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2019-12-13Zeitschriftenartikel

Bornavirus-Infektionen: Hohe Letalität durch fulminante Meningoenzephalitiden

Pörtner, Kirsten; Frank, Christina; Schmidt-Chanasit, Jonas; Beer, Martin; Rubbenstroth, Dennis; Tappe, Dennis

2020-02-16Zeitschriftenartikel

Molecular Characterization and Clinical Description of Non-Polio Enteroviruses Detected in Stool Samples from HIV-Positive and HIV-Negative Adults in Ghana

Di Christanziano, Veronica; Weimer, Kristina; Böttcher, Sindy; Sarfo, Fred Stephen; Dompreh, Albert; Cesar, Lucio-Garcia; Knops, Elena; Heger, Eva; Wirtz, Maike; Kaiser, Rolf; Norman, Betty; Odame Phillips, Richard; Feldt, Torsten; Eberhardt, Kirsten Alexandra

In the post-polio eradication era, increasing attention is given to non-polio enteroviruses. Most of the data about enteroviruses in sub-Saharan Africa are related to acute flaccid paralysis surveillance and target the ...

2020-02-28Zeitschriftenartikel

Whole genome sequencing reveals extended natural transformation in Campylobacter impacting diagnostics and the pathogens adaptive potential

Golz, Julia C.; Epping, Lennard; Knüver, Marie-Theres; Borowiak, Maria; Hartkopf, Felix; Deneke, Carlus; Malorny, Burkhard; Semmler, Torsten; Stingl, Kerstin

Campylobacter is the major bacterial agent of human gastroenteritis worldwide and represents a crucial global public health burden. Species differentiation of C. jejuni and C. coli and phylogenetic analysis is challenged ...

2020-03-03Zeitschriftenartikel

Four European Salmonella Typhimurium datasets collected to develop WGS-based source attribution methods

Munck, Nanna; Leekitcharoenphon, Pimlapas; Litrup, Eva; Kaas, Rolf; Meinen, Anika; Guillier, Laurent; Tang, Yue; Malorny, Burkhard; Palma, Federica; Borowiak, Maria; Gourmelon, Michèle; Simon, Sandra; Banerji, Sangeeta; Petrovska, Liljana; Dallman, Timothy J.; Hald, Tine

Zoonotic Salmonella causes millions of human salmonellosis infections worldwide each year. Information about the source of the bacteria guides risk managers on control and preventive strategies. Source attribution is the ...

2020-02-18Zeitschriftenartikel

Travel-associated neurological disease terminated in a postmortem diagnosed atypical HSV-1 encephalitis after high-dose steroid therapy – a case report

Osterman, Andreas; Ruf, Viktoria C.; Domingo, Christina; Nitsche, Andreas; Eichhorn, Peter; Zimmermann, Hanna; Seelos, Klaus; Zange, Sabine; Dimitriadis, Konstantinos; Pfister, Hans-Walter; Thye, Thorsten; Giese, Armin; Tappe, Dennis; Böhm, Stephan

Background Human encephalitis can originate from a variety of different aetiologies, of which infection is the most common one. The diagnostic work-up is specifically challenging in patients with travel history since a ...

2020-02-18Zeitschriftenartikel

Upregulation of SMYD3 and SMYD3 VNTR 3/3 polymorphism increase the risk of hepatocellular carcinoma

Thanh Binh, Mai; Xuan Hoan, Nghiem; Phuong Giang, Dao; Van Tong, Hoang; Bock, Claus-Thomas; Wedemeyer, Heiner; Linh Toan, Nguyen; Hong Bang, Mai; Kremsner, Peter G.; Meyer, Christian G.; Huu Song, Le; Velavan, Thirumalaisamy P.

SMYD3 (SET and MYND domain-containing protein 3) is involved in histone modification, which initiates oncogenesis by activating transcription of multiple downstream genes. To investigate associations of variable numbers ...

2020-03-20Zeitschriftenartikel

Modellierung von Beispielszenarien der SARS-CoV-2-Epidemie 2020 in Deutschland

an der Heiden, Matthias; Buchholz, Udo

2020-02-16Zeitschriftenartikel

Risk factors for hospitalized respiratory syncytial virus disease and its severe outcomes

Cai, Wei; Buda, Silke; Schuler, Ekkehard; Hirve, Siddhivinayak; Zhang, Wenqing; Haas, Walter

Introduction Respiratory syncytial virus (RSV) is a major cause of hospital admission for acute lower respiratory tract infection in young children. Objectives We aimed to identify risk factors for hospitalized RSV ...

2019-11-30Zeitschriftenartikel

Comparative Analysis of Roseoloviruses in Humans, Pigs, Mice, and Other Species

Denner, Joachim

Viruses of the genus Roseolovirus belong to the subfamily Betaherpesvirinae, family Herpesviridae. Roseoloviruses have been studied in humans, mice and pigs, but they are likely also present in other species. This is the ...

2020-02-28Zeitschriftenartikel

Population-based food consumption survey as an additional tool for foodborne outbreak investigations, Germany, 2017

Rosner, Bettina M.; Meinen, Anika; Schmich, Patrick; Zeisler, Marie-Luise; Stark, Klaus

We conducted a food consumption survey in the general adult population of 18 years and older in Germany to obtain data on the frequency of consumption of food items that caused foodborne disease outbreaks in the past. A ...

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