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2015-04-09Zeitschriftenartikel DOI: 10.1016/j.stemcr.2015.03.002
Human Embryonic and Induced Pluripotent Stem Cell Research Trends: Complementation and Diversification of the Field
dc.contributor.authorKobold, Sabine
dc.contributor.authorGuhr, Anke
dc.contributor.authorKurtz, Andreas
dc.contributor.authorLöser, Peter
dc.date.accessioned2018-05-07T18:12:39Z
dc.date.available2018-05-07T18:12:39Z
dc.date.created2015-04-20
dc.date.issued2015-04-09none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reBwn6qIyb9Gw/PDF/24kQyQMiz9ZLA.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2051
dc.description.abstractResearch in human induced pluripotent stem cells (hiPSCs) is rapidly developing and there are expectations that this research may obviate the need to use human embryonic stem cells (hESCs), the ethics of which has been a subject of controversy for more than 15 years. In this study, we investigated approximately 3,400 original research papers that reported an experimental use of these types of human pluripotent stem cells (hPSCs) and were published from 2008 to 2013. We found that research into both cell types was conducted independently and further expanded, accompanied by a growing intersection of both research fields. Moreover, an in-depth analysis of papers that reported the use of both cell types indicates that hESCs are still being used as a “gold standard,” but in a declining proportion of publications. Instead, the expanding research field is diversifying and hESC and hiPSC lines are increasingly being used in more independent research and application areas.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Stammzellen
dc.subjectHumanseng
dc.subjectDatabases Factualeng
dc.subjectEmbryonic Stem Cells/cytologyeng
dc.subjectEmbryonic Stem Cells/metabolismeng
dc.subjectInduced Pluripotent Stem Cells/cytologyeng
dc.subjectInduced Pluripotent Stem Cells/metabolismeng
dc.subjectPublishing/statistics & numerical dataeng
dc.subjectPublishing/trendseng
dc.subjectStem Cell Research/ethicseng
dc.subject.ddc610 Medizin
dc.titleHuman Embryonic and Induced Pluripotent Stem Cell Research Trends: Complementation and Diversification of the Field
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10039329
dc.identifier.doi10.1016/j.stemcr.2015.03.002
dc.identifier.doihttp://dx.doi.org/10.25646/1976
local.edoc.container-titleStem Cell Reports
local.edoc.container-textKobold, S., Guhr, A., Kurtz, A., Löser, P. Human Embryonic and Induced Pluripotent Stem Cell Research Trends: Complementation and Diversification of the Field (2014) Stem Cell Reports
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://www.sciencedirect.com/science/article/pii/S221367111500096X
local.edoc.container-publisher-nameElsevier
local.edoc.container-volume4
local.edoc.container-issue5
local.edoc.container-year2015

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