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2017-03-29Zeitschriftenartikel

Predicting late-onset sepsis by routine neonatal screening for colonisation by gram-negative bacteria in neonates at intensive care units: a protocol for a systematic review

Harder, Thomas; Seidel, Juliane; Eckmanns, Tim; Weiss, Bettina; Haller, Sebastian

Introduction: Hospitals conduct extensive screening procedures to assess colonisation of the body surface of neonates by gram-negative bacteria to avoid complications like late-onset sepsis. However, the benefits of these ...

2017-06-06Zeitschriftenartikel

Changing educational inequalities in sporting inactivity among adults in Germany: a trend study from 2003 to 2012

Hoebel, Jens; Finger, Jonas; Kuntz, Benjamin; Kroll, Lars Eric; Manz, Kristin; Lange, Cornelia; Lampert, Thomas

Background: Social inequalities in health can be explained in part by the social patterning of leisure-time physical activity, such as non-participation in sports. This study is the first to explore whether absolute and ...

2017-05-19Zeitschriftenartikel

Varicella-zoster virus seroprevalence in children and adolescents in the pre-varicella vaccine era, Germany

Wiese-Posselt, Miriam; Siedler, Anette; Mankertz, Annette; Sauerbrei, Andreas; Hengel, Hartmut; Wichmann, Ole; Poethko-Müller, Christina

Background: In 2004, universal childhood varicella vaccination was introduced in Germany. We aimed to determine the age-specific prevalence of anti-varicella zoster virus (VZV) IgG-antibodies among children in the ...

2017-06-02Zeitschriftenartikel

Characteristics of participants in a randomized trial of an Internet intervention for depression (EVIDENT) in comparison to a national sample (DEGS1)

Späth, Christina; Hapke, Ulfert; Maske, Ulrike; Schröder, Johanna; Moritz, Steffen; Berger, Thomas; Meyer, Björn; Rose, Matthias; Nolte, Sandra; Klein, Jan Philipp

Background: While the efficacy of Internet interventions for depression has been demonstrated in numerous studies, there is concern that the participants in these studies may systematically differ from depressed subjects ...

2017-06-10Zeitschriftenartikel

Physical health-related quality of life in relation to metabolic health and obesity among men and women in Germany

Truthmann, Julia; Mensink, Gert; Bosy-Westphal, Anja; Hapke, Ulfert; Scheidt-Nave, Christa; Schienkiewitz, Anja

Background: This study examined sex-specific differences in physical health-related quality of life (HRQoL) across subgroups of metabolic health and obesity. We specifically asked whether (1) obesity is related to lower ...

2017-05-25Zeitschriftenartikel

Ongoing haemolytic uraemic syndrome (HUS) outbreak caused by sorbitol-fermenting (SF) Shiga toxinproducing Escherichia coli (STEC) O157, Germany, December 2016 to May 2017

Vygen-Bonnet, Sabine; Rosner, Bettina; Wilking, Hendrik; Fruth, Angelika; Prager, Rita; Kossow, A.; Lang, Christina; Simon, Sandra; Seidel, Juliane; Faber, Mirko; Schielke, Anika; Michaelis, Kai; Holzer, Alexandra; Kamphausen, R.; Kalhöfer, D.; Thole, S.; Mellmann, Alexander; Flieger, Antje; Stark, Klaus

We report an ongoing, protracted and geographically dispersed outbreak of haemolytic uraemic syndrome (HUS) and gastroenteritis in Germany, involving 30 cases since December 2016. The outbreak was caused by the sorbitol-fermenting ...

2017-05-18Zeitschriftenartikel

Identification of a Novel Hepatitis E Virus Genotype 3 Strain Isolated from a Chronic Hepatitis E Virus Infection in a Kidney Transplant Recipient in Switzerland

Wang, Bo; Harms, Dominik; Hofmann, Jörg; Ciardo, Diana; Kneubühl, Agnes; Bock, Thomas

Hepatitis E virus genotype 3 (HEV-3) is the causal pathogen of chronic hepatitis E. We report here the full-length genome sequence of an HEV-3 strain, isolated from a kidney transplant recipient in Switzerland (SW/16-0282). ...

2017-06-08Zeitschriftenartikel

Genome Sequence of Paracoccus contaminans LMG 29738T, Isolated from a Water Microcosm

Aurass, Philipp; Karste, Susanne; Trost, Eva; Glaeser, Stefanie P.; Kämpfer, Peter; Flieger, Antje

We announce here the complete genome sequence of Paracoccus contaminans LMG 29738T, which we recently isolated from a contaminated water microcosm. The genome consists of a 2.94-Mb chromosome and a 94-kb plasmid. To our ...

2017-05-12Zeitschriftenartikel

A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH

Osman, Mohamed; Mistry, Anoop; Keding, Ada; Gabe, Rhian; Cook, Elizabeth; Forrester, Sarah; Wiggins, Rebecca; Marco, Stefania Di; Colloca, Stefano; Siani, Loredana; Cortese, Riccardo; Smith, Deborah F.; Aebischer, Toni; Kaye, Paul M.

Background: Visceral leishmaniasis (VL or kala azar) is the most serious form of human leishmaniasis, responsible for over 20,000 deaths annually, and post kala azar dermal leishmaniasis (PKDL) is a stigmatizing skin ...

2016-03-17Zeitschriftenartikel

Todesfälle durch Influenzapandemien in Deutschland 1918 bis 2009

Buchholz, Udo; Buda, Silke; Reuß, Annicka; Haas, Walter; Uphoff, Helmut

Hintergrund und Zielstellung: Schätzungen der Anzahl der Verstorbenen infolge der Influenzapandemien des 20. und 21. Jahrhunderts (1918/1919, 1957/1958, 1968–1970 und 2009) sind weltweit und auch für Deutschland eine ...

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