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2016-08-28Zeitschriftenartikel DOI: 10.1099/mgen.0.000070
Phylogenetic structure of European Salmonella Enteritidis outbreak correlates with national and international egg distribution network
dc.contributor.authorDallman, Tim
dc.contributor.authorInns, Thomas
dc.contributor.authorJombart, Thibaut
dc.contributor.authorAshton, Philip
dc.contributor.authorLoman, Nicolas
dc.contributor.authorChatt, Carol
dc.contributor.authorMesselhaeusser, Ute
dc.contributor.authorRabsch, Wolfgang
dc.contributor.authorSimon, Sandra
dc.contributor.authorNikisins, Sergejs
dc.contributor.authorBernard, Helen
dc.contributor.authorHello, Simon le
dc.contributor.authorda-Silva, Nathalie Jourdan
dc.contributor.authorKornschober, Christian
dc.contributor.authorMossong, Joel
dc.contributor.authorHawkey, Peter
dc.contributor.authorPinna, Elizabeth de
dc.contributor.authorGrant, Kathie
dc.contributor.authorCleary, Paul
dc.date.accessioned2018-05-07T19:55:38Z
dc.date.available2018-05-07T19:55:38Z
dc.date.created2017-04-07
dc.date.issued2016-08-28none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/revrIfiOGFT7o/PDF/241NQI5w0CAQ.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2609
dc.description.abstractOutbreaks of Salmonella Enteritidis have long been associated with contaminated poultry and eggs. In the summer of 2014 a large multi-national outbreak of Salmonella Enteritidis phage type 14b occurred with over 350 cases reported in the United Kingdom, Germany, Austria, France and Luxembourg. Egg supply network investigation and microbiological sampling identified the source to be a Bavarian egg producer. As part of the international investigation into the outbreak, over 400 isolates were sequenced including isolates from cases, implicated UK premises and eggs from the suspected source producer. We were able to show a clear statistical correlation between the topology of the UK egg distribution network and the phylogenetic network of outbreak isolates. This correlation can most plausibly be explained by different parts of the egg distribution network being supplied by eggs solely from independent premises of the Bavarian egg producer (Company X). Microbiological sampling from the source premises, traceback information and information on the interventions carried out at the egg production premises all supported this conclusion. The level of insight into the outbreak epidemiology provided by whole-genome sequencing (WGS) would not have been possible using traditional microbial typing methods.eng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionskrankheiten / Erreger
dc.subjectSalmonellaeng
dc.subjectwhole-genome sequencingeng
dc.subjecttraceback investigationeng
dc.subjectfoodborne outbreakeng
dc.subject.ddc610 Medizin
dc.titlePhylogenetic structure of European Salmonella Enteritidis outbreak correlates with national and international egg distribution network
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10052080
dc.identifier.doi10.1099/mgen.0.000070
dc.identifier.doihttp://dx.doi.org/10.25646/2534
local.edoc.container-titleMicrobial Genomics
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://mgen.microbiologyresearch.org/content/journal/mgen/10.1099/mgen.0.000070
local.edoc.container-publisher-nameSociety for General Microbiology
local.edoc.container-volume2
local.edoc.container-issue8
local.edoc.container-year2016

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