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2017-11-22Zeitschriftenartikel DOI: 10.1371/journal.pone.0188356
Integration of molecular typing results into tuberculosis surveillance in Germany—A pilot study
dc.contributor.authorAndrés, Marta
dc.contributor.authorGöhring-Zwacka, Elke
dc.contributor.authorFiebig, Lena
dc.contributor.authorPriwitzer, Martin
dc.contributor.authorRichter, Elvira
dc.contributor.authorRüsch-Gerdes, Sabine
dc.contributor.authorHaas, Walter
dc.contributor.authorNiemann, Stefan
dc.contributor.authorBrodhun, Bonita
dc.date.accessioned2018-05-07T21:00:50Z
dc.date.available2018-05-07T21:00:50Z
dc.date.created2018-01-30
dc.date.issued2017-11-22none
dc.identifier.otherhttp://edoc.rki.de/oa/articles/rezLwQndLqcOw/PDF/25VihgzROmTH2.pdf
dc.identifier.urihttp://edoc.rki.de/176904/2960
dc.description.abstractAn integrated molecular surveillance for tuberculosis (TB) improves the understanding of ongoing TB transmission by combining molecular typing and epidemiological data. However, the implementation of an integrated molecular surveillance for TB is complex and requires thoughtful consideration of feasibility, demand, public health benefits and legal issues. We aimed to pilot the integration of molecular typing results between 2008 and 2010 in the German Federal State of Baden-Württemberg (population 10.88 Million) as preparation for a nationwide implementation. Culture positive TB cases were typed by IS6110 DNA fingerprinting and results were integrated into routine notification data. Demographic and clinical characteristics of cases and clusters were described and new epidemiological links detected after integrating typing data were calculated. Furthermore, a cross-sectional survey was performed among local public health offices to evaluate their perception and experiences. Overall, typing results were available for 83% of notified culture positive TB cases, out of which 25% were clustered. Ageeng
dc.language.isoeng
dc.publisherRobert Koch-Institut, Infektionsepidemiologie
dc.subject.ddc610 Medizin
dc.titleIntegration of molecular typing results into tuberculosis surveillance in Germany—A pilot study
dc.typeperiodicalPart
dc.identifier.urnurn:nbn:de:0257-10057173
dc.identifier.doi10.1371/journal.pone.0188356
dc.identifier.doihttp://dx.doi.org/10.25646/2885
local.edoc.container-titlePLoS ONE
local.edoc.fp-subtypeArtikel
local.edoc.type-nameZeitschriftenartikel
local.edoc.container-typeperiodical
local.edoc.container-type-nameZeitschrift
local.edoc.container-urlhttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188356
local.edoc.container-publisher-namePublic Library of Science
local.edoc.container-volume12
local.edoc.container-issue11
local.edoc.container-year2017

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