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2014-08-14Zeitschriftenartikel DOI: 10.1186/1471-2458-14-845
A multicentre sero-behavioural survey for hepatitis B and C, HIV and HTLV among people who inject drugs in Germany using respondent driven sampling
dc.contributor.authorZimmermann, Ruth
dc.contributor.authorMarcus, Ulrich
dc.contributor.authorSchäffer, Dirk
dc.contributor.authorLeicht, Astrid
dc.contributor.authorWenz, Benjamin
dc.contributor.authorNielsen, Stine
dc.contributor.authorSantos-Hövener, Claudia
dc.contributor.authorRoss, Stefan
dc.contributor.authorStambouli, Oumaima
dc.contributor.authorRatsch, Boris A.
dc.contributor.authorBannert, Norbert
dc.contributor.authorBock, Thomas
dc.contributor.authorKücherer, Claudia
dc.contributor.authorHamouda, Osamah
dc.date.accessioned2018-05-07T17:52:57Z
dc.date.available2018-05-07T17:52:57Z
dc.date.created2014-09-12
dc.date.issued2014-08-14none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reTkP0V6c0aps/PDF/26gghdZDX0JB.pdf
dc.identifier.urihttp://edoc.rki.de/176904/1945
dc.description.abstractBackground: People who inject drugs are at high risk for hepatitis B, hepatitis C and HIV. HTLV was reported by neighboring countries to be prevalent in this population, but the situation for Germany is unclear. To generate seroprevalence and related behavioural data and to enhance prevention efforts against these infections for drug users in Germany, a multicentre sero- and behavioural survey was initiated. People who inject drugs are not well reached by services for testing and counselling for blood-borne infections in Germany. An interventional part of the study is intended to prove feasibility and acceptance of testing and counselling in low-threshold drop-in settings. Methods/Design: Between May 2011 and March 2015, eligible participants (persons having injected drugs within the last 12 months, aged 16 years+, and living in the study city) are recruited by respondent driven sampling, using low-threshold drop-in facilities as study-sites in eight German cities with large drug scenes. Calculated sample size is 2,033 participants. Capillary blood samples collected as dried blood spots are anonymously tested for serological and molecular markers of hepatitis B and C, HIV, and HTLV I and II. A detailed face-to-face-interview about hepatitis- and HIV-related knowledge, former testing, imprisonment, sexual and injecting risk behaviour is conducted with participants. Staff is trained to offer pre- and post-test-counselling of blood-borne infections and HIV rapid testing to participants. Discussion: We chose respondent driven sampling for recruitment of participants to improve representativeness of results. Persons, who are not reached by the facility where the study is conducted, are aimed to be included by recruitment through their personal social network of injecting drug users. To reduce differential biases in the questions on knowledge of transmission and prevention of infections, we present true statements on hepatitis B, C and HIV, their possible routes of transmission and measures of prevention to participants. Participants are told that the statements are true and are asked to answer if they knew this fact already or if it is new to them. In case of knowledge gaps they are offered free targeted counselling as well as free HIV rapid testing and post-test counselling of HIV and hepatitis test results.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionskrankheiten / Erreger; Robert Koch-Institut, Infektionsepidemiologie
dc.subjectHIVeng
dc.subjecthepatitis Ceng
dc.subjecthepatitis Beng
dc.subjectPWIDeng
dc.subjectSero- and behavioural surveyeng
dc.subjectHTLVeng
dc.subjectRespondent driven samplingeng
dc.subjectSecond generation surveillanceeng
dc.subjectInjecting drug userseng
dc.subject.ddc610 Medizin
dc.titleA multicentre sero-behavioural survey for hepatitis B and C, HIV and HTLV among people who inject drugs in Germany using respondent driven sampling
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10037390
dc.identifier.doi10.1186/1471-2458-14-845
dc.identifier.doihttp://dx.doi.org/10.25646/1870
local.edoc.container-titleBMC Public Health
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.biomedcentral.com/1471-2458/14/845
local.edoc.container-publisher-nameBioMedCentral
local.edoc.container-volume14
local.edoc.container-issue845
local.edoc.container-year2014

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