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2016-09-01Zeitschriftenartikel DOI: 10.1186/s41124-016-0016-6
Concordance between self-reported and measured HIV and hepatitis C virus infection status among people who inject drugs in Germany
dc.contributor.authorNielsen, Stine
dc.contributor.authorGassowski, Martyna
dc.contributor.authorWenz, Benjamin
dc.contributor.authorBannert, Norbert
dc.contributor.authorBock, Thomas
dc.contributor.authorKücherer, Claudia
dc.contributor.authorRoss, Stefan
dc.contributor.authorBremer, Viviane
dc.contributor.authorMarcus, Ulrich
dc.contributor.authorZimmermann, Ruth
dc.date.accessioned2018-05-07T19:18:20Z
dc.date.available2018-05-07T19:18:20Z
dc.date.created2016-09-01
dc.date.issued2016-09-01none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/reaoVrlkvDis/PDF/2218oqSqG4ARE.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2408
dc.description.abstractBackground: People who inject drugs (PWID) are disproportionately affected by both HIV and hepatitis C infection (HCV). Awareness of infection status is essential to ensure linkage to appropriate healthcare for those infected, who need treatment and regular follow-up, as well as for uninfected individuals, who need access to targeted testing and counselling services. In this paper we compare self-reported HIV and HCV status with serological markers of infection among PWID recruited through respondent driven sampling. Methods: From 2011 through 2014, biological and behavioural data was collected from 2,077 PWID in Germany. Dried blood spots from capillary blood samples were collected and screened for HCV antibodies, HCV RNA and HIV-1/-2 antibodies. HIV reactive samples were confirmed by Western blot. Results: Laboratory testing revealed that 5 % were infected with HIV and 81 % were aware of being infected. Chronic HCV infection was detected in 41 % of the participants, 2 % had an acute HCV infection, 22 % had a cleared infection, and 34 % were unexposed to HCV. The concordance between self-reported and measured HCV status was lower than for HIV, with 73 % of those with chronic HCV infection being aware of their infection. Conclusions: We found a relatively high awareness of HIV and HCV infection status among PWID. Nevertheless, access to appropriate testing, counselling and care services targeted to the needs of PWID should be further improved, particularly concerning HCV. Trial registration: Ethical approval was received from the ethics committee at the medical university of Charité, Berlin, Germany in May 2011 and with an amendment approved retrospectively on 19/11/2012 (No EA4/036/11). The German Federal Commissioner for Data Protection and Freedom of Information approved the study protocol retrospectively on 29/11/2012 (III-401/008#0035).eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Epidemiologie und Gesundheitsberichterstattung
dc.subjectGermanyeng
dc.subjectHIVeng
dc.subjectHepatitis Ceng
dc.subjectRespondent driven samplingeng
dc.subjectTestingeng
dc.subjectPeople who inject drugseng
dc.subjectKnowledgeeng
dc.subjectSelf-reporteng
dc.subjectValidityeng
dc.subjectUndiagnosedeng
dc.subject.ddc610 Medizin
dc.titleConcordance between self-reported and measured HIV and hepatitis C virus infection status among people who inject drugs in Germany
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10046684
dc.identifier.doi10.1186/s41124-016-0016-6
dc.identifier.doihttp://dx.doi.org/10.25646/2333
local.edoc.container-titleHepatology, Medicine and Policy
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttps://hmap.biomedcentral.com/articles/10.1186/s41124-016-0016-6
local.edoc.container-publisher-nameBioMedCentral
local.edoc.container-volume1
local.edoc.container-issue8
local.edoc.container-year2016

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