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Now showing items 731-740 of 11373

2017-04-12Zeitschriftenartikel

Prevalence and genotype distribution of hepatitis delta virus among chronic hepatitis B carriers in Central Vietnam

Nguyen, Hung Minh; Sy, Bui Tien; Trung, Nguyen Thanh; Hoan, Nghiem Xuan; Wedemeyer, Heiner; Velavan, Thirumalaisamy P.; Bock, Thomas

Hepatitis D virus (HDV) infection plays an important role in liver diseases. However, the molecular epidemiology and impact of HDV infection in chronic hepatitis B (CHB) remain uncertain in Vietnam. This cross-sectional ...

2017-04-04Zeitschriftenartikel

Evaluation of the immunogenicity and safety of different doses and formulations of a broad spectrum influenza vaccine (FLU-v) developed by SEEK: study protocol for a single-center, randomized, double-blind and placebo-controlled clinical phase IIb trial

Doorn, Eva van; Pleguezuelos, Olga; Liu, Heng; Fernandez, Ana; Bannister, Robin; Stoloff, Gregory; Oftung, Fredrik; Norley, Stephen; Huckriede, Anke; Frijlink, Henderik W.; Hak, Eelko

Background: Current influenza vaccines, based on antibodies against surface antigens, are unable to provide protection against newly emerging virus strains which differ from the vaccine strains. Therefore the population ...

2017-04-04Zeitschriftenartikel

Typical patterns of modifiable health risk factors (MHRFs) in elderly women in Germany: results from the cross-sectional German Health Update (GEDA) study, 2009 and 2010

Jentsch, Franziska; Allen, Jennifer; Fuchs, Judith; Lippe, Elena von der

Background: Modifiable health risk factors (MHRFs) significantly affect morbidity and mortality rates and frequently occur in specific combinations or risk clusters. Using five MHRFs (smoking, high-risk alcohol consumption, ...

2017-05-30Zeitschriftenartikel

Structural and functional dissection reveals distinct roles of Ca2+-binding sites in the giant adhesin SiiE of Salmonella enterica

Peters, Britta; Stein, Johanna; Klingl, Stefan; Sander, Nathalie; Sandmann, Achim; Taccardi, Nicola; Sticht, Heinrich; Gerlach, Roman G.; Muller, Yves A.; Hensel, Michael

The giant non-fimbrial adhesin SiiE of Salmonella enterica mediates the first contact to the apical site of epithelial cells and enables subsequent invasion. SiiE is a 595 kDa protein composed of 53 repetitive bacterial ...

2017-06-15Zeitschriftenartikel

Overweight and obesity among adults in Germany

Schienkiewitz, Anja; Mensink, Gert; Kuhnert, Ronny; Lange, Cornelia

Body weight and height, as well as associated indicators like overweight and obesity, are widespread factors used to describe the health of a population. Over the past decades, the prevalence of overweight and obesity has ...

2017-06-15Zeitschriftenartikel

Alcohol consumption among adults in Germany: heavy episodic drinking

Lange, Cornelia; Manz, Kristin; Kuntz, Benjamin

Consuming harmful amounts of alcohol is considered a contributing factor in over 200 diseases. Heavy episodic drinking is a particularly risky drinking pattern, with possible consequences such as acute alcohol intoxication, ...

2017-06-15Zeitschriftenartikel

Work-related physical activity among adults in Germany

Finger, Jonas D.; Mensink, Gert; Lange, Cornelia; Manz, Kristin

In GEDA 2014/2015-EHIS the prevalence of work-related physical activity was estimated based on respondents’ self-reported data. 47.5% of women and 47.2% of men mostly sit or stand during work. The highest proportion of ...

2017-06-15Zeitschriftenartikel

Vegetable consumption among adults in Germany

Mensink, Gert; Schienkiewitz, Anja; Lange, Cornelia

Vegetables are part of a healthy diet and can help prevent various chronic diseases. According to the GEDA 2014/2015- EHIS study, 40.4% of women and 23.9% of men eat vegetables on a daily basis. The proportion of women ...

2017-06-15Zeitschriftenartikel

Trends in tobacco sales in Germany

Kuntz, Benjamin; Zeiher, Johannes; Lange, Cornelia; Lampert, Thomas

Based on data from the tobacco tax revenue statistics provided by Germany’s Federal Statistical Office, we analyse the development of sales of various tobacco products. In 2016, per capita consumption of tobacco products ...

2017-07-06Zeitschriftenartikel

Decreasing seroprevalence of herpes simplex virus type 1 and type 2 in Germany leaves many people susceptible to genital infection: time to raise awareness and enhance control

Korr, Gerit; Thamm, Michael; Czogiel, Irina; Poethko-Mueller, Christina; Bremer, Viviane; Jansen, Klaus

Background: Herpes simplex infections (HSV1/2) are characterized by recurrent symptoms, a risk of neonatal herpes, and the facilitation of HIV transmission. In Germany, HSV1/2 infections are not notifiable and data are ...

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