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2006-09-14Zeitschriftenartikel
Factors contributing to conductance and outcome of specific immunotherapy: Data from the German National Health Interview and Examination Survey 1998
dc.contributor.authorHommers, Leif
dc.contributor.authorEllert, Ute
dc.contributor.authorScheidt-Nave, Christa
dc.contributor.authorLangen, Ute
dc.date.accessioned2023-03-23T07:38:14Z
dc.date.available2023-03-23T07:38:14Z
dc.date.issued2006-09-14none
dc.identifier.urihttp://edoc.rki.de/176904/10864
dc.description.abstractBackground: Allergies are an increasingly relevant public health problem. Specific immunotherapy (sIT) is presently the only causal treatment option. This study aimed to assess the frequency and determinants of sIT use and factors associated with treatment outcome. Methods: A cross-sectional analysis based on data from the German National Health Interview and Examination Survey 1998. Results: 2727 (39.2%) of study participants reported physician-diagnosed allergic disease. Among these, 16.5% (n ¼ 296) stated to have undergone sIT. In this subset 43.4% (n ¼ 129) reported improvement of symptoms, 21.9% (n ¼ 65) had not changed, and 34.6% (n ¼ 102) had discontinued treatment. The majority of patients treated with sIT showed multiple allergic symptoms and sensitisations. Factors significantly correlated with sIT treatment in multivariable analyses included rhinitis, asthma, several sensitisations, higher social status and residence in larger cities. Rhinitis and neurodermatitis were positively, and food allergy was negatively associated with the completion of sIT. No factors predicting improvement due to sIT could retrospectively be identified. Conclusion: Treatment with sIT under ‘real life’ conditions does not exactly follow current clinical guideline recommendations. In addition, patients may be selected for IT by socio-demographic factors. Whether this contributes to considerable discontinuation rates and limited effectiveness as observed here, needs further investigation.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.subjectallergieseng
dc.subjectGerman National Health Interview and Examination Survey 1998eng
dc.subjectspecific immunotherapyeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleFactors contributing to conductance and outcome of specific immunotherapy: Data from the German National Health Interview and Examination Survey 1998none
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/10864-7
local.edoc.container-titleEuropean Journal of Public Healthnone
local.edoc.container-issn1464-360Xnone
local.edoc.pages7none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-publisher-nameOxford University Pressnone
local.edoc.container-volume17none
local.edoc.container-issue3none
dc.description.versionPeer Reviewednone

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