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2016-03-08Zeitschriftenartikel DOI: 10.1371/journal.pone.0150812
Highly Predictive Model for a Protective Immune Response to the A(H1N1)pdm2009 Influenza Strain after Seasonal Vaccination
dc.contributor.authorJürchott, Karsten
dc.contributor.authorSchulz, Axel Ronald
dc.contributor.authorBozzetti, Cecilia
dc.contributor.authorPohlmann, Dominika
dc.contributor.authorStervbo, Ulrik
dc.contributor.authorWarth, Sarah
dc.contributor.authorMälzer, Julia Nora
dc.contributor.authorWaldner, Julian
dc.contributor.authorSchweiger, Brunhilde
dc.contributor.authorOlek, Sven
dc.contributor.authorGrützkau, Andreas
dc.contributor.authorBabel, Nina
dc.contributor.authorThiel, Andreas
dc.contributor.authorNeumann, Avidan Uriel
dc.date.accessioned2018-05-07T19:00:40Z
dc.date.available2018-05-07T19:00:40Z
dc.date.created2016-04-29
dc.date.issued2016-03-08none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reUHZlHaOSNOg/PDF/28ZGfH0MMEkw.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2311
dc.description.abstractUnderstanding the immune response after vaccination against new influenza strains is highly important in case of an imminent influenza pandemic and for optimization of seasonal vaccination strategies in high risk population groups, especially the elderly. Models predicting the best sero-conversion response among the three strains in the seasonal vaccine were recently suggested. However, these models use a large number of variables and/or information post- vaccination. Here in an exploratory pilot study, we analyzed the baseline immune status in young (eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionskrankheiten / Erreger
dc.subjectVaccinationeng
dc.subjectGermanyeng
dc.subjectHumanseng
dc.subjectAdulteng
dc.subjectAgedeng
dc.subjectMiddle Agedeng
dc.subjectYoung Adulteng
dc.subjectSeasonseng
dc.subjectInfluenza Human/prevention & controleng
dc.subjectAge Factorseng
dc.subjectInfluenza Human/immunologyeng
dc.subjectLymphocyte Activationeng
dc.subjectComputer Simulationeng
dc.subjectInfluenza A Virus H1N1 Subtype/immunologyeng
dc.subjectInfluenza Vaccines/immunologyeng
dc.subjectModels Statisticaleng
dc.subjectPilot Projectseng
dc.subjectT-Lymphocyte Subsets/immunologyeng
dc.subjectImmunity Innateeng
dc.subjectLymphocyte Counteng
dc.subjectT-Lymphocyte Subsets/metabolismeng
dc.subject.ddc610 Medizin
dc.titleHighly Predictive Model for a Protective Immune Response to the A(H1N1)pdm2009 Influenza Strain after Seasonal Vaccination
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10044936
dc.identifier.doi10.1371/journal.pone.0150812
dc.identifier.doihttp://dx.doi.org/10.25646/2236
local.edoc.container-titlePLoS ONE
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://journals.plos.org/plosone/article/authors?id=10.1371%2Fjournal.pone.0150812
local.edoc.container-publisher-namePublic Library of Science
local.edoc.container-volume11
local.edoc.container-issue3
local.edoc.container-year2016

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