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2012-12-26Zeitschriftenartikel

Biological and Phylogenetic Characteristics of Yellow Fever Virus Lineages from West Africa

Stock, Nina K.; Laraway, Hewád; Faye, Ousmane; Diallo, Mawlouth; Niedrig, Matthias; Sall, Amadou A.

The yellow fever virus (YFV), the first proven human-pathogenic virus, although isolated in 1927, is still a major public health problem, especially in West Africa where it causes outbreaks every year. Nevertheless, little ...

2013-10-08Zeitschriftenartikel

The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue

Knepper, Jessica; Schierhorn, Kristina L.; Becher, Anne; Budt, Matthias; Tönnies, Mario; Bauer, Torsten T.; Schneider, Paul; Neudecker, Jens; Rückert, Jens C.; Gruber, Achim D.; Suttorp, Norbert; Schweiger, Brunhilde; Hippenstiel, Stefan; Hocke, Andreas C.; Wolff, Thorsten

A novel influenza A virus (IAV) of the H7N9 subtype has been isolated from severely diseased patients with pneumonia and acute respiratory distress syndrome and, apparently, from healthy poultry in March 2013 in Eastern ...

2013-10-23Zeitschriftenartikel

Koala retroviruses: characterization and impact on the life of koalas

Denner, Joachim; Young, Paul R.

Koala retroviruses (KoRV) have been isolated from wild and captive koalas in Australia as well as from koala populations held in zoos in other countries. They are members of the genus Gammaretrovirus, are most closely ...

2013-10-16Zeitschriftenartikel

Hygiene perception changes during the influenza A H1N1 pandemic in Germany: incorporating the results of two cross-sectional telephone surveys 2008–2009

Meilicke, Gerald; Riedmann, Klaus; Biederbick, Walter; Müller, Ute; Wierer, Traugott; Bartels, Cornelius

Background: The federal campaign Wir gegen Viren [Us against viruses] promoted hygiene in Germany during the influenza A H1N1 pandemic in 2009. The intervention aimed to encourage people to protect themselves against ...

2013-10-24Zeitschriftenartikel

Development of a risk assessment tool for contact tracing people after contact with infectious patients while travelling by bus or other public ground transport: a Delphi consensus approach

Mohr, Oliver; Hermes, Julia; Schink, Susanne; Askar, Mona; Menucci, Daniel; Swaan, Corien; Goetsch, Udo; Monk, Philip; Eckmanns, Tim; Poggensee, Gabriele; Krause, Gérard

Background: Tracing persons who have been in contact with an infectious patient may be very effective in preventing the spread of communicable diseases. However, criteria to decide when to conduct contact tracing are not ...

2013-11-04Zeitschriftenartikel

Increased expression of CD25, CD83, and CD86, and secretion of IL-12, IL-23, and IL-10 by human dendritic cells incubated in the presence of Toll-like receptor 2 ligands and Giardia duodenalis

Obendorf, Janine; Viveros, Pablo Renner; Fehlings, Michael; Klotz, Christian; Aebischer, Toni; Ignatius, Ralf

Background: Effects of Giardia duodenalis on dendritic cell (DC) functions may contribute to the pathogenesis of chronic giardiasis. G. duodenalis lysate has been shown to inhibit the activation of murine DCs through ...

2013-11-01Zeitschriftenartikel

Middle East Respiratory Syndrome Coronavirus (MERS-CoV): An die Reiseanamnese denken

Buchholz, Udo; Buda, Silke; Haas, Walter

Das Robert-Koch-Institut gibt Hinweise zur Identifizierung von Patienten mit Verdacht auf MERS-CoV-Infektion und zu den erforderlichen Infektionsschutzmaßnahmen für medizinisches Personal. Besondere Beachtung gilt Touristen ...

2012-12-30Zeitschriftenartikel

Complete Genome Sequence of the English Isolate of Rat Cytomegalovirus (Murid Herpesvirus 8)

Ettinger, Jakob; Geyer, Henriette; Nitsche, Andreas; Zimmermann, Albert; Brune, Wolfram; Sandford, Gordon R.; Hayward, Gary S.; Voigt, Sebastian

The complete genome of the English isolate of rat cytomegalovirus (RCMV-E) was determined. RCMV-E has a 202,946-bp genome with noninverting repeats but without terminal repeats. Thus, it differs significantly in size and ...

2012-10-03Zeitschriftenartikel

Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients

Theys, Kristof; Deforche, Koen; Vercauteren, Jurgen; Libin, Pieter; Vijver, David A. M. C. van de; Albert, Jan; Åsjö, Birgitta; Balotta, Claudia; Bruckova, Marie; Camacho, Ricardo J.; Clotet, Bonaventura; Coughlan, Suzie; Grossman, Zehava; Hamouda, Osamah; Horban, Andrzei; Korn, Klaus; Kostrikis, Leondios G.; Kücherer, Claudia; Nielsen, Claus; Paraskevis, Dimitrios; Poljak, Mario; Puchhammer-Stockl, Elisabeth; Riva, Chiara; Ruiz, Lidia; Liitsola, Kirsi

Background: The effect of drug resistance transmission on disease progression in the newly infected patient is not well understood. Major drug resistance mutations severely impair viral fitness in a drug free environment, ...

2012-12-14Zeitschriftenartikel

Messung des sozioökonomischen Status in der Studie „Gesundheit in Deutschland aktuell“ (GEDA)

Lampert, Thomas; Kroll, Lars Eric; Müters, Stephan; Stolzenberg, Heribert

Der sozioökonomische Status (SES) stellt eine zentrale Analysekategorie der epidemiologischen Forschung und Gesundheitsberichterstattung dar. Im Rahmen der Deutschen Herz-Kreislauf-Präventionsstudie wurde zur Messung des ...

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