The edoc-Server, the insitutional digital repository system of the Robert Koch Institute captures, stores, indexes, preserves, and distributes digital research material. http://edoc.rki.de:80 2026-06-18T11:47:36Z 2026-06-18T11:47:36Z STAKOB http://edoc.rki.de/176904/10630.4 2026-06-17T12:57:47Z 2023-03-31T00:00:00Z

Hinweise zu Therapie und Prophylaxe von Ebolafieber, engl. Ebola Disease (EBOD) STAKOB

2023-03-31T00:00:00Z Kersjes, Christina Peitz, Diana Birgel, Vera Wachtler, Benjamin Cohrdes, Caroline http://edoc.rki.de/176904/13765 2026-06-17T11:27:48Z 2026-06-17T00:00:00Z

Perceived stress and coping among adults in Germany: results from the Health in Germany panel 2024 Kersjes, Christina; Peitz, Diana; Birgel, Vera; Wachtler, Benjamin; Cohrdes, Caroline Background: Stress and coping are key determinants of mental health. However, representative data for Germany remain scarce. This study provides population-based findings on the prevalence of perceived stress and coping as well as on their association. Methods: Data were derived from the representative study series ‘Health in Germany’ conducted by the Robert Koch Institute (wave 2024; n = 27,102; 51.1 % women; age range: 18 – 99 years). Descriptive analyses of stress (Perceived Stress Scale; PSS-10) and coping (Short Adult Coping Scale; SACS-16) were conducted by gender, age, and education, as well as regression analyses examining their associations. Results: Approximately 20 % of respondents showed elevated stress levels, particularly women, individuals of working age, and those with low or medium formal education. Problem solving, proactive coping, and coping flexibility were associated with lower perceived stress, whereas repression and wishful thinking were associated with higher perceived stress. Differences in coping strategies were observed primarily across age groups. Conclusions: The findings underscore the public health relevance of stress and indicate potential approaches for preventive measures by promoting suitable and target-group-specific coping strategies.

2026-06-17T00:00:00Z Kersjes, Christina Peitz, Diana Birgel, Vera Wachtler, Benjamin Cohrdes, Caroline http://edoc.rki.de/176904/13764 2026-06-17T10:57:46Z 2026-06-17T00:00:00Z

Wahrgenommener Stress und Coping bei Erwachsenen in Deutschland: Ergebnisse aus dem Panel „Gesundheit in Deutschland“ 2024 Kersjes, Christina; Peitz, Diana; Birgel, Vera; Wachtler, Benjamin; Cohrdes, Caroline Hintergrund: Stress und Coping sind zentrale Determinanten der psychischen Gesundheit, jedoch liegen für Deutschland kaum repräsentative Daten vor. Diese Studie liefert bevölkerungsbezogene Ergebnisse zur Häufigkeit von Stress, Coping und deren Zusammenhang. Methode: Datengrundlage war die repräsentative Studienreihe „Gesundheit in Deutschland“ des Robert Koch-Instituts (Welle 2024; n = 27.102, 51,1 % Frauen, 18 – 99 Jahre). Es erfolgten deskriptive Analysen von Stress (Perceived Stress Scale; PSS-10) und Coping (Short Adult Coping Scale; SACS-16) nach Geschlecht, Alter und Bildung sowie Regressionsanalysen zu deren Zusammenhängen. Ergebnisse: Etwa 20 % der Befragten wiesen eine erhöhte Stressbelastung auf, insbesondere Frauen, Personen im erwerbsfähigen Alter und Personen mit niedrigen und mittleren formalen Bildungsabschlüssen. Problemlösen, Proaktives Coping und Coping-Flexibilität waren mit geringerem, Verdrängung und Wunschdenken mit höherem Stresserleben assoziiert. Unterschiede in Copingstrategien zeigten sich vor allem nach Altersgruppen. Schlussfolgerungen: Die Ergebnisse unterstreichen die Public-Health-Relevanz von Stress und weisen auf mögliche Ansatzpunkte für Präventionsmaßnahmen durch die Förderung geeigneter und zielgruppenspezifischer Copingstrategien hin.

2026-06-17T00:00:00Z PharmaLex GmbH (part of Cencora Inc.) http://edoc.rki.de/176904/12927.2 2026-06-15T12:13:14Z 2026-04-01T00:00:00Z

Treatment Pathways and Clinical Characteristics Among Patients with Metastatic Breast Cancer in Germany: A Retrospective Descriptive Analysis with Data from 2020 to 2023 (Datenaktualisierung bis Diagnosejahr 2024) PharmaLex GmbH (part of Cencora Inc.) Breast cancer is the most common cancer among women worldwide and represents a significant health challenge. It is caused by uncontrolled growth of breast tissue cells and can metastasize to other parts of the body if it is not detected and treated in time. Breast cancer treatment is tailored to the individual and depends on various factors, including type and stage of the tumor, hormone receptor status, and the patient's overall health. For patients with metastatic breast cancer (mBC) the primary treatment modalities include systemic drug therapies such as hormone therapy, chemotherapy, targeted drugs, and immunotherapy. These treatments aim to reduce the tumor size, alleviate symptoms, and prolong survival. This study will address the gap in our understanding of the real-world treatment patterns and outcomes of mBC in Germany. The objectives of this study are: • Conduct a descriptive analysis of incident mBC patients, focusing on their demographic and clinical characteristics. • Examine the HER2 status distribution and its impact on treatment decisions. • Classify breast cancer cases according to ICD-10 and ICD-O. • Describe treatment patterns of all incident mBC patients. • Analyze overall survival, progression-free survival, and response rate of mBC patients. This retrospective study will utilize data from the German Centre for Cancer Registry Data (Zentrum für Krebsregisterdaten, ZfKD) at the Robert Koch Institute (RKI), covering diagnosis years 2020 to 2023. Patients with newly diagnosed mBC within this period will be included. Exclusion criteria will involve incomplete records and non-metastatic cases. Statistical analysis will be conducted using appropriate methods and software to examine treatment outcomes and trends over time, such as descriptive statistics and Kaplan-Meier for overall survival. The choice of statistical techniques will be further specified based on the data availability. The study aims to provide valuable information for patients and various stakeholders involved in mBC management. This will be achieved by improving the understanding of the treatment pathways as well as demographic and clinical characteristics of mBC patients in Germany.

2026-04-01T00:00:00Z