that small differences between similar viruses can be meaningfully interpreted. Despite its higher throughput ...

2018-06-14Zeitschriftenartikel

Multispecies and Clonal Dissemination of OXA-48 Carbapenemase in Enterobacteriaceae From Companion Animals in Germany, 2009—2016

Pulss, Sandra; Stolle, Inka; Stamm, Ivonne; Leidner, Ursula; Heydel, Carsten; Semmler, Torsten; Prenger-Berninghoff, Ellen; Ewers, Christa

The increasing spread of carbapenemase-producing Enterobacteriaceae (CPE) poses a serious threat to public health. Recent studies suggested animals as a putative source of such bacteria. We investigated 19,025 Escherichia ...

2018-06-12Zeitschriftenartikel

High genomic diversity of multi-drug resistant wastewater Escherichia coli

Mahfouz, Norhan; Caucci, Serena; Achatz, Eric; Semmler, Torsten; Guenther, Sebastian; Berendonk, Thomas U.; Schroeder, Michael

Wastewater treatment plants play an important role in the emergence of antibiotic resistance. They provide a hot spot for exchange of resistance within and between species. Here, we analyse and quantify the genomic diversity ...

2018-06-22Zeitschriftenartikel

The Expression of Uncoupling Protein 3 Coincides With the Fatty Acid Oxidation Type of Metabolism in Adult Murine Heart

Hilse, Karolina E.; Rupprecht, Anne; Egerbacher, Monika; Bardakji, Sarah; Zimmermann, Lars; Seiler Wulczyn, Andrea E. M.; Pohl, Elena E.

The involvement of mitochondrial uncoupling proteins 2 and 3 in the pathogenesis of cardiovascular diseases is widely acknowledged. However, contradictory reports show that the functions of UCP2/UCP3 are still disputed. ...

2018-05-02Zeitschriftenartikel

Integration von Sekundärdaten in die Nationale Diabetes-Surveillance

Hintergrund, Ziele und Ergebnisse des Sekundärdaten-Workshops am Robert Koch-Institut

Schmidt, Christian; Bätzing-Feigenbaum, Jörg; Bestmann, Anja; Brinks, Ralph; Dreß, Jochen; Goffrier, Benjamin; Hagen, Bernd; Laux, Gunter; Pollmanns, Johannes; Schröder, Helmut; Stahl, Teresa; Baumert, Jens; Du, Yong; Gabrys, Lars; Heidemann, Christin; Paprott, Rebecca; Scheidt-Nave, Christa; Teti, Andrea; Ziese, Thomas

Epidemiologische Daten belegen, dass Diabetes mellitus in Deutschland wie in vielen anderen Ländern eine hohe Public-health-Relevanz hat. Am Robert Koch-Institut (RKI) wird derzeit eine Nationale Diabetes-Surveillance ...

2018-06-15Zeitschriftenartikel

ESBL-plasmid carriage in E. coli enhances in vitro bacterial competition fitness and serum resistance in some strains of pandemic sequence types without overall fitness cost

Ranjan, Amit; Scholz, Julia; Semmler, Torsten; Wieler, Lothar H.; Ewers, Christa; Müller, Stefanie; Pickard, Derek J.; Schierack, Peter; Tedin, Karsten; Ahmed, Niyaz; Schaufler, Katharina; Guenther, Sebastian

Background: Extended spectrum beta lactamase (ESBL)-producing extraintestinal pathogenic Escherichia coli infections are of global interest because of their clinical and economic impact. The ESBL resistance genes disseminate ...

2018-06-14Zeitschriftenartikel

Smear Microscopy for Diagnosis of Pulmonary Tuberculosis in Eastern Sudan

Shuaib, Yassir A.; Khalil, Eltahir A. G.; Schaible, Ulrich E.; Wieler, Lothar H.; Bakheit, Mohammed A. M.; Mohamed-Noor, Saad E.; Abdalla, Mohamed A.; Homolka, Susanne; Andres, Sönke; Hillemann, Doris; Lonnroth, Knut; Richter, Elvira; Niemann, Stefan; Kranzer, Katharina

Background. In Sudan, tuberculosis diagnosis largely relies on clinical symptoms and smear microscopy as in many other low- and middle-income countries. The aim of this study was to investigate the positive predictive value ...

2018-08-24Zeitschriftenartikel

Evaluation of the statutory surveillance system for invasive MRSA infections in Germany, 2016–2017

Schönfeld, Viktoria; Diercke, Michaela; Gilsdorf, Andreas; Eckmanns, Tim; Walter, Jan

Background: Mandatory notification of invasive methicillin-resistant Staphylococcus aureus (MRSA) infections was introduced for laboratories in Germany in 2009. The aims were to support local health authorities (LHAs) in ...

2018-06-27Zeitschriftenartikel

Human coronavirus OC43 outbreak in wild chimpanzees, Côte d´Ivoire, 2016

Patrono, Livia V.; Samuni, Liran; Corman, Victor M.; Nourifar, Leila; Röthemeier, Caroline; Wittig, Roman M.; Drosten, Christian; Calvignac-Spencer, Sébastien; Leendertz, Fabian H.

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