Background: The HIV-1 p6 Gag protein regulates the final abscission step of nascent virions from the cell membrane by the action of two late assembly (L-) domains. Although p6 is located within one of the most polymorphic ...

Die Alterung der Gesellschaft, so wird angenommen, wird zu einem Anstieg der Zahl an erkrankten Menschen beziehungsweise der Neuerkrankungen und zu steigenden Belastungen des Gesundheitssystems führen. Morbiditätsprognosen ...

We assessed the prediction that access of the viral NS1 protein to cellular PDZ domain protein networks enhances the virulence of highly pathogenic avian influenza A viruses. The NS1 proteins of most avian influenza viruses ...

Botulinum neurotoxin (BoNT) is the most toxic substance known to man and the causative agent of botulism. Due to its high toxicity and the availability of the producing organism Clostridium botulinum, BoNT is regarded as ...

Hintergrund: Die Masernelimination in Europa bis 2015 ist ein WHO-Gesundheitsziel. In Deutschland besteht gemäß Infektionsschutzgesetz (IfSG) eine Meldepflicht für Masernerkrankungen, dennoch geht man von einer Untererfassung ...

Objective: To evaluate the impact of a family-oriented inpatient rehabilitation programme on behavioural and emotional problems in healthy siblings of chronically ill children and to assess the association between these ...

Ganciclovir (GCV) resistance frequently occurs upon prolonged treatment of ongoing active human cytomegalovirus (HCMV) infection in individuals with immature or compromised immune functions (e.g., recipients of solid-organ ...

The Robert Koch Institute is currently conducting the "German Health Interview and Examination Survey for Adults (DEGS)". Its aim is to provide comprehensive data on the health situation of Germany‘s resident population. ...

Background: Many efforts have been made to understand basal mechanisms of mycobacterial infections. Macrophages are the first line of host immune defence to encounter and eradicate mycobacteria. Pathogenic species have ...