http://edoc.rki.de/176904/43 Sat, 11 Apr 2026 12:32:30 GMT 2026-04-11T12:32:30Z http://edoc.rki.de/176904/13616 Antimicrobial Resistance Surveillance: Data Harmonisation and Data Selection within Secondary Data Use Bleischwitz, Sinja; Winkelmann, Tristan Salomon; Pfeifer, Yvonne; Fischer, Martin Alexander; Pfennigwerth, Niels; Hammerl, Jens André; Binsker, Ulrike; Hans, Jörg B.; Gatermann, Sören; Käsbohrer, Annemarie; Werner, Guido; Kreienbrock, Lothar Resistance to last-resort antibiotics is a global threat to public health. Therefore, surveillance and monitoring systems for antimicrobial resistance should be established on a national and international scale. For the development of a One Health surveillance system, we collected exemplary data on carbapenem and colistin-resistant bacterial isolates from human, animal, food, and environmental sources. We pooled secondary data from routine screenings, hospital outbreak investigations, and studies on antimicrobial resistance. For a joint One Health evaluation, this study incorporates epidemiological metadata with phenotypic resistance information and molecular data on the isolate level. To harmonise the heterogeneous original information for the intended use, we developed a generic strategy. By defining and categorising variables, followed by plausibility checks, we created a catalogue for prospective data collections and applied it to our dataset, enabling us to perform preliminary descriptive statistical analyses. This study shows the complexity of data management using heterogeneous secondary data pools and gives an insight into the early stages of the development of an AMR surveillance programme using secondary data. Tue, 16 Jul 2024 00:00:00 GMT http://edoc.rki.de/176904/13616 2024-07-16T00:00:00Z http://edoc.rki.de/176904/13613 Determinants of Mental Health Inequalities Among People With Selected Citizenships in Germany Blume, Miriam; Bartig, Susanne; Wollgast, Lina; Koschollek, Carmen; Kajikhina, Katja; Bug, Marleen; Hapke, Ulfert; Hövener, Claudia Objectives: Mental health is essential for overall health and is influenced by different social determinants. The aim of this paper was to examine which determinants are associated with mental health inequalities among people with selected citizenships in Germany. Methods: Data were derived from the multilingual interview survey “German Health Update: Fokus (GEDA Fokus)” among adults with Croatian, Italian, Polish, Syrian, or Turkish citizenship (11/2021–05/2022). Poisson regressions were used to calculate prevalence ratios for symptoms of depression (PHQ-9) and anxiety disorder (GAD-7). Results: Sociodemographic (sex, income, age, household size) and psychosocial (social support and self-reported discrimination) determinants were associated with symptoms of depression and/or anxiety disorder. The prevalence of mental disorders varied most by self-reported discrimination. Conclusion: Our findings suggest mental health inequalities among people with selected citizenships living in Germany. To reduce these, social inequities and everyday discrimination need to be addressed in structural prevention measures as well as in interventions on the communal level. Protective factors (e.g., social support) are also important to reduce mental health inequalities on the individual and community level. Tue, 27 Aug 2024 00:00:00 GMT http://edoc.rki.de/176904/13613 2024-08-27T00:00:00Z http://edoc.rki.de/176904/13612 Temperature as a potential regulator for Ebola virus replication in primary cells from Mops condylurus Bokelmann, Marcel; Riesle-Sbarbaro, Silke A.; Lander, Angelika; Wahlbrink, Annette; Groschup, Martin H.; Balkema-Buschmann, Anne; Couacy-Hymann, Emmanuel; Prescott, Joseph; Kurth, Andreas Introduction: For more than 40 years, outbreaks of ebolavirus disease have been documented, but the natural reservoir(s) of ebolaviruses remain unknown. However, recent studies provide evidence that the Angolan free-tailed bat (Mops condylurus), an insectivorous bat belonging to the family Molossidae, is a likely ebolavirus reservoir. Being a heterothermic species, M. condylurus bats are highly tolerant to variations in ambient temperatures, and therefore are capable of living under a broad range of climatic and environmental conditions by using adaptive thermoregulation. Body core temperatures as low as 12.0°C have been measured during winter, while increased body temperatures were observed in their hot roosts or during flight, reaching temperatures typical of fever in most other mammalian species. Methods: Here, we investigated the impact of temperature fluctuations between 27°C and 42°C on Ebola virus (EBOV) survival and replication kinetics in cells from M. condylurus using qRT-PCR. Results: We found that primary cells derived from M. condylurus, similar to the bats in their natural environment, were highly tolerant to temperature variations. EBOV replication was temperature-dependent, showing a strong reduction of replication efficiency at low temperature. Discussion: We therefore conclude, that heterothermy might be involved in balancing the level of EBOV replication and thereby be a key factor for tolerating EBOV infections in vivo. Fri, 09 Aug 2024 00:00:00 GMT http://edoc.rki.de/176904/13612 2024-08-09T00:00:00Z http://edoc.rki.de/176904/13611 Gemeinsam Stark: Übung zu einem Ausbruchsgeschehen im Hamburger Hafen im Rahmen der Pre-Conference des BVÖGD Kongresses 2024 Bäßler, Julian; Bühler, Silja; Schreiber, Jenny; Weidlich, Anna; von Reiswitz, Alexandra; Engel, Peter Tom; Jakubowski, Elke; Jansen, Stephanie; Lühken, Renke; Frank, Christina; Frese, Marie; Kleine-Kampmann, Scarlett Der maritime Sektor ist aufgrund besonderer struktureller Merkmale und zunehmender globaler Mobilität dezidierten Risiken im Bereich übertragbarer Krankheiten ausgesetzt. Zur Minimierung der Ausbreitung endemischer und importierter Krankheitserreger ist ein effektives Vorgehen zur Prävention und zum Management von Infektionsgeschehen an Bord von Schiffen und in Häfen essenziell. Im Rahmen des Projekts „Gesunde Häfen – gemeinsam stark“ wurde ein Pre-Conference-Workshop auf dem BVÖGD-Kongress 2024 durchgeführt. Ein Fokus des Workshops war es, mithilfe von Table-Top-Übungen zum Szenario eines Denguevirus-Ausbruchs im Hamburger Hafen die verschiedenen Rollen der Akteurinnen und Akteure des Öffentlichen Gesundheitsdienstes zu trainieren und dabei Kommunikation, Vernetzung und Schnittstellen zu veranschaulichen. Der Artikel gibt Einblicke in den Prozess von der Konzeptentwicklung bis zur Umsetzung des Workshops und stellt zentrale Lessons Learned der Zusammenarbeit während eines Ausbruchs dar.; The maritime sector is exposed to specific risks related to communicable diseases due to its unique structural characteristics and increasing global mobility. To minimize the spread of endemic and imported pathogens, an effective approach to the prevention and management of infectious disease outbreaks on board ships and in ports is essential. As part of the “Healthy Ports – Strong Together” project, a pre-conference workshop was held at the 2024 BVÖGD Congress. One focus of the workshop was to use tabletop exercises simulating a dengue virus outbreak in the Port of Hamburg to train the various roles of public health service stakeholders, thereby illustrating communication, networking, and collaboration structures. The article provides insights into the process from concept development to the implementation of the workshop and key lessons learned about collaboration during an outbreak. Thu, 09 Apr 2026 00:00:00 GMT http://edoc.rki.de/176904/13611 2026-04-09T00:00:00Z