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Now showing items 761-770 of 11373

2016-09-26Zeitschriftenartikel

Environmental Noise Annoyance and Mental Health in Adults: Findings from the Cross-Sectional German Health Update (GEDA) Study 2012

Hammersen, Friederike; Niemann, Hildegard; Hoebel, Jens

The health implications of environmental noise, especially cardiovascular effects, have been studied intensively. Research on associations between noise and mental health, however, has shown contradictory results. The ...

2016-11-21Zeitschriftenartikel

Validation of the German Diabetes Risk Score among the general adult population: findings from the German Health Interview and Examination Surveys

Paprott, Rebecca; Mühlenbruch, Kristin; Mensink, Gert; Thiele, Silke; Schulze, Matthias B.; Scheidt-Nave, Christa; Heidemann, Christin

Objective: To evaluate the German Diabetes Risk Score (GDRS) among the general adult German population for prediction of incident type 2 diabetes and detection of prevalent undiagnosed diabetes. Methods: The longitudinal ...

2016-11-30Zeitschriftenartikel

Assessing the feasibility of fly based surveillance of wildlife infectious diseases

Hoffmann, Constanze; Stockhausen, Melanie; Merkel, Kevin; Calvignac-Spencer, Sébastien; Leendertz, Fabian H.

Monitoring wildlife infectious agents requires acquiring samples suitable for analyses, which is often logistically demanding. A possible alternative to invasive or non-invasive sampling of wild-living vertebrates is the ...

2016-09-09Zeitschriftenartikel

Predicting 10-Year Risk of Fatal Cardiovascular Disease in Germany: An Update Based on the SCORE-Deutschland Risk Charts

Rücker, Viktoria; Keil, Ulrich; Fitzgerald, Anthony P.; Malzahn, Uwe; Prugger, Christof; Ertl, Georg; Heuschmann, Peter U.; Neuhauser, Hannelore

Estimation of absolute risk of cardiovascular disease (CVD), preferably with population-specific risk charts, has become a cornerstone of CVD primary prevention. Regular recalibration of risk charts may be necessary due ...

2016-11-21Zeitschriftenartikel

STI tests and proportion of positive tests in female sex workers attending local public health departments in Germany in 2010/11

Bremer, Viviane; Haar, Karin; Gassowski, Martyna; Hamouda, Osamah; Nielsen, Stine

Background: In Germany, local public health departments (LPHD) are required to offer low-threshold access to confidential counselling and testing for sexually transmitted infections (STI) for sex workers. We collected ...

2016-12-02Zeitschriftenartikel

Virus Safety of Xenotransplantation: Prevalence of Porcine Circovirus 2 (PCV2) in Pigs

Heinze, Julian; Plotzki, Elena; Denner, Joachim

Porcine circovirus 2 (PCV2) is the causative agent of a whole series of diseases in pigs, called PCV2 diseases (PCVD). The most relevant of them is the systemic disease (PCV2-SD), formerly called post weaning multi ...

2016-01-21Zeitschriftenartikel

Genome Sequences of Murine Pneumotropic Virus (Polyomaviridae) Detected in Wild House Mice (Mus musculus)

Salem, Nicole Ben; Moens, Ugo; Ehlers, Bernhard

Using generic PCR, we identified a variant of murine pneumotropic virus (MptV) (family Polyomaviridae) in 3 wild house mice (Mus musculus). The fully amplified and sequenced genomes display considerable differences from ...

2017-02-03Zeitschriftenartikel

Host cell interactions of outer membrane vesicle-associated virulence factors of enterohemorrhagic Escherichia coli O157: Intracellular delivery, trafficking and mechanisms of cell injury

Bielaszewska, Martina; Rüter, Christian; Bauwens, Andreas; Greune, Lilo; Jarosch, Kevin-André; Steil, Daniel; Zhang, Wenlan; He, Xiaohua; Lloubes, Roland; Fruth, Angelika; Kim, Kwang Sik; Schmidt, M. Alexander; Dobrindt, Ulrich; Mellmann, Alexander; Karch, Helge

Outer membrane vesicles (OMVs) are important tools in bacterial virulence but their role in the pathogenesis of infections caused by enterohemorrhagic Escherichia coli (EHEC) O157, the leading cause of life-threatening ...

2017-02-10Zeitschriftenartikel

Participatory epidemiology: the contribution of participatory research to epidemiology

Bach, Mario; Jordan, Susanne; Hartung, Susanne; Santos-Hövener, Claudia; Wright, Michael T.

Background: Epidemiology has contributed in many ways to identifying various risk factors for disease and to promoting population health. However, there is a continuing debate about the ability of epidemiology not only ...

2017-02-17Zeitschriftenartikel

Scarless deletion of up to seven methyl-accepting chemotaxis genes with an optimized method highlights key function of CheM in Salmonella Typhimurium

Hoffmann, Stefanie; Schmidt, Christiane; Walter, Steffi; Bender, Jennifer K.; Gerlach, Roman G.

Site-directed scarless mutagenesis is an essential tool of modern pathogenesis research. We describe an optimized two-step protocol for genome editing in Salmonella enterica serovar Typhimurium to enable multiple sequential ...

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