2018-06-26Zeitschriftenartikel
Replacing the mouse bioassay for diagnostics and potency testing of botulinum neurotoxins – progress and challenges
Stern, Daniel; von Berg, Laura; Skiba, Martin; Dorner, Martin B.; Dorner, Brigitte G.
Botulinum neurotoxins (BoNTs) are the most potent toxins known and the
causative agents of the rare but potentially life-threatening disease botulism. The
elaborate mode of action of BoNTs at the molecular level, their ...