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2020-07-08Zeitschriftenartikel
Diagnostic accuracy of a smartphone bedside test to assess the fixation suppression of the vestibulo-ocular reflex: when nothing else matters
dc.contributor.authorGandor, Florian
dc.contributor.authorTesch, Manfred
dc.contributor.authorNeuhauser, Hannelore
dc.contributor.authorGruber, Doreen
dc.contributor.authorHeinze, Hans-Jochen
dc.contributor.authorEberssbach, Georg
dc.contributor.authorLempert, Thomas
dc.date.accessioned2024-02-08T10:29:35Z
dc.date.available2024-02-08T10:29:35Z
dc.date.issued2020-07-08none
dc.identifier.other10.1007/s00415-020-09947-5
dc.identifier.urihttp://edoc.rki.de/176904/11485
dc.description.abstractObjective Validation of a bedside test to objectify the fixation suppression of the vestibulo-ocular reflex (FS-VOR) in patients with a cerebellar syndrome and healthy controls. Methods The vestibulo-ocular reflex and its fixation suppression were assessed by video-nystagmography (VNG) in 20 healthy subjects (mean age 56 ± 15) and 19 patients with a cerebellar syndrome (mean age 70 ± 11). The statistical cutoff delineating normal from pathological FS-VOR was determined at the 2.5th percentile of the normal distribution of the healthy cohort. VNG was then compared to a bedside test, where eye movements were recorded with a smartphone while patients were rotated on a swivel chair at a defined speed and amplitude. These videos were rated as normal or pathological FS-VOR by six blinded raters, and results compared to VNG. Results VNG in healthy controls showed FS-VOR with a reduction of nystagmus beats by 95.0% ± 7.2 (mean ± SD). The statistical cutoff was set at 80.6%. Cerebellar patients reduced nystagmus beats by only 26.3% ± 25.1. Inter-rater agreement of the smartphone video ratings was 85%. The sensitivity of the video ratings to detect an impaired FS-VOR was 99%, its specificity 92%. Inter-test agreement was 91%. Conclusion The smartphone bedside test is an easily performed, reliable, sensitive, specific, and inexpensive alternative for assessing FS-VOR.eng
dc.language.isoengnone
dc.publisherRobert Koch-Institut
dc.rights(CC BY 3.0 DE) Namensnennung 3.0 Deutschlandger
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/de/
dc.subjectvestibulo-ocular reflexeng
dc.subjectbedside testeng
dc.subjectfixation suppression of the vestibulo-ocular reflexeng
dc.subjectcerebellar syndromeeng
dc.subject.ddc610 Medizin und Gesundheitnone
dc.titleDiagnostic accuracy of a smartphone bedside test to assess the fixation suppression of the vestibulo-ocular reflex: when nothing else mattersnone
dc.typearticle
dc.identifier.urnurn:nbn:de:0257-176904/11485-7
dc.type.versionupdatedVersionnone
local.edoc.container-titleJournal of Neurologynone
local.edoc.container-issn1432-1459none
local.edoc.pages5none
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://link.springer.com/journal/415none
local.edoc.container-publisher-nameSpringer Naturenone
local.edoc.container-volume267none
local.edoc.container-reportyear2020none
local.edoc.container-firstpage2159none
local.edoc.container-lastpage2163none
dc.description.versionPeer Reviewednone

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