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2019-11-27Zeitschriftenartikel

Influenza-Wochenbericht

Kalenderwoche 47/2019 (16.11. bis 22.11.2019)

Robert Koch-Institut

Die Aktivität der akuten Atemwegserkrankungen (ARE) ist in der 47. Kalenderwoche (KW) 2019 bundesweit stabil geblieben. Die Werte des Praxisindex lagen in der 47. KW insgesamt im Bereich der ARE-Hintergrund-Aktivität. Im ...

2019-08-16Zeitschriftenartikel

A Robust and Universal Metaproteomics Workflow for Research Studies and Routine Diagnostics Within 24 h Using Phenol Extraction, FASP Digest, and the MetaProteomeAnalyzer

Heyer, Robert; Schallert, Kay; Büdel, Anja; Zoun, Roman; Dorl, Sebastian; Behne, Alexander; Kohrs, Fabian; Püttker, Sebastian; Siewert, Corina; Muth, Thilo; Saake, Gunter; Reichl, Udo; Benndorf, Dirk

The investigation of microbial proteins by mass spectrometry (metaproteomics) is a key technology for simultaneously assessing the taxonomic composition and the functionality of microbial communities in medical, environmental, ...

2019-09-14Zeitschriftenartikel

Puumala and Tula Virus Differ in Replication Kinetics and Innate Immune Stimulation in Human Endothelial Cells and Macrophages

Bourquain, Daniel; Bodenstein, Clemens; Schürer, Stefanie; Schaade, Lars

Old world hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) upon zoonotic transmission to humans. In Europe, the Puumala virus (PUUV) is the main causative agent of HFRS. Tula virus (TULV) is also widely ...

2019-07-09Zeitschriftenartikel

Recursive feature elimination in random forest classification supports nanomaterial grouping

Bahl, Aileen; Hellack, Bryan; Balas, Mihaela; Dinischiotu, Anca; Wiemann, Martin; Brinkmann, Joep; Luch, Andreas; Renard, Bernhard Y.; Haase, Andrea

Nanomaterials (NMs) can be produced in numerous different variants of the same chemical substance. An in-depth safety assessment for each variant by generating test data will simply not be feasible. Thus, NM grouping ...

2019-09-26Zeitschriftenartikel

Osmolyte homeostasis controls single-cell growth rate and maximum cell size of Saccharomyces cerevisiae

Altenburg, Tom; Goldenbogen, Björn; Uhlendorf, Jannis; Klipp, Edda

Cell growth is well described at the population level, but precisely how nutrient and water uptake and cell wall expansion drive the growth of single cells is poorly understood. Supported by measurements of single-cell ...

2019-09-09Zeitschriftenartikel

Time trends in healthy lifestyle among adults in Germany: Results from three national health interview and examination surveys between 1990 and 2011

Finger, Jonas D.; Busch, Markus A.; Heidemann, Christin; Lange, Cornelia; Mensink, Gert B. M.; Schienkiewitz, Anja

Background The combined impact of multiple healthy behaviors on health exceeds that of single behaviors. This study aimed to estimate trends in the prevalence of a healthy lifestyle among adults in Germany. Methods A ...

2019-09-05Zeitschriftenartikel

Salmonellosis outbreak with novel Salmonella enterica subspecies enterica serotype (11:z41:e,n,z15) attributable to sesame products in five European countries, 2016 to 2017

Meinen, Anika; Simon, Sandra; Banerji, Sangeeta; Szabo, Istvan; Malorny, Burkhard; Borowiak, Maria; Hadziabdic, Sead; Becker, Natalie; Luber, Petra; Lohr, Dorothee; Harms, Carolin; Plenge-Bönig, Anita; Mellou, Kassiani; Mandilara, Georgia; Mossong, Joël; Ragimbeau, Catherine; Weicherding, Pierre; Hau, Patrick; Dědičová, Daniela; Šafaříková, Lucie; Nair, Satheesh; Dallman, Timothy J.; Larkin, Lesley; McCormick, Jacquelyn; De Pinna, Elizabeth; Severi, Ettore; Kotila, Saara; Niskanen, Taina; Rizzi, Valentina; Deserio, Domenico; Flieger, Antje; Stark, Klaus

In spring 2016, Greece reported an outbreak caused by a previously undescribed Salmonellaenterica subsp. enterica serotype (antigenic formula 11:z41:e,n,z15) via the Epidemic Intelligence Information System for Food- and ...

2019-10-03Zeitschriftenartikel

Factors associated with the informal use of HIV pre‐exposure prophylaxis in Germany: a cross‐sectional study

Koppe, Uwe; Marcus, Ulrich; Albrecht, Stefan; Jansen, Klaus; Jessen, Heiko; Gunsenheimer-Bartmeyer, Barbara; Bremer, Viviane

Introduction Until September 2019, pre‐exposure prophylaxis (PrEP) with tenofovir disoproxil/emtricitabine for HIV prevention was not covered by health insurance plans in Germany, and was only available through private ...

2019-09-26Zeitschriftenartikel

Increased detection of enterovirus A71 infections, Germany, 2019

Böttcher, Sindy; Diedrich, Sabine; Keeren, Kathrin; the Laboratory Network for Enterovirus Diagnotic (LaNED)

We report on the increased circulation of enterovirus A71 in Germany in 2019. Strains were mainly identified in hospitalised patients with suspected aseptic meningitis/encephalitis. Molecular analysis showed co-circulation ...

2019-09-27Zeitschriftenartikel

Ständige Impfkommission (STIKO): Die wichtigsten Änderungen im Überblick

Koch, Judith; Vygen-Bonnet, Sabine; Wichmann, Ole

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