2024-02-05Zeitschriftenartikel
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome
Krischuns, Tim; Arragain, Benoît; Isel, Catherine; Paisant, Sylvain; Budt, Matthias; Wolff, Thorsten; Cusack, Stephen; Naffakh, Nadia
The current model is that the influenza virus polymerase (FluPol) binds either to host RNA polymerase II (RNAP II) or to the acidic nuclear phosphoprotein 32 (ANP32), which drives its conformation and activity towards ...