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2015-01-23Zeitschriftenartikel DOI: 10.1186/s12879-015-0754-x
Soluble MICB protein levels and platelet counts during hepatitis B virus infection and response to hepatocellular carcinoma treatment
dc.contributor.authorTong, Hoang Van
dc.contributor.authorSong, Le Huu
dc.contributor.authorHoan, Nghiem Xuan
dc.contributor.authorCuong, Bui Khac
dc.contributor.authorSy, Bui Tien
dc.contributor.authorSon, Ho Anh
dc.contributor.authorQuyet, Do
dc.contributor.authorBinh, Vu Quoc
dc.contributor.authorKremsner, Peter G.
dc.contributor.authorBock, Thomas
dc.contributor.authorVelavan, Thirumalaisamy P.
dc.contributor.authorToan, Nguyen Linh
dc.date.accessioned2018-05-07T18:05:56Z
dc.date.available2018-05-07T18:05:56Z
dc.date.created2015-02-05
dc.date.issued2015-01-23none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reKAeZI3rka72/PDF/28FDmT6aVZwY.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2015
dc.description.abstractBackground: The human major histocompatibility complex class I polypeptide-related sequence B (MICB) is a protein that modulates the NK and T cell activation through the NKG2D receptor and is related to several diseases including cancer. Methods: The study investigated the prognostic role of soluble MICB (sMICB) protein in the progression of HBV-related liver diseases and to HBV-related HCC treatment. The sMICB serum levels were measured in 266 chronic HBV-infected Vietnamese patients and in healthy controls, and correlated with clinical and laboratory parameters and with therapeutic interventions for HBV-related HCC. Results: Significant differences in both clinical and laboratory parameters were observed among the patient groups with different stages of hepatitis. The platelet counts were significantly decreased with disease progression (P eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionskrankheiten / Erreger
dc.subjectHepatitis Beng
dc.subjectSoluble MICB proteineng
dc.subjectHepatocellular carcinomaeng
dc.subjectCancer treatmenteng
dc.subjectPlatelet countseng
dc.subject.ddc610 Medizin
dc.titleSoluble MICB protein levels and platelet counts during hepatitis B virus infection and response to hepatocellular carcinoma treatment
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10038708
dc.identifier.doi10.1186/s12879-015-0754-x
dc.identifier.doihttp://dx.doi.org/10.25646/1940
local.edoc.container-titleBMC Infectious Diseases
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.biomedcentral.com/1471-2334/15/25
local.edoc.container-publisher-nameBioMedCentral
local.edoc.container-volume15
local.edoc.container-issue25
local.edoc.container-year2015

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