http://edoc.rki.de/176904/43 Tue, 20 Oct 2026 03:35:58 GMT 2026-10-20T03:35:58Z http://edoc.rki.de/176904/14038 Beschluss und wissenschaftliche Begründung der STIKO zur zoonotischen Influenza-A(H5)-Impfung Askar, M.; Külper-Schieck, W.; Schäfer, R.; Flasche, S.; Kwetkat, A.; Müller, B.; Röbl-Mathieu, M.; Tabatabai, J.; Lange, B. Aviäre Influenza-Viren des Subtyps A(H5) zirkulieren weltweit endemisch in wild lebenden Wasservögeln und haben sich zunehmend in Geflügelbeständen sowie in einer wachsenden Zahl von Säugetierspezies etabliert. Nach Einschätzung des ECDC besteht für beruflich exponierte Personengruppen ein geringes bis moderates Infektionsrisiko. Zudem kann grundsätzlich nicht ausgeschlossen werden, dass zoonotische A(H5)-Viren bei humanen Infektionen Adaptationen zur nachhaltigen Mensch-zu-Mensch-Übertragung entwickeln. Die STIKO empfiehlt daher Personen, die gezielte Tätigkeiten mit Influenza-A(H5)-Viren gemäß BioStoffV ausüben oder die in der Tierseuchen-/Ausbruchsbekämpfung involviert sind, eine Grundimmunisierung gegen Influenza-A(H5). Thu, 15 Oct 2026 00:00:00 GMT http://edoc.rki.de/176904/14038 2026-10-15T00:00:00Z http://edoc.rki.de/176904/14034 Author Correction: Analysis of mutations in pncA reveals non-overlapping patterns among various lineages of Mycobacterium tuberculosis Baddam, Ramani; Kumar, Narender; Wieler, Lothar H.; Kumar Lankapalli, Aditya; Ahmed, Niyaz; Peacock, Sharon J. Tue, 15 May 2018 00:00:00 GMT http://edoc.rki.de/176904/14034 2018-05-15T00:00:00Z http://edoc.rki.de/176904/14033 Erratum to “Predominance of influenza A(H3N2) virus genetic subclade 3C.2a1 during an early 2016/17 influenza season in Europe – Contribution of surveillance data from World Health Organization (WHO) European region to the WHO vaccine composition consultation for northern hemisphere 2017/18” [Vaccine 35 (2017) 4828–4835] Melidou, Angeliki; Broberg, Eva; Buda, Silke Sat, 21 Apr 2018 00:00:00 GMT http://edoc.rki.de/176904/14033 2018-04-21T00:00:00Z http://edoc.rki.de/176904/14030 Changes in prevalence of psychotropic drug use and alcohol consumption among the elderly in Germany: results of two National Health Interview and Examination Surveys 1997-99 and 2008-11 Wolf, Ingrid-Katharina; Du, Yong; Knopf, Hiltraud Background Psychotropic drug use and alcohol consumption among older adults need to be monitored over time as their use or combined use bears risks of harms. Representative data on changes in prevalence, patterns and co-relates of substance use are lacking in Germany. Methods Participants were older adults (60–79 years) from two German National Health Surveys: 1997–99 (GNHIES98, N = 1,606) and 2008-11 (DEGS1, N = 2,501). Included were drugs acting on the nervous system used during the last 7 days. Alcohol consumption was measured by frequency (daily drinking) and quantity (risky drinking: ≥20/10 g/day alcohol for men/women). Changes in prevalence adjusted for potential socio-economic and health-related confounders were calculated by logistic regression models approximated by the SAS LSMEANS statement. Results The prevalence of overall psychotropic drug use (20.5% vs. 21.4%) remained constant between the two surveys. Significant changes were observed in the use of some psychotropics (all GNHIES98 vs. DEGS1): Synthetic antidepressants (3.9% vs. 6.9%), St. John’s wort (2.9% vs. 1.1%), benzodiazepines (3.7% vs. 2.5%), benzodiazepine related drugs (0.2% vs. 0.8%), narcotic analgesics (3.0% vs. 4.1%), anti-dementia drugs (2.2% vs. 4.2%) and anti-epileptics (1.0% vs. 2.3%). Significant changes were also observed in long-term use of synthetic anti-depressants (3.2% vs. 5.9%), St. John’s wort (2.0% vs. 0.6%) and opioid analgesics (1.0% vs. 2.2%). Further, we found significant changes in benzodiazepines use (3.3% vs. 1.4%) among men, opioids use (2.9% vs. 7.3%) among people with a lower social status, and overall psychotropics (26.8% vs. 32.5%) as well as opioids use (4.4% vs. 8.1%) among those with a worse health status. Moderate alcohol consumption increased significantly (58.0% vs. 66.9%). Risky drinking remained unchanged (16.6% vs. 17.0%). In spite of significant increases in daily alcohol drinking (13.2% vs. 18.4%) psychotropic drug use combined with daily drinking remained unchanged (1.8% vs. 2.7%). Conclusions Although prevalence of overall psychotropic drug use remained stable, changes in the use of some psychotropic drug groups and alcohol consumption patterns have been observed. Further studies are required to investigate resulting health consequences and public health relevance of those outcomes Thu, 09 Mar 2017 00:00:00 GMT http://edoc.rki.de/176904/14030 2017-03-09T00:00:00Z