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Origin Detection During Food-borne Disease Outbreaks – A Case Study of the 2011 EHEC/HUS Outbreak in Germany
dc.contributor.authorManitz, Juliane
dc.contributor.authorKneib, Thomas
dc.contributor.authorSchlather, Martin
dc.contributor.authorHelbing, Dirk
dc.contributor.authorBrockmann, Dirk
dc.date.accessioned2018-05-07T17:36:12Z
dc.date.available2018-05-07T17:36:12Z
dc.date.created2014-04-04
dc.date.issued2014-04-01none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reTPwHNJv3ECI/PDF/28aKd5so0JzMM.pdf
dc.identifier.urihttp://edoc.rki.de/176904/1855
dc.description.abstractThe key challenge during food-borne disease outbreaks, e.g. the 2011 EHEC/HUS outbreak in Germany, is the design of efficient mitigation strategies based on a timely identification of the outbreak’s spatial origin. Standard public health procedures typically use case-control studies and tracings along food shipping chains. These methods are time-consuming and suffer from biased data collected slowly in patient interviews. Here we apply a recently developed, network-theoretical method to identify the spatial origin of food-borne disease outbreaks. Thereby, the network captures the transportation routes of contaminated foods. The technique only requires spatial information on case reports regularly collected by public health institutions and a model for the underlying food distribution network. The approach is based on the idea of replacing the conventional geographic distance with an effective distance that is derived from the topological structure of the underlying food distribution network. We show that this approach can efficiently identify most probable epicenters of food-borne disease outbreaks. We assess and discuss the method in the context of the 2011 EHEC epidemic. Based on plausible assumptions on the structure of the national food distribution network, the approach can correctly localize the origin of the 2011 German EHEC/HUS outbreak.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut
dc.subject.ddc610 Medizin
dc.titleOrigin Detection During Food-borne Disease Outbreaks – A Case Study of the 2011 EHEC/HUS Outbreak in Germany
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10036064
dc.identifier.doi10.1371/currents.outbreaks.f3fdeb08c5b9de7c09ed9cbcef5f01f2
dc.identifier.doihttp://dx.doi.org/10.25646/1780
local.edoc.container-titlePLoS Current Outbreaks
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://currents.plos.org/outbreaks/article/origin-detection-during-food-borne-disease-outbreaks-a-case-study-of-the-2011-ehechus-outbreak-in-germany-2/
local.edoc.container-publisher-namePublic Library of Science

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